| Neurodegenerative disease and the NLRP3 inflammasome JA Holbrook, HH Jarosz-Griffiths, E Caseley, S Lara-Reyna, JA Poulter, ... Frontiers in pharmacology 12, 643254, 2021 | 138 | 2021 |
| Moving towards a systems-based classification of innate immune-mediated diseases S Savic, EA Caseley, MF McDermott Nature Reviews Rheumatology 16 (4), 222-237, 2020 | 73 | 2020 |
| Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers EA Caseley, SP Muench, S Roger, HJ Mao, SA Baldwin, LH Jiang International journal of molecular sciences 15 (8), 13344-13371, 2014 | 64 | 2014 |
| Structural basis for the functional properties of the P2X7 receptor for extracellular ATP LH Jiang, EA Caseley, SP Muench, S Roger Purinergic Signalling 17 (3), 331-344, 2021 | 41 | 2021 |
| Biological impact of silicon nitride for orthopaedic applications: role of particle size, surface composition and donor variation S Lal, EA Caseley, RM Hall, JL Tipper Scientific reports 8 (1), 9109, 2018 | 40 | 2018 |
| ATP-induced P2X receptor-dependent large pore formation: how much do we know? L Wei, E Caseley, D Li, LH Jiang Frontiers in pharmacology 7, 5, 2016 | 39 | 2016 |
| Inflammasome inhibition under physiological and pharmacological conditions EA Caseley, JA Poulter, F Rodrigues, ... Genes & Immunity 21 (4), 211-223, 2020 | 32 | 2020 |
| Docking of competitive inhibitors to the P2X7 receptor family reveals key differences responsible for changes in response between rat and human EA Caseley, SP Muench, SA Baldwin, K Simmons, CW Fishwick, ... Bioorganic & medicinal chemistry letters 25 (16), 3164-3167, 2015 | 28 | 2015 |
| Fluorescence spectroscopy analysis of the bacteria–mineral interface: Adsorption of lipopolysaccharides to silica and alumina F El-Taboni, E Caseley, M Katsikogianni, L Swanson, T Swift, ... Langmuir 36 (7), 1623-1632, 2020 | 27 | 2020 |
| Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists EA Caseley, SP Muench, CW Fishwick, LH Jiang Biochemical pharmacology 116, 130-139, 2016 | 27 | 2016 |
| Inflammasome activation: from molecular mechanisms to autoinflammation S Lara‐Reyna, EA Caseley, J Topping, F Rodrigues, J Jimenez Macias, ... Clinical & Translational Immunology 11 (7), e1404, 2022 | 24 | 2022 |
| Immunome project consortium for autoinflammatory disorders (ImmunAID), McDermott MF. Inflammasome inhibition under physiological and pharmacological conditions EA Caseley, JA Poulter, F Rodrigues Genes Immun 21, 211-223, 2020 | 15 | 2020 |
| An atypical autoinflammatory disease due to an LRR domain NLRP3 mutation enhancing binding to NEK7 EA Caseley, S Lara-Reyna, JA Poulter, J Topping, C Carter, F Nadat, ... Journal of Clinical Immunology, 1-13, 2022 | 12 | 2022 |
| Escape from adamantane: scaffold optimization of novel P2X7 antagonists featuring complex polycycles M Barniol-Xicota, SH Kwak, SD Lee, E Caseley, E Valverde, LH Jiang, ... Bioorganic & Medicinal Chemistry Letters 27 (4), 759-763, 2017 | 12 | 2017 |
| Conformational changes during human P2X7 receptor activation examined by structural modelling and cysteine-based cross-linking studies EA Caseley, SP Muench, LH Jiang Purinergic Signalling 13 (1), 135-141, 2017 | 9 | 2017 |
| Leveraging the ATP‐P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications Y Yin, L Wei, EA Caseley, O Lopez‐Charcas, Y Wei, D Li, SP Muench, ... Medicinal Research Reviews 43 (5), 1346-1373, 2023 | 7 | 2023 |
| Branched amphotericin functional poly(N-isopropyl acrylamide): an antifungal polymer T Swift, E Caseley, A Pinnock, J Shepherd, N Shivshetty, P Garg, ... Royal Society Open Science 8 (1), 201655, 2021 | 5 | 2021 |
| Contribution of Val/Ile87 residue in the extracellular domain in agonist-induced current responses of the human and rat P2X7 receptors EA Caseley, SP Muench, LH Jiang Purinergic Signalling 16 (4), 485-490, 2020 | 5 | 2020 |
| Drosophila expressing mutant human KCNT1 transgenes make an effective tool for targeted drug screening in a whole animal model of KCNT1-epilepsy R Hussain, CX Lim, Z Shaukat, A Islam, EA Caseley, JD Lippiat, ... Scientific reports 14 (1), 3357, 2024 | 3 | 2024 |
| Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modeling and site‐directed mutagenesis EA Caseley, SP Muench, LH Jiang Proteins: Structure, Function, and Bioinformatics 90 (3), 619-624, 2022 | 2 | 2022 |