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Leveraging the UMLS as a Data Standard for Rare Disease Data normalization and harmonization
Q Zhu, DT Nguyen, E Sid, A Pariser
Methods of Information in Medicine 59 (04/05), 131-139, 2020
Mandates: US National Institutes of Health
Available somewhere: 42
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ...
Nature biotechnology 34 (8), 828-837, 2016
Mandates: US National Science Foundation, Swiss National Science Foundation, US …
The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
R Huang, N Southall, Y Wang, A Yasgar, P Shinn, A Jadhav, DT Nguyen, ...
Science translational medicine 3 (80), 80ps16-80ps16, 2011
Mandates: US National Institutes of Health
Unexplored therapeutic opportunities in the human genome
TI Oprea, CG Bologa, S Brunak, A Campbell, GN Gan, A Gaulton, ...
Nature reviews Drug discovery 17 (5), 317-332, 2018
Mandates: US National Institutes of Health, European Molecular Biology Laboratory …
Pharos: collating protein information to shed light on the druggable genome
DT Nguyen, S Mathias, C Bologa, S Brunak, N Fernandez, A Gaulton, ...
Nucleic acids research 45 (D1), D995-D1002, 2017
Mandates: US National Institutes of Health
The NCATS BioPlanet–an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics
R Huang, I Grishagin, Y Wang, T Zhao, J Greene, JC Obenauer, D Ngan, ...
Frontiers in pharmacology 10, 445, 2019
Mandates: US National Institutes of Health
Tox21Challenge to build predictive models of nuclear receptor and stress response pathways as mediated by exposure to environmental chemicals and drugs
R Huang, M Xia, DT Nguyen, T Zhao, S Sakamuru, J Zhao, SA Shahane, ...
Frontiers in Environmental Science 3, 85, 2016
Mandates: US National Institutes of Health
DrugCentral 2021 supports drug discovery and repositioning
S Avram, CG Bologa, J Holmes, G Bocci, TB Wilson, DT Nguyen, ...
Nucleic acids research 49 (D1), D1160-D1169, 2021
Mandates: US National Science Foundation, US National Institutes of Health
CoMPARA: collaborative modeling project for androgen receptor activity
K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ...
Environmental Health Perspectives 128 (2), 027002, 2020
Mandates: US Department of Energy, US National Institutes of Health, Federal Ministry …
Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3 …
J Jiang, K Ghoreschi, F Deflorian, Z Chen, M Perreira, M Pesu, J Smith, ...
Journal of medicinal chemistry 51 (24), 8012-8018, 2008
Mandates: US National Institutes of Health
High-frequency nano-optomechanical disk resonators in liquids
E Gil-Santos, C Baker, DT Nguyen, W Hease, C Gomez, A Lemaître, ...
Nature nanotechnology 10 (9), 810-816, 2015
Mandates: European Commission
A specific mechanism for nonspecific activation in reporter-gene assays
DS Auld, N Thorne, DT Nguyen, J Inglese
ACS chemical biology 3 (8), 463-470, 2008
Mandates: US National Institutes of Health
DrugCentral 2018: an update
O Ursu, J Holmes, CG Bologa, JJ Yang, SL Mathias, V Stathias, ...
Nucleic acids research 47 (D1), D963-D970, 2019
Mandates: US National Institutes of Health
TCRD and Pharos 2021: mining the human proteome for disease biology
TK Sheils, SL Mathias, KJ Kelleher, VB Siramshetty, DT Nguyen, ...
Nucleic Acids Research 49 (D1), D1334-D1346, 2021
Mandates: US National Institutes of Health
Photoelastic coupling in gallium arsenide optomechanical disk resonators
C Baker, W Hease, DT Nguyen, A Andronico, S Ducci, G Leo, I Favero
Optics express 22 (12), 14072-14086, 2014
Mandates: European Commission
CATMoS: collaborative acute toxicity modeling suite
K Mansouri, AL Karmaus, J Fitzpatrick, G Patlewicz, P Pradeep, D Alberga, ...
Environmental health perspectives 129 (4), 047013, 2021
Mandates: US Department of Energy, US National Institutes of Health
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk)
AS Rosenthal, C Tanega, M Shen, BT Mott, JM Bougie, DT Nguyen, ...
Bioorganic & medicinal chemistry letters 21 (10), 3152-3158, 2011
Mandates: US National Institutes of Health
Drug target ontology to classify and integrate drug discovery data
Y Lin, S Mehta, H Küçük-McGinty, JP Turner, D Vidovic, M Forlin, A Koleti, ...
Journal of biomedical semantics 8, 1-16, 2017
Mandates: US National Institutes of Health
Identification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening
SJ Shukla, DT Nguyen, R MacArthur, A Simeonov, WJ Frazee, TM Hallis, ...
Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA, 2010
Mandates: US National Institutes of Health
Novel consensus architecture to improve performance of large-scale multitask deep learning QSAR models
AV Zakharov, T Zhao, DT Nguyen, T Peryea, T Sheils, A Yasgar, R Huang, ...
Journal of chemical information and modeling 59 (11), 4613-4624, 2019
Mandates: US National Institutes of Health
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