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Patrick Ball
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Identification of novel nitroreductases from Bacillus cereus and their interaction with the CB1954 prodrug
VV Gwenin, P Poornima, J Halliwell, P Ball, G Robinson, CD Gwenin
Biochemical Pharmacology 98 (3), 392-402, 2015
242015
Time dependent HPLC analysis of the product ratio of enzymatically reduced prodrug CB1954 by a modified and immobilised nitroreductase
P Ball, E Thompson, S Anderson, V Gwenin, C Gwenin
European Journal of Pharmaceutical Sciences 127, 217-224, 2019
132019
Cell-penetrating peptides as a tool for the cellular uptake of a genetically modified nitroreductase for use in directed enzyme prodrug therapy
SD Anderson, RJ Hobbs, VV Gwenin, P Ball, LA Bennie, JA Coulter, ...
Journal of functional biomaterials 10 (4), 45, 2019
72019
The YfkO nitroreductase from bacillus licheniformis on gold-coated superparamagnetic nanoparticles: towards a novel directed enzyme prodrug therapy approach
P Ball, R Hobbs, S Anderson, E Thompson, V Gwenin, C Von Ruhland, ...
Pharmaceutics 13 (4), 517, 2021
42021
Evaluation of two xenobiotic reductases from Pseudomonas putida for their suitability for magnetic nanoparticle‐directed enzyme prodrug therapy as a novel …
P Ball, J Halliwell, S Anderson, V Gwenin, C Gwenin
Microbiologyopen 9 (10), e1110, 2020
42020
The dinitrobenzamide mustard prodrugs, PR-104A and SN27686, for use in a novel MNDEPT cancer prodrug therapy approach
P Ball, E Thompson, S Anderson, V Gwenin, A Ashoorzadeh, J Smaill, ...
Bioscience Reports 43 (4), BSR20230627, 2023
2023
Identification and testing of enzymes and prodrugs for use in directed enzyme prodrug therapy strategies for the treatment of cancer
P Ball
PQDT-UK & Ireland, 2019
2019
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