Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations AV Khera, M Chaffin, KG Aragam, ME Haas, C Roselli, SH Choi, ... Nature genetics 50 (9), 1219-1224, 2018 | 2638 | 2018 |
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis AV Khera, M Cuchel, M de la Llera-Moya, A Rodrigues, MF Burke, K Jafri, ... New England Journal of Medicine 364 (2), 127-135, 2011 | 2293 | 2011 |
Mendelian randomization CA Emdin, AV Khera, S Kathiresan Jama 318 (19), 1925-1926, 2017 | 1899 | 2017 |
Genetic risk, adherence to a healthy lifestyle, and coronary disease AV Khera, CA Emdin, I Drake, P Natarajan, AG Bick, NR Cook, ... New England Journal of Medicine 375 (24), 2349-2358, 2016 | 1380 | 2016 |
Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia AV Khera, HH Won, GM Peloso, KS Lawson, TM Bartz, X Deng, ... Journal of the American College of Cardiology 67 (22), 2578-2589, 2016 | 941 | 2016 |
A structural variation reference for medical and population genetics RL Collins, H Brand, KJ Karczewski, X Zhao, J Alföldi, LC Francioli, ... Nature 581 (7809), 444-451, 2020 | 765 | 2020 |
Polygenic prediction of weight and obesity trajectories from birth to adulthood AV Khera, M Chaffin, KH Wade, S Zahid, J Brancale, R Xia, M Distefano, ... Cell 177 (3), 587-596. e9, 2019 | 671 | 2019 |
Genetics of coronary artery disease: discovery, biology and clinical translation AV Khera, S Kathiresan Nature Reviews Genetics 18 (6), 331-344, 2017 | 661 | 2017 |
Genetics of blood lipids among~ 300,000 multi-ethnic participants of the Million Veteran Program D Klarin, SM Damrauer, K Cho, YV Sun, TM Teslovich, J Honerlaw, ... Nature genetics 50 (11), 1514-1523, 2018 | 578 | 2018 |
Monkeys pay per view: adaptive valuation of social images by rhesus macaques RO Deaner, AV Khera, ML Platt Current Biology 15 (6), 543-548, 2005 | 563 | 2005 |
Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 554 | 2017 |
Lipoprotein (a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an … AV Khera, BM Everett, MP Caulfield, FM Hantash, J Wohlgemuth, ... Circulation 129 (6), 635-642, 2014 | 483 | 2014 |
ANGPTL3 deficiency and protection against coronary artery disease NO Stitziel, AV Khera, X Wang, AJ Bierhals, AC Vourakis, AE Sperry, ... Journal of the American College of Cardiology 69 (16), 2054-2063, 2017 | 452 | 2017 |
A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression RM Gupta, J Hadaya, A Trehan, SM Zekavat, C Roselli, D Klarin, ... Cell 170 (3), 522-533. e15, 2017 | 421 | 2017 |
Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes, and coronary heart disease CA Emdin, AV Khera, P Natarajan, D Klarin, SM Zekavat, AJ Hsiao, ... Jama 317 (6), 626-634, 2017 | 410 | 2017 |
A single-cell atlas of human and mouse white adipose tissue MP Emont, C Jacobs, AL Essene, D Pant, D Tenen, G Colleluori, ... Nature 603 (7903), 926-933, 2022 | 390 | 2022 |
Improving reporting standards for polygenic scores in risk prediction studies H Wand, SA Lambert, C Tamburro, MA Iacocca, JW O’Sullivan, C Sillari, ... Nature 591 (7849), 211-219, 2021 | 353 | 2021 |
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ... Nature communications 11 (1), 1-9, 2020 | 350 | 2020 |
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants KG Aragam, T Jiang, A Goel, S Kanoni, BN Wolford, DS Atri, EM Weeks, ... Nature Genetics 54 (12), 1803-1815, 2022 | 284 | 2022 |
Lp (a)(lipoprotein [a]) concentrations and incident atherosclerotic cardiovascular disease: new insights from a large national biobank AP Patel, M Wang, JP Pirruccello, PT Ellinor, K Ng, S Kathiresan, ... Arteriosclerosis, Thrombosis, and Vascular Biology 41 (1), 465-474, 2021 | 277 | 2021 |