| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2368 | 2019 |
| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1159 | 2022 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 946 | 2017 |
| Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study EM Reiman, JF Arboleda-Velasquez, YT Quiroz, MJ Huentelman, ... Nature communications 11 (1), 667, 2020 | 330 | 2020 |
| Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation JC Bis, X Jian, BW Kunkle, Y Chen, KL Hamilton-Nelson, WS Bush, ... Molecular psychiatry 25 (8), 1859-1875, 2020 | 248 | 2020 |
| Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis BW Kunkle, M Schmidt, HU Klein, AC Naj, KL Hamilton-Nelson, ... JAMA neurology 78 (1), 102-113, 2021 | 194 | 2021 |
| Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE … BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nat Genet 51 (3), 414-430, 2019 | 80 | 2019 |
| Late-onset Alzheimer disease risk variants mark brain regulatory loci M Allen, M Kachadoorian, MM Carrasquillo, A Karhade, L Manly, ... Neurology: Genetics 1 (2), e15, 2015 | 74 | 2015 |
| HIPPIE: a high-throughput identification pipeline for promoter interacting enhancer elements YC Hwang, CF Lin, O Valladares, J Malamon, PP Kuksa, Q Zheng, ... Bioinformatics 31 (8), 1290-1292, 2015 | 67 | 2015 |
| Association of rare coding mutations with Alzheimer disease and other dementias among adults of European ancestry D Patel, J Mez, BN Vardarajan, L Staley, J Chung, X Zhang, JJ Farrell, ... JAMA network open 2 (3), e191350-e191350, 2019 | 62 | 2019 |
| Survival benefit of living-donor liver transplant WE Jackson, JS Malamon, B Kaplan, JL Saben, JD Schold, JJ Pomposelli, ... JAMA surgery 157 (10), 926-932, 2022 | 61 | 2022 |
| Early-onset Alzheimer disease and candidate risk genes involved in endolysosomal transport BW Kunkle, BN Vardarajan, AC Naj, PL Whitehead, S Rolati, S Slifer, ... JAMA neurology 74 (9), 1113-1122, 2017 | 56 | 2017 |
| Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease BN Vardarajan, S Barral, J Jaworski, GW Beecham, E Blue, G Tosto, ... Annals of clinical and translational neurology 5 (4), 406-417, 2018 | 46 | 2018 |
| Analysis of whole-exome sequencing data for Alzheimer disease stratified by APOE genotype Y Ma, GR Jun, X Zhang, J Chung, AC Naj, Y Chen, C Bellenguez, ... JAMA neurology 76 (9), 1099-1108, 2019 | 42 | 2019 |
| A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease X Zhang, C Zhu, G Beecham, BN Vardarajan, Y Ma, D Lancour, JJ Farrell, ... Alzheimer's & Dementia 15 (3), 441-452, 2019 | 39 | 2019 |
| Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, AC Naj, A Boland, ... BioRxiv, 294629, 2018 | 36 | 2018 |
| Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project AC Naj, H Lin, BN Vardarajan, S White, D Lancour, Y Ma, M Schmidt, ... Genomics 111 (4), 808-818, 2019 | 31 | 2019 |
| Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease GW Beecham, B Vardarajan, E Blue, W Bush, J Jaworski, S Barral, ... Neurology: Genetics 4 (6), e286, 2018 | 28 | 2018 |
| NIAGADS: the NIA genetics of Alzheimer's disease data storage site A Kuzma, O Valladares, R Cweibel, E Greenfest‐Allen, DM Childress, ... Alzheimer's & Dementia 12 (11), 1200-1203, 2016 | 28 | 2016 |
| Genetic variation in genes underlying diverse dementias may explain a small proportion of cases in the Alzheimer’s Disease Sequencing Project EE Blue, JC Bis, MO Dorschner, DW Tsuang, SM Barral, G Beecham, ... Dementia and geriatric cognitive disorders 45 (1-2), 1-17, 2018 | 25 | 2018 |
Li-San WangUniversity of PennsylvaniaVerified email at upenn.edu