Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment ME Rateb, WE Houssen, WTA Harrison, H Deng, CK Okoro, JA Asenjo, ... Journal of natural products 74 (9), 1965-1971, 2011 | 204 | 2011 |
Structural analysis of leader peptide binding enables leader-free cyanobactin processing J Koehnke, G Mann, AF Bent, H Ludewig, S Shirran, C Botting, T Lebl, ... Nature chemical biology 11 (8), 558-563, 2015 | 179 | 2015 |
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain J Koehnke, A Bent, WE Houssen, D Zollman, F Morawitz, S Shirran, ... Nature structural & molecular biology 19 (8), 767, 2012 | 154 | 2012 |
Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid Desert Streptomyces sp. ME Rateb, WE Houssen, M Arnold, MH Abdelrahman, H Deng, ... Journal of Natural products 74 (6), 1491-1499, 2011 | 153 | 2011 |
Induction of diverse secondary metabolites in Aspergillus fumigatus by microbial co-culture ME Rateb, I Hallyburton, WE Houssen, AT Bull, M Goodfellow, ... Rsc Advances 3 (34), 14444-14450, 2013 | 138 | 2013 |
The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction J Koehnke, AF Bent, D Zollman, K Smith, WE Houssen, X Zhu, G Mann, ... Angewandte Chemie International Edition 52 (52), 13991-13996, 2013 | 102 | 2013 |
Gracilins: Spongionella-derived promising compounds for Alzheimer disease M Leirós, E Alonso, ME Rateb, WE Houssen, R Ebel, M Jaspars, ... Neuropharmacology 93, 285-293, 2015 | 75 | 2015 |
An efficient method for the in vitro production of azol (in) e‐based cyclic peptides WE Houssen, AF Bent, AR McEwan, N Pieiller, J Tabudravu, J Koehnke, ... Angewandte Chemie International Edition 53 (51), 14171-14174, 2014 | 71 | 2014 |
Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors A Sallam, W Houssen, C Gissendanner, K Orabi, A Foudah, K El Sayed Med. Chem. Commun., 2013 | 70 | 2013 |
Bioactive Diterpene Derivatives from the Marine Sponge Spongionella sp. ME Rateb, WE Houssen, M Schumacher, WTA Harrison, M Diederich, ... Journal of natural products 72 (8), 1471-1476, 2009 | 69 | 2009 |
Azole-based cyclic peptides from the sea squirt Lissoclinum patella: old scaffolds, new avenues WE Houssen, M Jaspars ChemBioChem 11 (13), 1803-1815, 2010 | 63 | 2010 |
Isolation of marine natural products WE Houssen, M Jaspars Natural Products Isolation, 353-390, 2005 | 61* | 2005 |
The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation … MS Mady, MM Mohyeldin, HY Ebrahim, HE Elsayed, WE Houssen, ... Bioorganic & medicinal chemistry 24 (2), 113-122, 2016 | 56 | 2016 |
Butremycin, the 3-Hydroxyl Derivative of Ikarugamycin and a Protonated Aromatic Tautomer of 5′-Methylthioinosine from a Ghanaian Micromonospora sp. K310 K Kyeremeh, K Sekyi Acquah, A Sazak, W Houssen, J Tabudravu, ... Marine Drugs 12 (2), 999-1012, 2014 | 55 | 2014 |
Spongionella Secondary Metabolites Protect Mitochondrial Function in Cortical Neurons against Oxidative Stress M Leirós, JA Sánchez, E Alonso, ME Rateb, WE Houssen, R Ebel, ... Marine drugs 12 (2), 700-718, 2014 | 52 | 2014 |
A unique tryptophan C‐prenyltransferase from the Kawaguchipeptin biosynthetic pathway A Parajuli, DH Kwak, L Dalponte, N Leikoski, T Galica, U Umeobika, ... Angewandte Chemie International Edition 55 (11), 3596-3599, 2016 | 51 | 2016 |
Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons M Leiros, E Alonso, JA Sanchez, ME Rateb, R Ebel, WE Houssen, ... ACS Chemical Neuroscience 5 (1), 71-80, 2014 | 48 | 2014 |
The structural biology of patellamide biosynthesis J Koehnke, AF Bent, WE Houssen, G Mann, M Jaspars, JH Naismith Current opinion in structural biology 29, 112-121, 2014 | 46 | 2014 |
The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides WE Houssen, J Koehnke, D Zollman, J Vendome, A Raab, MCM Smith, ... ChemBioChem 13 (18), 2683-2689, 2012 | 46 | 2012 |
Isolation and anti-HIV-1 integrase activity of lentzeosides A–F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil D Wichner, H Idris, WE Houssen, AR McEwan, AT Bull, JA Asenjo, ... The Journal of antibiotics 70 (4), 448-453, 2017 | 45 | 2017 |