| Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR R van Eijk, J Licht, M Schrumpf, M Talebian Yazdi, D Ruano, GI Forte, ... PloS one 6 (3), e17791, 2011 | 214 | 2011 |
| Genomic characterization of vulvar (pre) cancers identifies distinct molecular subtypes with prognostic significance LS Nooij, NT Ter Haar, D Ruano, N Rakislova, T van Wezel, VT Smit, ... Clinical Cancer Research 23 (22), 6781-6789, 2017 | 135 | 2017 |
| Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer FA Elsayed, CM Kets, D Ruano, B Van Den Akker, AR Mensenkamp, ... European Journal of Human Genetics 23 (8), 1080-1084, 2015 | 134 | 2015 |
| Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability D Ruano, GR Abecasis, B Glaser, ES Lips, LN Cornelisse, APH de Jong, ... The American Journal of Human Genetics 86 (2), 113-125, 2010 | 134 | 2010 |
| Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers AML Jansen, T Van Wezel, BE Van Den Akker, M Ventayol Garcia, ... European Journal of Human Genetics 24 (7), 1089-1092, 2016 | 132 | 2016 |
| γδ T cells are effectors of immunotherapy in cancers with HLA class I defects NL de Vries, J van de Haar, V Veninga, M Chalabi, ME Ijsselsteijn, ... Nature 613 (7945), 743-750, 2023 | 127 | 2023 |
| Whole-Exome Sequencing Studies of Parathyroid Carcinomas Reveal Novel PRUNE2 Mutations, Distinctive Mutational Spectra Related to APOBEC-Catalyzed … W Yu, JR McPherson, M Stevenson, R van Eijk, HL Heng, P Newey, ... The Journal of Clinical Endocrinology & Metabolism 100 (2), E360-E364, 2015 | 111 | 2015 |
| Revisiting thyroid hormones in schizophrenia NC Santos, P Costa, D Ruano, A Macedo, MJ Soares, J Valente, ... Journal of thyroid research 2012 (1), 569147, 2012 | 103 | 2012 |
| Molecular analysis of gene fusions in bone and soft tissue tumors by anchored multiplex PCR–based targeted next-generation sequencing SW Lam, AM Cleton-Jansen, AHG Cleven, D Ruano, T van Wezel, ... The Journal of Molecular Diagnostics 20 (5), 653-663, 2018 | 101 | 2018 |
| Optimizing mutation and fusion detection in NSCLC by sequential DNA and RNA sequencing D Cohen, LM Hondelink, N Solleveld-Westerink, SM Uljee, D Ruano, ... Journal of Thoracic Oncology 15 (6), 1000-1014, 2020 | 91 | 2020 |
| Genome haploidisation with chromosome 7 retention in oncocytic follicular thyroid carcinoma WE Corver, D Ruano, K Weijers, WCE Den Hartog, ... PloS one 7 (6), e38287, 2012 | 82 | 2012 |
| Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer A Fariña Sarasqueta, GI Forte, WE Corver, NF de Miranda, D Ruano, ... BMC cancer 13, 1-11, 2013 | 67 | 2013 |
| Association of the gene encoding neurogranin with schizophrenia in males D Ruano, YS Aulchenko, A Macedo, MJ Soares, J Valente, MH Azevedo, ... Journal of psychiatric research 42 (2), 125-133, 2008 | 66 | 2008 |
| Identification of a neo-epitope dominating endogenous CD8 T cell responses to MC-38 colorectal cancer BJ Hos, MGM Camps, J Bulk, E Tondini, TC Ende, D Ruano, K Franken, ... Oncoimmunology 9 (1), 1673125, 2020 | 65 | 2020 |
| Prevalence and prognosis of lynch syndrome and sporadic mismatch repair deficiency in endometrial cancer CCB Post, E Stelloo, VT Smit, D Ruano, CM Tops, L Vermij, TA Rutten, ... JNCI: Journal of the National Cancer Institute 113 (9), 1212-1220, 2021 | 63 | 2021 |
| Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4 J Van Den Bulk, EME Verdegaal, D Ruano, ME Ijsselsteijn, M Visser, ... Genome medicine 11, 1-15, 2019 | 59 | 2019 |
| Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell cycle progression in a preclinical model S Kumar, MJA Schoonderwoerd, JS Kroonen, IJ de Graaf, M Sluijter, ... Gut 71 (11), 2266-2283, 2022 | 55 | 2022 |
| Molecular background of colorectal tumors from patients with Lynch syndrome associated with germline variants in PMS2 SW Ten Broeke, TC van Bavel, AML Jansen, E Gómez-García, FJ Hes, ... Gastroenterology 155 (3), 844-851, 2018 | 54 | 2018 |
| Distinct patterns of somatic mosaicism in the APC gene in neoplasms from patients with unexplained adenomatous polyposis AML Jansen, S Crobach, WRR Geurts-Giele, BEWM van den Akker, ... Gastroenterology 152 (3), 546-549. e3, 2017 | 42 | 2017 |
| Revisiting immune escape in colorectal cancer in the era of immunotherapy ME Ijsselsteijn, F Petitprez, L Lacroix, D Ruano, R van Der Breggen, ... British journal of cancer 120 (8), 815-818, 2019 | 41 | 2019 |
Tom van WezelAssociate professor, Department of Pathology, Leiden University Medical Center, NetherlandsVerified email at lumc.nl