Structure- and function-based design of Plasmodium-selective proteasome inhibitors H Li, AJ O’Donoghue, WA Van Der Linden, SC Xie, E Yoo, IT Foe, L Tilley, ... Nature 530 (7589), 233-236, 2016 | 256 | 2016 |
Directed Evolution of Ionizing Radiation Resistance in Escherichia coli DR Harris, SV Pollock, EA Wood, RJ Goiffon, AJ Klingele, EL Cabot, ... Journal of bacteriology 191 (16), 5240-5252, 2009 | 161 | 2009 |
Skin commensal Malassezia globosa secreted protease attenuates Staphylococcus aureus biofilm formation H Li, BN Goh, WK Teh, Z Jiang, JPZ Goh, A Goh, G Wu, SS Hoon, ... Journal of Investigative Dermatology 138 (5), 1137-1145, 2018 | 130 | 2018 |
Non-invasive imaging of idiopathic pulmonary fibrosis using cathepsin protease probes NP Withana, X Ma, HM McGuire, M Verdoes, WA van der Linden, LO Ofori, ... Scientific reports 6 (1), 19755, 2016 | 103 | 2016 |
A wireless and battery-free wound infection sensor based on DNA hydrogel Z Xiong, S Achavananthadith, S Lian, LE Madden, ZX Ong, W Chua, ... Science advances 7 (47), eabj1617, 2021 | 94 | 2021 |
Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity H Li, EL Ponder, M Verdoes, KH Asbjornsdottir, E Deu, LE Edgington, ... Chemistry & biology 19 (12), 1535-1545, 2012 | 94 | 2012 |
Proteases as regulators of pathogenesis: examples from the Apicomplexa H Li, MA Child, M Bogyo Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (1), 177-185, 2012 | 80 | 2012 |
Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization K Oresic Bender, L Ofori, WA van der Linden, ED Mock, GK Datta, ... Journal of the American Chemical Society 137 (14), 4771-4777, 2015 | 75 | 2015 |
Identification of Potent and Selective Non-covalent Inhibitors of the Plasmodium falciparum Proteasome H Li, C Tsu, C Blackburn, G Li, P Hales, L Dick, M Bogyo Journal of the American Chemical Society 136 (39), 13562-13565, 2014 | 56 | 2014 |
Assessing Subunit Dependency of the Plasmodium Proteasome Using Small Molecule Inhibitors and Active Site Probes H Li, WA Van Der Linden, M Verdoes, BI Florea, FE McAllister, ... ACS chemical biology 9 (8), 1869-1876, 2014 | 55 | 2014 |
The cryo‐EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria H Li, M Bogyo, PCA da Fonseca The FEBS journal 283 (23), 4238-4243, 2016 | 36 | 2016 |
Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation SE Poh, JPZ Goh, C Fan, W Chua, SQ Gan, PLK Lim, B Sharma, ... Frontiers in cellular and infection microbiology 10, 148, 2020 | 31 | 2020 |
Templated chemistry for sequence‐specific fluorogenic detection of duplex DNA H Li, RM Franzini, C Bruner, ET Kool ChemBioChem 11 (15), 2132-2137, 2010 | 28 | 2010 |
Defective dissociation of a “slow” RecA mutant protein imparts an Escherichia coli growth defect JM Cox, H Li, EA Wood, S Chitteni-Pattu, RB Inman, MM Cox Journal of Biological Chemistry 283 (36), 24909-24921, 2008 | 26 | 2008 |
Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo E Deu, IT Chen, EMW Lauterwasser, J Valderramos, H Li, LE Edgington, ... Proceedings of the National Academy of Sciences 110 (45), 18244-18249, 2013 | 25 | 2013 |
Total Synthesis and Biological Evaluation of the Fab‐Inhibitory Antibiotic Platencin and Analogues Thereof GYC Leung, H Li, QY Toh, AMY Ng, RJ Sum, JE Bandow, DYK Chen European Journal of Organic Chemistry 2011 (1), 183-196, 2011 | 24 | 2011 |
The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation JPZ Goh, F Ruchti, SE Poh, WLC Koh, KY Tan, YT Lim, STG Thng, ... Proceedings of the National Academy of Sciences 119 (49), e2212533119, 2022 | 18 | 2022 |
Trioxolane-mediated delivery of mefloquine limits brain exposure in a mouse model of malaria EMW Lauterwasser, SD Fontaine, H Li, J Gut, K Katneni, SA Charman, ... ACS Medicinal Chemistry Letters 6 (11), 1145-1149, 2015 | 17 | 2015 |
Secretory proteases of the human skin microbiome W Chua, SE Poh, H Li Infection and Immunity 90 (1), e00397-21, 2022 | 16 | 2022 |
Expression of Staphylococcus aureus virulence factors in atopic dermatitis SE Poh, WLC Koh, SYD Lim, ECE Wang, YW Yew, JEA Common, ... JID Innovations 2 (4), 100130, 2022 | 11 | 2022 |