| Unique function of Kinesin Kif5A in localization of mitochondria in axons PD Campbell, K Shen, MR Sapio, TD Glenn, WS Talbot, FL Marlow Journal of Neuroscience 34 (44), 14717-14732, 2014 | 108 | 2014 |
| RNA-Seq investigations of human post-mortem trigeminal ganglia DM LaPaglia, MR Sapio, PD Burbelo, J Thierry-Mieg, D Thierry-Mieg, ... Cephalalgia 38 (5), 912-932, 2018 | 77 | 2018 |
| A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch CE Ramsden, AF Domenichiello, ZX Yuan, MR Sapio, GS Keyes, ... Science signaling 10 (493), eaal5241, 2017 | 73 | 2017 |
| Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist MJ Iadarola, MR Sapio, SJ Raithel, AJ Mannes, DC Brown Pain 159 (10), 2105-2114, 2018 | 70 | 2018 |
| Carboxypeptidases in disease: insights from peptidomic studies MR Sapio, LD Fricker PROTEOMICS–Clinical Applications 8 (5-6), 327-337, 2014 | 65 | 2014 |
| Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons MR Sapio, JK Neubert, DM LaPaglia, D Maric, JM Keller, SJ Raithel, ... The Journal of clinical investigation 128 (4), 1657-1670, 2018 | 64 | 2018 |
| Transcriptomic analyses of genes and tissues in inherited sensory neuropathies MR Sapio, SC Goswami, JR Gross, AJ Mannes, MJ Iadarola Experimental neurology 283, 375-395, 2016 | 59 | 2016 |
| Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss BE Hall, E Macdonald, M Cassidy, S Yun, MR Sapio, P Ray, M Doty, ... Scientific reports 12 (1), 4729, 2022 | 57 | 2022 |
| Carboxypeptidase A6 gene (CPA6) mutations in a recessive familial form of febrile seizures and temporal lobe epilepsy and in sporadic temporal lobe epilepsy A Salzmann, M Guipponi, PJ Lyons, LD Fricker, M Sapio, C Lambercy, ... Human mutation 33 (1), 124-135, 2012 | 56 | 2012 |
| Transcriptional changes in dorsal spinal cord persist after surgical incision despite preemptive analgesia with peripheral resiniferatoxin SJ Raithel, MR Sapio, DM LaPaglia, MJ Iadarola, AJ Mannes Anesthesiology 128 (3), 620-635, 2018 | 41 | 2018 |
| Dynorphin and enkephalin opioid peptides and transcripts in spinal cord and dorsal root ganglion during peripheral inflammatory hyperalgesia and allodynia MR Sapio, MJ Iadarola, AJ Loydpierson, JJ Kim, D Thierry-Mieg, ... The Journal of pain 21 (9-10), 988-1004, 2020 | 32 | 2020 |
| Zebrafish cytosolic carboxypeptidases 1 and 5 are essential for embryonic development PJ Lyons, MR Sapio, LD Fricker Journal of Biological Chemistry 288 (42), 30454-30462, 2013 | 30 | 2013 |
| Comparative analysis of dorsal root, nodose and sympathetic ganglia for the development of new analgesics MR Sapio, FA Vazquez, AJ Loydpierson, D Maric, JJ Kim, DM LaPaglia, ... Frontiers in Neuroscience 14, 615362, 2020 | 28 | 2020 |
| Transcriptomic segregation of human autoantigens useful for the diagnosis of autoimmune diseases PD Burbelo, MJ Iadarola, I Alevizos, MR Sapio Molecular diagnosis & therapy 20, 415-427, 2016 | 27 | 2016 |
| Phosphorylation of the transient receptor potential ankyrin 1 by cyclin-dependent kinase 5 affects chemo-nociception BE Hall, M Prochazkova, MR Sapio, P Minetos, N Kurochkina, ... Scientific Reports 8 (1), 1177, 2018 | 26 | 2018 |
| Haploinsufficiency of the brain-derived neurotrophic factor gene is associated with reduced pain sensitivity MR Sapio, MJ Iadarola, DM LaPaglia, T Lehky, AE Thurm, KM Danley, ... Pain 160 (5), 1070-1081, 2019 | 24 | 2019 |
| Novel carboxypeptidase A6 (CPA6) mutations identified in patients with juvenile myoclonic and generalized epilepsy MR Sapio, M Vessaz, P Thomas, P Genton, LD Fricker, A Salzmann PLoS One 10 (4), e0123180, 2015 | 24 | 2015 |
| Naturally occurring carboxypeptidase A6 mutations: effect on enzyme function and association with epilepsy MR Sapio, A Salzmann, M Vessaz, A Crespel, PJ Lyons, A Malafosse, ... Journal of Biological Chemistry 287 (51), 42900-42909, 2012 | 23 | 2012 |
| Analgesia by deletion of spinal neurokinin 1 receptor expressing neurons using a bioengineered substance P-Pseudomonas exotoxin conjugate MJ Iadarola, MR Sapio, X Wang, H Carrero, ML Virata-Theimer, ... Molecular pain 13, 1744806917727657, 2017 | 15 | 2017 |
| Pain treatment in the companion canine model to validate rodent results and incentivize the transition to human clinical trials MJ Iadarola, DC Brown, A Nahama, MR Sapio, AJ Mannes Frontiers in Pharmacology 12, 705743, 2021 | 13 | 2021 |
Michael J IadarolaDepartment of Perioperative Medicine, Clinical Center, NIHVerified email at nih.gov