Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes J Vandesompele, K De Preter, F Pattyn, B Poppe, N Van Roy, ... Genome biology 3, 1-12, 2002 | 21958 | 2002 |
RTPrimerDB: the real-time PCR primer and probe database F Pattyn, F Speleman, A De Paepe, J Vandesompele Nucleic acids research 31 (1), 122-123, 2003 | 302 | 2003 |
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas F Westermann, D Muth, A Benner, T Bauer, KO Henrich, A Oberthuer, ... Genome biology 9, 1-14, 2008 | 295 | 2008 |
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice LC Heukamp, T Thor, A Schramm, K De Preter, C Kumps, B De Wilde, ... Science translational medicine 4 (141), 141ra91-141ra91, 2012 | 206 | 2012 |
RDML: structured language and reporting guidelines for real-time quantitative PCR data S Lefever, J Hellemans, F Pattyn, DR Przybylski, C Taylor, R Geurts, ... Nucleic acids research 37 (7), 2065-2069, 2009 | 194 | 2009 |
Single-nucleotide polymorphisms and other mismatches reduce performance of quantitative PCR assays S Lefever, F Pattyn, J Hellemans, J Vandesompele Clinical chemistry 59 (10), 1470-1480, 2013 | 193 | 2013 |
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours P Mestdagh, E Fredlund, F Pattyn, A Rihani, T Van Maerken, J Vermeulen, ... Oncogene 29 (24), 3583-3592, 2010 | 180 | 2010 |
RTPrimerDB: the portal for real-time PCR primers and probes S Lefever, J Vandesompele, F Speleman, F Pattyn Nucleic acids research 37 (suppl_1), D942-D945, 2009 | 179 | 2009 |
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors P Mestdagh, E Fredlund, F Pattyn, JH Schulte, D Muth, J Vermeulen, ... Oncogene 29 (9), 1394-1404, 2010 | 150 | 2010 |
RTPrimerDB: the real-time PCR primer and probe database, major update 2006 F Pattyn, P Robbrecht, A De Paepe, F Speleman, J Vandesompele Nucleic Acids Research 34 (suppl_1), D684-D688, 2006 | 150 | 2006 |
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays B Menten, F Pattyn, K De Preter, P Robbrecht, E Michels, K Buysse, ... BMC bioinformatics 6, 1-9, 2005 | 115 | 2005 |
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma M Lodrini, I Oehme, C Schroeder, T Milde, MC Schier, A Kopp-Schneider, ... Nucleic acids research 41 (12), 6018-6033, 2013 | 110 | 2013 |
Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for … B D'haene, C Attanasio, D Beysen, J Dostie, E Lemire, P Bouchard, ... PLoS genetics 5 (6), e1000522, 2009 | 109 | 2009 |
The microRNA body map: dissecting microRNA function through integrative genomics P Mestdagh, S Lefever, F Pattyn, D Ridzon, E Fredlund, A Fieuw, ... Nucleic acids research 39 (20), e136-e136, 2011 | 100 | 2011 |
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma J Hoebeeck, E Michels, F Pattyn, V Combaret, J Vermeulen, N Yigit, ... Cancer letters 273 (2), 336-346, 2009 | 84 | 2009 |
Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform S De Keulenaer, J Hellemans, S Lefever, JP Renard, J De Schrijver, ... BMC medical genomics 5, 1-8, 2012 | 76 | 2012 |
Focal DNA copy number changes in neuroblastoma target MYCN regulated genes C Kumps, A Fieuw, P Mestdagh, B Menten, S Lefever, F Pattyn, ... PloS one 8 (1), e52321, 2013 | 68 | 2013 |
Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation A Edsjö, H Nilsson, J Vandesompele, J Karlsson, F Pattyn, LA Culp, ... Laboratory investigation 84 (4), 406-417, 2004 | 66 | 2004 |
The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy N Van Roy, K De Preter, J Hoebeeck, T Van Maerken, F Pattyn, ... Genome medicine 1, 1-11, 2009 | 63 | 2009 |
Dickkopf‐3 is regulated by the MYCN‐induced miR‐17‐92 cluster in neuroblastoma S De Brouwer, P Mestdagh, I Lambertz, F Pattyn, A De Paepe, ... International journal of cancer 130 (11), 2591-2598, 2012 | 61 | 2012 |