The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery R Laing, T Kikuchi, A Martinelli, IJ Tsai, RN Beech, E Redman, N Holroyd, ... Genome biology 14, 1-16, 2013 | 368 | 2013 |
RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects P Geldhof, A Visser, D Clark, G Saunders, C Britton, J Gilleard, ... Parasitology 134 (5), 609-619, 2006 | 189 | 2006 |
Testing the efficacy of RNA interference in Haemonchus contortus P Geldhof, L Murray, A Couthier, JS Gilleard, G McLauchlan, DP Knox, ... International journal for parasitology 36 (7), 801-810, 2006 | 162 | 2006 |
Cathepsin L is essential for embryogenesis and development ofCaenorhabditis elegans S Hashmi, C Britton, J Liu, DB Guiliano, Y Oksov, S Lustigman Journal of Biological Chemistry 277 (5), 3477-3486, 2002 | 140 | 2002 |
RNA interference in parasitic nematodes of animals: a reality check? DP Knox, P Geldhof, A Visser, C Britton Trends in parasitology 23 (3), 105-107, 2007 | 133 | 2007 |
Refugia and anthelmintic resistance: concepts and challenges JE Hodgkinson, RM Kaplan, F Kenyon, ER Morgan, AW Park, S Paterson, ... International Journal for Parasitology: Drugs and Drug Resistance 10, 51-57, 2019 | 124 | 2019 |
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm SR Doyle, A Tracey, R Laing, N Holroyd, D Bartley, W Bazant, H Beasley, ... Communications biology 3 (1), 656, 2020 | 118 | 2020 |
A cathepsin L protease essential for Caenorhabditis elegans embryogenesis is functionally conserved in parasitic nematodes C Britton, L Murray Molecular and biochemical parasitology 122 (1), 21-33, 2002 | 114 | 2002 |
Factors affecting susceptibility to RNA interference in Haemonchus contortus and in vivo silencing of an H11 aminopeptidase gene B Samarasinghe, DP Knox, C Britton International journal for parasitology 41 (1), 51-59, 2011 | 94 | 2011 |
microRNAs of parasitic helminths–Identification, characterization and potential as drug targets C Britton, AD Winter, V Gillan, E Devaney International Journal for Parasitology: Drugs and Drug Resistance 4 (2), 85-94, 2014 | 87 | 2014 |
Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel AD Winter, W Weir, M Hunt, M Berriman, JS Gilleard, E Devaney, C Britton BMC genomics 13, 1-19, 2012 | 86 | 2012 |
Using Caenorhabditis elegans for functional analysis of genes of parasitic nematodes C Britton, L Murray International Journal for Parasitology 36 (6), 651-659, 2006 | 84 | 2006 |
Cathepsin L protease (CPL-1) is essential for yolk processing during embryogenesis in Caenorhabditis elegans C Britton, L Murray Journal of Cell Science 117 (21), 5133-5143, 2004 | 79 | 2004 |
Characterization and comparative analysis of the complete Haemonchus contortus β-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes GI Saunders, JD Wasmuth, R Beech, R Laing, M Hunt, H Naghra, ... International journal for parasitology 43 (6), 465-475, 2013 | 75 | 2013 |
Regulation of the Caenorhabditis elegans gut cysteine protease gene cpr-1: requirement for GATA motifs C Britton, JH McKerrow, IL Johnstone Journal of molecular biology 283 (1), 15-27, 1998 | 69 | 1998 |
Identification of promoter elements of parasite nematode genes in transgenic Caenorhabditis elegans C Britton, DL Redmond, DP Knox, JH McKerrow, JD Barry Molecular and Biochemical Parasitology 103 (2), 171-181, 1999 | 68 | 1999 |
microRNAs: a role in drug resistance in parasitic nematodes? E Devaney, AD Winter, C Britton Trends in parasitology 26 (9), 428-433, 2010 | 65 | 2010 |
A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry SR Doyle, R Laing, DJ Bartley, C Britton, U Chaudhry, JS Gilleard, ... Genome Biology and Evolution 10 (2), 396-409, 2018 | 64 | 2018 |
Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans B Roberts, A Antonopoulos, SM Haslam, AJ Dicker, TN McNeilly, ... Veterinary research 44, 1-15, 2013 | 63 | 2013 |
Functional genomics tools for Haemonchus contortus and lessons from other helminths C Britton, B Roberts, ND Marks Advances in parasitology 93, 599-623, 2016 | 51 | 2016 |