Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion GA Kyriazis, MM Soundarapandian, B Tyrberg Proceedings of the National Academy of Sciences 109 (8), E524-E532, 2012 | 251 | 2012 |
Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness S Chigurupati, R Venkataraman, D Barrera, A Naganathan, M Madan, ... Cancer research 70 (1), 418-427, 2010 | 229 | 2010 |
Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death L Cilenti, MM Soundarapandian, GA Kyriazis, V Stratico, S Singh, S Gupta, ... Journal of Biological Chemistry 279 (48), 50295-50301, 2004 | 229 | 2004 |
Effects of plyometric exercise on muscle soreness and plasma creatine kinase levels and its comparison with eccentric and concentric exercise AZ JAMURTAS, IG FATOUROS, P Buckenmeyer, E KOKKINIDIS, ... The Journal of Strength & Conditioning Research 14 (1), 68-74, 2000 | 162 | 2000 |
Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells SL Chan, D Liu, GA Kyriazis, P Bagsiyao, X Ouyang, MP Mattson Journal of Biological Chemistry 281 (49), 37391-37403, 2006 | 124 | 2006 |
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease … GA Kyriazis, Z Wei, M Vandermey, DG Jo, O Xin, MP Mattson, SL Chan Journal of Biological Chemistry 283 (37), 25492-25502, 2008 | 99 | 2008 |
Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells L Cilenti, GA Kyriazis, MM Soundarapandian, V Stratico, A Yerkes, ... American Journal of Physiology-Renal Physiology 288 (2), F371-F379, 2005 | 98 | 2005 |
The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium … C Belal, NJ Ameli, A El Kommos, S Bezalel, AM Al'Khafaji, MR Mughal, ... Human molecular genetics 21 (5), 963-977, 2012 | 92 | 2012 |
High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice J Serrano, KR Smith, AL Crouch, V Sharma, F Yi, V Vargova, TE LaMoia, ... Microbiome 9, 1-18, 2021 | 79 | 2021 |
Sweet taste receptors regulate basal insulin secretion and contribute to compensatory insulin hypersecretion during the development of diabetes in male mice GA Kyriazis, KR Smith, B Tyrberg, T Hussain, RE Pratley Endocrinology 155 (6), 2112-2121, 2014 | 64 | 2014 |
The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a … S Chigurupati, Z Wei, C Belal, M Vandermey, GA Kyriazis, TV Arumugam, ... Journal of biological chemistry 284 (27), 18323-18333, 2009 | 61 | 2009 |
Moderate exercise-induced energy expenditure does not alter leptin levels in sedentary obese men GA Kyriazis, JD Caplan, J Lowndes, RL Carpenter, KE Dennis, SA Sivo, ... Clinical journal of sport medicine 17 (1), 49-51, 2007 | 50 | 2007 |
T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways K Smith, EK Azari, TE LaMoia, T Hussain, V Vargova, K Karolyi, ... Molecular Metabolism 17, 98-111, 2018 | 43 | 2018 |
Disruption of the sugar-sensing receptor T1R2 attenuates metabolic derangements associated with diet-induced obesity KR Smith, T Hussain, E Karimian Azari, JL Steiner, JE Ayala, RE Pratley, ... American Journal of Physiology-Endocrinology and Metabolism 310 (8), E688-E698, 2016 | 41 | 2016 |
Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel GA Kyriazis, C Belal, M Madan, DG Taylor, J Wang, Z Wei, JV Pattisapu, ... Journal of Biological Chemistry 285 (9), 6811-6825, 2010 | 32 | 2010 |
Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study EK Azari, KR Smith, F Yi, TF Osborne, R Bizzotto, A Mari, RE Pratley, ... The American journal of clinical nutrition 105 (4), 1001-1009, 2017 | 31 | 2017 |
Omi/HtrA2 and XIAP are components of platelet apoptosis signalling J Winkler, ML Rand, M Schmugge, O Speer Thrombosis and haemostasis 109 (03), 532-539, 2013 | 31 | 2013 |
Leptin responses to long-term cardiorespiratory exercise training without concomitant weight loss: a prospective study J Lowndes, RF Zoeller, JD Caplan, GA Kyriazis, NM Moyna, RL Seip, ... Journal of sports medicine and physical fitness 48 (3), 391, 2008 | 26 | 2008 |
NIH workshop report: sensory nutrition and disease DR Reed, AL Alhadeff, GK Beauchamp, N Chaudhari, VB Duffy, M Dus, ... The American journal of clinical nutrition 113 (1), 232-245, 2021 | 19 | 2021 |
The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans J Serrano, J Seflova, J Park, M Pribadi, K Sanematsu, N Shigemura, ... Molecular Metabolism 54, 101339, 2021 | 11 | 2021 |