Articles with public access mandates - Simon PhillipsLearn more
Not available anywhere: 2
The structural basis of Holliday junction resolution by T7 endonuclease I
JM Hadden, AC Déclais, SB Carr, DMJ Lilley, SEV Phillips
Nature 449 (7162), 621-624, 2007
Mandates: Cancer Research UK
Rise of the molecular machines.
K Luger, SEV Phillips
Current opinion in structural biology 20 (1), 70-72, 2010
Mandates: Howard Hughes Medical Institute
Available somewhere: 22
Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy
S Uppal, CP Diggle, IM Carr, CWG Fishwick, M Ahmed, GH Ibrahim, ...
Nature genetics 40 (6), 789-793, 2008
Mandates: Cancer Research UK
Mechanism of hydrogen activation by [NiFe] hydrogenases
RM Evans, EJ Brooke, SAM Wehlin, E Nomerotskaia, F Sargent, SB Carr, ...
Nature chemical biology 12 (1), 46-50, 2016
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment
CE Quevedo, A Cruz-Migoni, N Bery, A Miller, T Tanaka, D Petch, ...
Nature communications 9 (1), 3169, 2018
Mandates: UK Biotechnology and Biological Sciences Research Council, Blood Cancer UK …
Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds
A Cruz-Migoni, P Canning, CE Quevedo, CJR Bataille, N Bery, A Miller, ...
Proceedings of the National Academy of Sciences 116 (7), 2545-2550, 2019
Mandates: Blood Cancer UK, UK Engineering and Physical Sciences Research Council, UK …
Revealing the density of encoded functions in a viral RNA
N Patel, EC Dykeman, RHA Coutts, GP Lomonossoff, DJ Rowlands, ...
Proceedings of the National Academy of Sciences 112 (7), 2227-2232, 2015
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Cross-link formation of the cysteine 228− tyrosine 272 catalytic cofactor of galactose oxidase does not require dioxygen
MS Rogers, R Hurtado-Guerrero, SJ Firbank, MA Halcrow, DM Dooley, ...
Biochemistry 47 (39), 10428-10439, 2008
Mandates: US National Institutes of Health
BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions
N Bery, A Cruz-Migoni, CJR Bataille, CE Quevedo, H Tulmin, A Miller, ...
Elife 7, e37122, 2018
Mandates: Blood Cancer UK, UK Medical Research Council, Wellcome Trust
5-Formylcytosine does not change the global structure of DNA
JS Hardwick, D Ptchelkine, AH El-Sagheer, I Tear, D Singleton, ...
Nature structural & molecular biology 24 (6), 544-552, 2017
Mandates: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Rewriting nature’s assembly manual for a ssRNA virus
N Patel, E Wroblewski, G Leonov, SEV Phillips, R Tuma, R Twarock, ...
Proceedings of the National Academy of Sciences 114 (46), 12255-12260, 2017
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis
AD Daniels, I Campeotto, MW Van der Kamp, AH Bolt, CH Trinh, ...
ACS chemical biology 9 (4), 1025-1032, 2014
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Importance of the Active Site “Canopy” Residues in an O2-Tolerant [NiFe]-Hydrogenase
EJ Brooke, RM Evans, STA Islam, GM Roberts, SAM Wehlin, SB Carr, ...
Biochemistry 56 (1), 132-142, 2017
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Structural insights into substrate specificity in variants of N-acetylneuraminic acid lyase produced by directed evolution
I Campeotto, AH Bolt, TA Harman, C Dennis, CH Trinh, SEV Phillips, ...
Journal of molecular biology 404 (1), 56-69, 2010
Mandates: US National Institutes of Health
Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging
D Ptchelkine, A Gillum, T Mochizuki, S Lucas-Staat, Y Liu, M Krupovic, ...
Nature communications 8 (1), 1436, 2017
Mandates: UK Medical Research Council, Wellcome Trust, European Commission
Structures of replication initiation proteins from staphylococcal antibiotic resistance plasmids reveal protein asymmetry and flexibility are necessary for replication
SB Carr, SEV Phillips, CD Thomas
Nucleic Acids Research 44 (5), 2417-2428, 2016
Mandates: UK Medical Research Council, Wellcome Trust
Hydrogen activation by [NiFe]-hydrogenases
SB Carr, RM Evans, EJ Brooke, SAM Wehlin, E Nomerotskaia, F Sargent, ...
Biochemical Society Transactions 44 (3), 863-868, 2016
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
A versatile strategy for production of membrane proteins with diverse topologies: application to investigation of bacterial homologues of human divalent metal ion and …
C Ma, Z Hao, G Huysmans, A Lesiuk, P Bullough, Y Wang, M Bartlam, ...
PLoS One 10 (11), e0143010, 2015
Mandates: Canadian Cancer Society, Canadian Institutes of Health Research, National …
Pathological macromolecular crystallographic data affected by twinning, partial-disorder and exhibiting multiple lattices for testing of data processing and refinement tools
I Campeotto, A Lebedev, AMM Schreurs, LMJ Kroon-Batenburg, E Lowe, ...
Scientific Reports 8 (1), 14876, 2018
Mandates: UK Medical Research Council, Wellcome Trust, UK Research & Innovation
Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein
L Bao, C Hannon, A Cruz-Mignoni, D Ptchelkine, M Sun, A Miller, ...
Scientific Reports 7 (1), 16869, 2017
Mandates: Blood Cancer UK, UK Medical Research Council, National Institute for Health …
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