| Response of a concentrated monoclonal antibody formulation to high shear JS Bee, JL Stevenson, B Mehta, J Svitel, J Pollastrini, R Platz, E Freund, ... Biotechnology and bioengineering 103 (5), 936-943, 2009 | 223 | 2009 |
| Protein aggregation and particle formation in prefilled glass syringes A Gerhardt, NR Mcgraw, DK Schwartz, JS Bee, JF Carpenter, ... Journal of pharmaceutical sciences 103 (6), 1601-1612, 2014 | 196 | 2014 |
| Effects of surfaces and leachables on the stability of biopharmaceuticals JS Bee, TW Randolph, JF Carpenter, SM Bishop, MN Dimitrova Journal of Pharmaceutical Sciences, 2011 | 184 | 2011 |
| Monoclonal antibody interactions with micro‐and nanoparticles: Adsorption, aggregation, and accelerated stress studies JS Bee, D Chiu, S Sawicki, JL Stevenson, K Chatterjee, E Freund, ... Journal of pharmaceutical sciences 98 (9), 3218-3238, 2009 | 181 | 2009 |
| Production of particles of therapeutic proteins at the air–water interface during compression/dilation cycles JS Bee, DK Schwartz, S Trabelsi, E Freund, JL Stevenson, JF Carpenter, ... Soft Matter 8 (40), 10329-10335, 2012 | 135 | 2012 |
| Aggregation of a monoclonal antibody induced by adsorption to stainless steel JS Bee, M Davis, E Freund, JF Carpenter, TW Randolph Biotechnology and bioengineering 105 (1), 121-129, 2010 | 131 | 2010 |
| Precipitation of a monoclonal antibody by soluble tungsten JS Bee, SA Nelson, E Freund, JF Carpenter, TW Randolph Journal of pharmaceutical sciences 98 (9), 3290-3301, 2009 | 121 | 2009 |
| Gelation of a monoclonal antibody at the silicone oil–water interface and subsequent rupture of the interfacial gel results in aggregation and particle formation SB Mehta, R Lewus, JS Bee, TW Randolph, JF Carpenter Journal of pharmaceutical sciences 104 (4), 1282-1290, 2015 | 104 | 2015 |
| Trace levels of the CHO host cell protease cathepsin D caused particle formation in a monoclonal antibody product JS Bee, L Tie, D Johnson, MN Dimitrova, KC Jusino, CD Afdahl Biotechnology Progress 31 (5), 1360-1369, 2015 | 86 | 2015 |
| Ionic strength affects tertiary structure and aggregation propensity of a monoclonal antibody adsorbed to silicone oil–water interfaces A Gerhardt, K Bonam, JS Bee, JF Carpenter, TW Randolph Journal of pharmaceutical sciences 102 (2), 429-440, 2013 | 86 | 2013 |
| Submicron size particles of a murine monoclonal antibody are more immunogenic than soluble oligomers or micron size particles upon subcutaneous administration in mice G Kijanka, JS Bee, SA Korman, Y Wu, LK Roskos, MA Schenerman, ... Journal of pharmaceutical sciences 107 (11), 2847-2859, 2018 | 71 | 2018 |
| Variable dimensionality in the uranium fluoride/2-methyl-piperazine system: Synthesis and structures of UFO-5,-6, and-7; Zero-, one-, and two-dimensional materials with … RJ Francis, PS Halasyamani, JS Bee, D O'Hare Journal of the American Chemical Society 121 (7), 1999 | 71 | 1999 |
| Computational fluid dynamics (CFD) insights into agitation stress methods in biopharmaceutical development G Bai, JS Bee, JG Biddlecombe, Q Chen, WT Leach International Journal of Pharmaceutics, 2011 | 69 | 2011 |
| Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody V Oganesyan, L Peng, JS Bee, J Li, SR Perry, F Comer, L Xu, K Cook, ... Journal of Biological Chemistry 293 (22), 8439-8448, 2018 | 61 | 2018 |
| The future of protein particle characterization and understanding its potential to diminish the immunogenicity of biopharmaceuticals: a shared perspective JS Bee, TJ Goletz, JA Ragheb Journal of pharmaceutical sciences 101 (10), 3580-3585, 2012 | 59 | 2012 |
| Partial unfolding of a monoclonal antibody: role of a single domain in driving protein aggregation SB Mehta, JS Bee, TW Randolph, JF Carpenter Biochemistry 53 (20), 3367-3377, 2014 | 41 | 2014 |
| Analytical characterization of coformulated antibodies as combination therapy J Kim, YJ Kim, M Cao, N De Mel, K Miller, JS Bee, J Wang, X Wang, ... MAbs 12 (1), 1738691, 2020 | 27 | 2020 |
| Identification of an IgG CDR sequence contributing to co‐purification of the host cell protease cathepsin D JS Bee, LAM Machiesky, L Peng, KC Jusino, M Dickson, J Gill, D Johnson, ... Biotechnology progress 33 (1), 140-145, 2017 | 27 | 2017 |
| Targeted Fcγ receptor (FcγR)-mediated clearance by a biparatopic bispecific antibody S Kasturirangan, GJ Rainey, L Xu, X Wang, A Portnoff, T Chen, ... Journal of Biological Chemistry 292 (10), 4361-4370, 2017 | 26 | 2017 |
| Fate of multimeric oligomers, submicron, and micron size aggregates of monoclonal antibodies upon subcutaneous injection in mice G Kijanka, JS Bee, SM Bishop, I Que, C Löwik, W Jiskoot Journal of pharmaceutical sciences 105 (5), 1693-1704, 2016 | 22 | 2016 |
TW RandolphDepartment of Chemical and Biological Engineering, University of Colorado, BoulderVerified email at colorado.edu