BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ... Journal of Experimental Medicine 211 (4), 669-683, 2014 | 445 | 2014 |
High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries G Mullokandov, A Baccarini, A Ruzo, AD Jayaprakash, N Tung, ... Nature methods 9 (8), 840-846, 2012 | 427 | 2012 |
A balance between secreted inhibitors and edge sensing controls gastruloid self-organization F Etoc, J Metzger, A Ruzo, C Kirst, A Yoney, MZ Ozair, AH Brivanlou, ... Developmental cell 39 (3), 302-315, 2016 | 337 | 2016 |
Self-organization of a human organizer by combined Wnt and Nodal signalling I Martyn, TY Kanno, A Ruzo, ED Siggia, AH Brivanlou Nature 558 (7708), 132-135, 2018 | 290 | 2018 |
Whole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapy V Haurigot, S Marcó, A Ribera, M Garcia, A Ruzo, P Villacampa, E Ayuso, ... The Journal of clinical investigation 123 (8), 3254-3271, 2013 | 246 | 2013 |
A 3D model of a human epiblast reveals BMP4-driven symmetry breaking M Simunovic, JJ Metzger, F Etoc, A Yoney, A Ruzo, I Martyn, G Croft, ... Nature cell biology 21 (7), 900-910, 2019 | 167 | 2019 |
Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche P Baldominos, A Barbera-Mourelle, O Barreiro, Y Huang, A Wight, ... Cell 185 (10), 1694-1708. e19, 2022 | 154 | 2022 |
Self-organization of human embryonic stem cells on micropatterns A Deglincerti, F Etoc, MC Guerra, I Martyn, J Metzger, A Ruzo, ... Nature Protocols 11 (11), 2223-2232, 2016 | 154 | 2016 |
The miR-126–VEGFR2 axis controls the innate response to pathogen-associated nucleic acids J Agudo, A Ruzo, N Tung, H Salmon, M Leboeuf, D Hashimoto, C Becker, ... Nature immunology 15 (1), 54-62, 2014 | 153 | 2014 |
Correction of pathological accumulation of glycosaminoglycans in central nervous system and peripheral tissues of MPSIIIA mice through systemic AAV9 gene transfer A Ruzo, S Marcó, M García, P Villacampa, A Ribera, E Ayuso, L Maggioni, ... Human gene therapy 23 (12), 1237-1246, 2012 | 140 | 2012 |
Vascular endothelial growth factor–mediated islet hypervascularization and inflammation contribute to progressive reduction of β-cell mass J Agudo, E Ayuso, V Jimenez, A Casellas, C Mallol, A Salavert, S Tafuro, ... Diabetes 61 (11), 2851-2861, 2012 | 88 | 2012 |
Morphogen and community effects determine cell fates in response to BMP4 signaling in human embryonic stem cells A Nemashkalo, A Ruzo, I Heemskerk, A Warmflash Development 144 (17), 3042-3053, 2017 | 81 | 2017 |
WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ... Elife 7, e38279, 2018 | 77 | 2018 |
Phosphofructo-1-kinase deficiency leads to a severe cardiac and hematological disorder in addition to skeletal muscle glycogenosis M García, A Pujol, A Ruzo, E Riu, J Ruberte, A Arbós, A Serafín, B Albella, ... PLoS genetics 5 (8), e1000615, 2009 | 76 | 2009 |
hPSC modeling reveals that fate selection of cortical deep projection neurons occurs in the subplate MZ Ozair, C Kirst, BL van den Berg, A Ruzo, T Rito, AH Brivanlou Cell stem cell 23 (1), 60-73. e6, 2018 | 72 | 2018 |
Liver production of sulfamidase reverses peripheral and ameliorates CNS pathology in mucopolysaccharidosis IIIA mice A Ruzo, M Garcia, A Ribera, P Villacampa, V Haurigot, S Marcó, E Ayuso, ... Molecular Therapy 20 (2), 254-266, 2012 | 70 | 2012 |
Chromosomal instability during neurogenesis in Huntington's disease A Ruzo, GF Croft, JJ Metzger, S Galgoczi, LJ Gerber, C Pellegrini, ... Development 145 (2), dev156844, 2018 | 62 | 2018 |
GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions J Agudo, A Ruzo, ES Park, R Sweeney, V Kana, M Wu, Y Zhao, D Egli, ... Nature biotechnology 33 (12), 1287-1292, 2015 | 59 | 2015 |
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups ML Berres, KPH Lim, T Peters, J Price, H Takizawa, H Salmon, J Idoyaga, ... Journal of Experimental Medicine 212 (2), 281-281, 2015 | 51 | 2015 |
Nonviral-mediated hepatic expression of IGF-I increases Treg levels and suppresses autoimmune diabetes in mice XM Anguela, S Tafuro, C Roca, D Callejas, J Agudo, M Obach, A Ribera, ... Diabetes 62 (2), 551-560, 2013 | 49 | 2013 |