Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals M Guttman, I Amit, M Garber, C French, MF Lin, D Feldser, M Huarte, ... Nature 458 (7235), 223-227, 2009 | 4842 | 2009 |
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression AM Khalil, M Guttman, M Huarte, M Garber, A Raj, D Rivea Morales, ... Proceedings of the National Academy of Sciences 106 (28), 11667-11672, 2009 | 3337 | 2009 |
Gene regulation by long non-coding RNAs and its biological functions L Statello, CJ Guo, LL Chen, M Huarte Nature reviews Molecular cell biology 22 (2), 96-118, 2021 | 3304 | 2021 |
The emerging role of lncRNAs in cancer M Huarte Nature medicine 21 (11), 1253-1261, 2015 | 2578 | 2015 |
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response M Huarte, M Guttman, D Feldser, M Garber, MJ Koziol, ... Cell 142 (3), 409-419, 2010 | 2426 | 2010 |
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases JR Whetstine, A Nottke, F Lan, M Huarte, S Smolikov, Z Chen, E Spooner, ... Cell 125 (3), 467-481, 2006 | 1219 | 2006 |
LincRNA-p21 suppresses target mRNA translation JH Yoon, K Abdelmohsen, S Srikantan, X Yang, JL Martindale, S De, ... Molecular cell 47 (4), 648-655, 2012 | 1076 | 2012 |
The multidimensional mechanisms of long noncoding RNA function FP Marchese, I Raimondi, M Huarte Genome biology 18, 1-13, 2017 | 968 | 2017 |
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases S Iwase, F Lan, P Bayliss, L de la Torre-Ubieta, M Huarte, HH Qi, ... Cell 128 (6), 1077-1088, 2007 | 771 | 2007 |
Long non-coding RNAs: definitions, functions, challenges and recommendations JS Mattick, PP Amaral, P Carninci, S Carpenter, HY Chang, LL Chen, ... Nature reviews Molecular cell biology 24 (6), 430-447, 2023 | 669 | 2023 |
Large non-coding RNAs: missing links in cancer? M Huarte, JL Rinn Human molecular genetics 19 (R2), R152-R161, 2010 | 606 | 2010 |
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development HH Qi, M Sarkissian, GQ Hu, Z Wang, A Bhattacharjee, DB Gordon, ... Nature 466 (7305), 503-507, 2010 | 323 | 2010 |
PintlincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 O Marín-Béjar, FP Marchese, A Athie, Y Sánchez, J González, V Segura, ... Genome biology 14, 1-17, 2013 | 275 | 2013 |
Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature Y Sánchez, V Segura, O Marín-Béjar, A Athie, FP Marchese, J González, ... Nature communications 5 (1), 5812, 2014 | 212 | 2014 |
Long non-coding RNAs: challenges for diagnosis and therapies Y Sánchez, M Huarte Nucleic acid therapeutics 23 (1), 15-20, 2013 | 212 | 2013 |
Long non-coding RNAs and chromatin modifiers: their place in the epigenetic code FP Marchese, M Huarte Epigenetics 9 (1), 21-26, 2014 | 204 | 2014 |
Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression EB Affar, F Gay, Y Shi, H Liu, M Huarte, S Wu, T Collins, E Li, Y Shi Molecular and cellular biology, 2006 | 203 | 2006 |
The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element O Marín-Béjar, AM Mas, J González, D Martinez, A Athie, X Morales, ... Genome biology 18, 1-15, 2017 | 191 | 2017 |
PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators M Huarte, JJ Sanz-Ezquerro, F Roncal, J Ortı́n, A Nieto Journal of virology 75 (18), 8597-8604, 2001 | 167 | 2001 |
Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin F Li, M Huarte, M Zaratiegui, MW Vaughn, Y Shi, R Martienssen, ... Cell 135 (2), 272-283, 2008 | 150 | 2008 |