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Chang Jie Mick Lee
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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
JS Hawe, R Wilson, KT Schmid, L Zhou, LN Lakshmanan, BC Lehne, ...
Nature genetics 54 (1), 18-29, 2022
822022
Robust CTCF-based chromatin architecture underpins epigenetic changes in the heart failure stress–gene response
DP Lee, WLW Tan, CG Anene-Nzelu, CJM Lee, PY Li, TDA Luu, CX Chan, ...
Circulation 139 (16), 1937-1956, 2019
492019
Epigenomes of human hearts reveal new genetic variants relevant for cardiac disease and phenotype
WLW Tan, CG Anene-Nzelu, E Wong, CJM Lee, HS Tan, SJ Tang, ...
Circulation research 127 (6), 761-777, 2020
432020
Genomic enhancers in cardiac development and disease
CG Anene-Nzelu, MCJ Lee, WLW Tan, A Dashi, RSY Foo
Nature Reviews Cardiology 19 (1), 7-25, 2022
252022
The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases
NWS Chew, B Chong, CH Ng, G Kong, YH Chin, W Xiao, M Lee, YY Dan, ...
Frontiers in Genetics 13, 971484, 2022
242022
Assigning distal genomic enhancers to cardiac disease–causing genes
CG Anene-Nzelu, WLW Tan, CJM Lee, Z Wenhao, A Perrin, A Dashi, ...
Circulation 142 (9), 910-912, 2020
122020
Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
MI Autio, E Motakis, A Perrin, TB Amin, Z Tiang, DV Do, J Wang, J Tan, ...
Elife 13, e79592, 2024
62024
BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation
DCP Wong, J Xiao, TW Chew, M Pan, CJM Lee, JW Ang, I Yow, ...
Advanced Science 9 (31), 2202834, 2022
62022
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
CY Tan, PS Chan, H Tan, SW Tan, CJM Lee, JW Wang, S Ye, H Werner, ...
Journal of Translational Medicine 21 (1), 690, 2023
52023
Genome-wide CRISPR screen identifies an NF2-adherens junction mechanistic dependency for cardiac lineage
CJM Lee, MI Autio, W Zheng, Y Song, SC Wang, DCP Wong, J Xiao, ...
Circulation 149 (25), 1960-1979, 2024
12024
Metabolome-wide association of carotid intima media thickness identifies FDX1 as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations
N Sadhu, R Dalan, PR Jain, CJM Lee, LS Pakkiri, KY Tay, TH Mina, ...
medRxiv, 2024.05. 14.24307316, 2024
12024
Ultra‐Tough Graphene Oxide/DNA 2D Hydrogel with Intrinsic Sensing and Actuation Functions
S Chen, CJM Lee, GSX Tan, PR Ng, P Zhang, J Zhao, KS Novoselov, ...
Macromolecular Rapid Communications, 2400518, 2024
12024
Disease and phenotype relevant genetic variants identified from histone acetylomes in human hearts
WL Wen Tan, CG Anene-Nzelu, E Wong, HS Tan, P Bangfen, CJM Lee, ...
bioRxiv, 536763, 2019
12019
Atrial fibrillation variant-to-gene prioritization through cross-ancestry eQTL and single-nucleus multiomic analyses
FJA Leblanc, X Jin, K Kang, CJM Lee, J Xu, L Xuan, W Ma, H Belhaj, ...
iScience 27 (9), 2024
2024
TRIM35: A Proposed Gateway to p53-Induced Heart Failure Pathogenesis
CJM Lee, RSY Foo
Circulation Research 135 (2), 314-316, 2024
2024
Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation
Y Zhu, M Ackers-Johnson, MK Shanmugam, LS Pakkiri, CL Drum, Y Chen, ...
Circulation 149 (23), 1833-1851, 2024
2024
Coordination of focal adhesion nanostructure and mechano-signaling drives cardiomyocyte differentiation
J Xiao, X Zhong, JW Ang, DCP Wong, CJM Lee, RSY Foo, ...
bioRxiv, 2023.11. 13.566796, 2023
2023
CTCF mediates the Activity-by-contact derived cis-regulatory hubs
M Lee, L Mangnier, CC Padilla, DP Lee, W Tan, PY Li, WH Zheng, L Gan, ...
bioRxiv, 2022.11. 04.515249, 2022
2022
BNIP‐2 Activation of Cellular Contractility Inactivates YAP for H9c2 Cardiomyoblast Differentiation (Adv. Sci. 31/2022)
DCP Wong, J Xiao, TW Chew, M Pan, CJM Lee, JW Ang, I Yow, ...
Advanced Science 9 (31), 2022
2022
P-067: Systematic functional characterization for loss of function events cooperating with TP53 loss in high-risk 17p13 (del) multiple myeloma
PJ Teoh, RDM Simoes, TH Chung, M Lee, R Foo, WJ Chng, C Mitsiades
Clinical Lymphoma Myeloma and Leukemia 22, S72, 2022
2022
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