Membrane proteins bind lipids selectively to modulate their structure and function A Laganowsky, E Reading, TM Allison, MB Ulmschneider, MT Degiacomi, ... Nature 510 (7503), 172-175, 2014 | 824 | 2014 |
Atomic view of a toxic amyloid small oligomer A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ... Science 335 (6073), 1228-1231, 2012 | 614 | 2012 |
Molecular basis for amyloid-β polymorphism JP Colletier, A Laganowsky, M Landau, M Zhao, AB Soriaga, ... Proceedings of the National Academy of Sciences 108 (41), 16938-16943, 2011 | 453 | 2011 |
Mass spectrometry of intact membrane protein complexes A Laganowsky, E Reading, JTS Hopper, CV Robinson Nature protocols 8 (4), 639-651, 2013 | 435 | 2013 |
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function A Laganowsky, JLP Benesch, M Landau, L Ding, MR Sawaya, D Cascio, ... Protein science 19 (5), 1031-1043, 2010 | 325 | 2010 |
Structure of a designed protein cage that self-assembles into a highly porous cube YT Lai, E Reading, GL Hura, KL Tsai, A Laganowsky, FJ Asturias, ... Nature chemistry 6 (12), 1065-1071, 2014 | 305 | 2014 |
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1 B Zhao, F Du, P Xu, C Shu, B Sankaran, SL Bell, M Liu, Y Lei, X Gao, X Fu, ... Nature 569 (7758), 718-722, 2019 | 299 | 2019 |
Towards a pharmacophore for amyloid M Landau, MR Sawaya, KF Faull, A Laganowsky, L Jiang, SA Sievers, ... PLoS biology 9 (6), e1001080, 2011 | 244 | 2011 |
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity GKA Hochberg, H Ecroyd, C Liu, D Cox, D Cascio, MR Sawaya, ... Proceedings of the National Academy of Sciences 111 (16), E1562-E1570, 2014 | 222 | 2014 |
Detergent-free mass spectrometry of membrane protein complexes JTS Hopper, YTC Yu, D Li, A Raymond, M Bostock, I Liko, V Mikhailov, ... Nature methods 10 (12), 1206-1208, 2013 | 185 | 2013 |
Quantifying the stabilizing effects of protein–ligand interactions in the gas phase TM Allison, E Reading, I Liko, AJ Baldwin, A Laganowsky, CV Robinson Nature communications 6 (1), 8551, 2015 | 182 | 2015 |
Determining membrane protein–lipid binding thermodynamics using native mass spectrometry X Cong, Y Liu, W Liu, X Liang, DH Russell, A Laganowsky Journal of the American Chemical Society 138 (13), 4346-4349, 2016 | 158 | 2016 |
The role of the detergent micelle in preserving the structure of membrane proteins in the gas phase E Reading, I Liko, TM Allison, JLP Benesch, A Laganowsky, CV Robinson Angewandte Chemie International Edition 54 (15), 4577-4581, 2015 | 157 | 2015 |
Origin of complexity in haemoglobin evolution AS Pillai, SA Chandler, Y Liu, AV Signore, CR Cortez-Romero, ... Nature 581 (7809), 480-485, 2020 | 124 | 2020 |
Melting proteins: evidence for multiple stable structures upon thermal denaturation of native ubiquitin from ion mobility spectrometry-mass spectrometry measurements TJ El-Baba, DW Woodall, SA Raab, DR Fuller, A Laganowsky, ... Journal of the American Chemical Society 139 (18), 6306-6309, 2017 | 120 | 2017 |
A hydrophobic ratchet entrenches molecular complexes GKA Hochberg, Y Liu, EG Marklund, BPH Metzger, A Laganowsky, ... Nature 588 (7838), 503-508, 2020 | 106 | 2020 |
Allostery revealed within lipid binding events to membrane proteins JW Patrick, CD Boone, W Liu, GM Conover, Y Liu, X Cong, A Laganowsky Proceedings of the National Academy of Sciences 115 (12), 2976-2981, 2018 | 103 | 2018 |
Dynamical coupling of intrinsically disordered proteins and their hydration water: comparison with folded soluble and membrane proteins FX Gallat, A Laganowsky, K Wood, F Gabel, L Van Eijck, J Wuttke, ... Biophysical journal 103 (1), 129-136, 2012 | 94 | 2012 |
The effect of detergent, temperature, and lipid on the oligomeric state of MscL constructs: insights from mass spectrometry E Reading, TA Walton, I Liko, MT Marty, A Laganowsky, DC Rees, ... Chemistry & biology 22 (5), 593-603, 2015 | 93 | 2015 |
Fourier transform-ion mobility-orbitrap mass spectrometer: a next-generation instrument for native mass spectrometry ML Poltash, JW McCabe, M Shirzadeh, A Laganowsky, BH Clowers, ... Analytical chemistry 90 (17), 10472-10478, 2018 | 92 | 2018 |