The sequence of the human genome JC Venter, MD Adams, EW Myers, PW Li, RJ Mural, GG Sutton, HO Smith, ... science 291 (5507), 1304-1351, 2001 | 20299 | 2001 |
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ... Nature biotechnology 34 (8), 828-837, 2016 | 3452 | 2016 |
The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics R Huang, N Southall, Y Wang, A Yasgar, P Shinn, A Jadhav, DT Nguyen, ... Science translational medicine 3 (80), 80ps16-80ps16, 2011 | 436 | 2011 |
Unexplored therapeutic opportunities in the human genome TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ... Nature reviews Drug discovery 17 (5), 317-332, 2018 | 384 | 2018 |
Pharos: collating protein information to shed light on the druggable genome DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ... Nucleic acids research 45 (D1), D995-D1002, 2017 | 267 | 2017 |
The NCATS BioPlanet–an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics R Huang, I Grishagin, Y Wang, T Zhao, J Greene, JC Obenauer, D Ngan, ... Frontiers in pharmacology 10, 445, 2019 | 230 | 2019 |
Tox21Challenge to build predictive models of nuclear receptor and stress response pathways as mediated by exposure to environmental chemicals and drugs R Huang, M Xia, DT Nguyen, T Zhao, S Sakamuru, J Zhao, SA Shahane, ... Frontiers in Environmental Science 3, 85, 2016 | 207 | 2016 |
DrugCentral 2021 supports drug discovery and repositioning S Avram, CG Bologa, J Holmes, G Bocci, TB Wilson, DT Nguyen, ... Nucleic acids research 49 (D1), D1160-D1169, 2021 | 164 | 2021 |
CoMPARA: collaborative modeling project for androgen receptor activity K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ... Environmental Health Perspectives 128 (2), 027002, 2020 | 149 | 2020 |
Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3 … J Jiang, K Ghoreschi, F Deflorian, Z Chen, M Perreira, M Pesu, J Smith, ... Journal of medicinal chemistry 51 (24), 8012-8018, 2008 | 145 | 2008 |
High-frequency nano-optomechanical disk resonators in liquids E Gil-Santos, C Baker, DT Nguyen, W Hease, C Gomez, A Lemaître, ... Nature nanotechnology 10 (9), 810-816, 2015 | 142 | 2015 |
A specific mechanism for nonspecific activation in reporter-gene assays DS Auld, N Thorne, DT Nguyen, J Inglese ACS chemical biology 3 (8), 463-470, 2008 | 140 | 2008 |
DrugCentral 2018: an update O Ursu, J Holmes, CG Bologa, JJ Yang, SL Mathias, V Stathias, ... Nucleic acids research 47 (D1), D963-D970, 2019 | 135 | 2019 |
TCRD and Pharos 2021: mining the human proteome for disease biology TK Sheils, SL Mathias, KJ Kelleher, VB Siramshetty, DT Nguyen, ... Nucleic Acids Research 49 (D1), D1334-D1346, 2021 | 129 | 2021 |
Photoelastic coupling in gallium arsenide optomechanical disk resonators C Baker, W Hease, DT Nguyen, A Andronico, S Ducci, G Leo, I Favero Optics express 22 (12), 14072-14086, 2014 | 114 | 2014 |
A grid algorithm for high throughput fitting of dose-response curve data Y Wang, A Jadhav, N Southal, R Huang, DT Nguyen Current chemical genomics 4, 57, 2010 | 112 | 2010 |
CATMoS: collaborative acute toxicity modeling suite K Mansouri, AL Karmaus, J Fitzpatrick, G Patlewicz, P Pradeep, D Alberga, ... Environmental health perspectives 129 (4), 047013, 2021 | 100 | 2021 |
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk) AS Rosenthal, C Tanega, M Shen, BT Mott, JM Bougie, DT Nguyen, ... Bioorganic & medicinal chemistry letters 21 (10), 3152-3158, 2011 | 81 | 2011 |
Drug target ontology to classify and integrate drug discovery data Y Lin, S Mehta, H Küçük-McGinty, JP Turner, D Vidovic, M Forlin, A Koleti, ... Journal of biomedical semantics 8, 1-16, 2017 | 77 | 2017 |
Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening SJ Shukla, DT Nguyen, R MacArthur, A Simeonov, WJ Frazee, TM Hallis, ... Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA, 2010 | 70 | 2010 |