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Rachel Queen
Rachel Queen
Verified email at newcastle.ac.uk
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SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
Nature medicine 26 (5), 681-687, 2020
27952020
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
3152021
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis
O Govaere, S Cockell, D Tiniakos, R Queen, R Younes, M Vacca, ...
Science translational medicine 12 (572), eaba4448, 2020
2742020
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and …
C Muus, MD Luecken, G Eraslan, A Waghray, G Heimberg, L Sikkema, ...
BioRxiv, 2020.04. 19.049254, 2020
2592020
Differential IRF8 transcription factor requirement defines two pathways of dendritic cell development in humans
U Cytlak, A Resteu, S Pagan, K Green, P Milne, S Maisuria, D McDonald, ...
Immunity 53 (2), 353-370. e8, 2020
1932020
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface
J Collin, R Queen, D Zerti, B Dorgau, M Georgiou, I Djidrovski, R Hussain, ...
The ocular surface 19, 190-200, 2021
1462021
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells
J Collin, R Queen, D Zerti, S Bojic, B Dorgau, N Moyse, MM Molina, ...
The ocular surface 21, 279-298, 2021
1242021
Deconstructing retinal organoids: single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina
J Collin, R Queen, D Zerti, B Dorgau, R Hussain, J Coxhead, S Cockell, ...
Stem Cells 37 (5), 593-598, 2019
1122019
Blood and immune development in human fetal bone marrow and Down syndrome
L Jardine, S Webb, I Goh, M Quiroga Londoño, G Reynolds, M Mather, ...
Nature 598 (7880), 327-331, 2021
912021
Systematic comparison of retinal organoid differentiation from human pluripotent stem cells reveals stage specific, cell line, and methodological differences
CB Mellough, J Collin, R Queen, G Hilgen, B Dorgau, D Zerti, ...
Stem cells translational medicine 8 (7), 694-706, 2019
862019
HCA Lung Biological Network
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells …, 2020
812020
CRX expression in pluripotent stem cell-derived photoreceptors marks a transplantable subpopulation of early cones
J Collin, D Zerti, R Queen, T Santos-Ferreira, R Bauer, J Coxhead, ...
Stem Cells 37 (5), 609-622, 2019
662019
In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?
L Armstrong, J Collin, I Mostafa, R Queen, FC Figueiredo, M Lako
Stem Cells Translational Medicine 10 (7), 976-986, 2021
412021
Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance
K Johnson, PJ Leary, O Govaere, MJ Barter, SH Charlton, SJ Cockell, ...
JHEP Reports 4 (2), 100409, 2022
382022
Human retinal organoids provide a suitable tool for toxicological investigations: a comprehensive validation using drugs and compounds affecting the retina
B Dorgau, M Georgiou, A Chaudhary, M Moya-Molina, J Collin, R Queen, ...
Stem Cells Translational Medicine 11 (2), 159-177, 2022
292022
CD200 expression marks a population of quiescent limbal epithelial stem cells with holoclone forming ability
S Bojic, D Hallam, N Alcada, A Ghareeb, R Queen, S Pervinder, H Buck, ...
Stem Cells 36 (11), 1723-1735, 2018
282018
Understanding the complexity of retina and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future …
D Zerti, J Collin, R Queen, SJ Cockell, M Lako
Current eye research 45 (3), 385-396, 2020
262020
Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumors by single cell sequencing—opening …
J Collin, R Queen, D Zerti, DH Steel, C Bowen, M Parulekar, M Lako
Investigative ophthalmology & visual science 62 (6), 18-18, 2021
252021
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell …
A Rozanska, R Cerna-Chavez, R Queen, J Collin, D Zerti, B Dorgau, ...
Stem Cells Translational Medicine 11 (4), 415-433, 2022
232022
Mitochondrial DNA sequence context in the penetrance of mitochondrial t-RNA mutations: a study across multiple lineages with diagnostic implications
RA Queen, JS Steyn, P Lord, JL Elson
PLoS One 12 (11), e0187862, 2017
222017
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