Articles with public access mandates - Melissa SpencerLearn more
Not available anywhere: 1
Myostatin inhibition promotes fast fibre hypertrophy but causes loss of AMP‐activated protein kinase signalling and poor exercise tolerance in a model of limb‐girdle muscular …
I Kramerova, M Marinov, J Owens, SJ Lee, D Becerra, MJ Spencer
The Journal of Physiology 598 (18), 3927-3939, 2020
Mandates: US National Institutes of Health
Available somewhere: 49
A single CRISPR-Cas9 deletion strategy that targets the majority of DMD patients restores dystrophin function in hiPSC-derived muscle cells
CS Young, MR Hicks, NV Ermolova, H Nakano, M Jan, S Younesi, ...
Cell stem cell 18 (4), 533-540, 2016
Mandates: US National Science Foundation, US National Institutes of Health
Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β
SA Vetrone, E Montecino-Rodriguez, E Kudryashova, I Kramerova, ...
The Journal of clinical investigation 119 (6), 1583-1594, 2009
Mandates: US National Institutes of Health
Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy
SA Villalta, W Rosenthal, L Martinez, A Kaur, T Sparwasser, JG Tidball, ...
Science translational medicine 6 (258), 258ra142-258ra142, 2014
Mandates: US National Institutes of Health
Calpain 3, the “gatekeeper” of proper sarcomere assembly, turnover and maintenance
JS Beckmann, M Spencer
Neuromuscular Disorders 18 (12), 913-921, 2008
Mandates: Swiss National Science Foundation, US National Institutes of Health
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs
MR Hicks, J Hiserodt, K Paras, W Fujiwara, A Eskin, M Jan, H Xi, ...
Nature cell biology 20 (1), 46-57, 2018
Mandates: US Department of Defense, US National Institutes of Health
Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H
E Kudryashova, I Kramerova, MJ Spencer
The Journal of clinical investigation 122 (5), 1764-1776, 2012
Mandates: US National Institutes of Health
Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component
E Kudryashova, J Wu, LA Havton, MJ Spencer
Human molecular genetics 18 (7), 1353-1367, 2009
Mandates: US National Institutes of Health
A human skeletal muscle atlas identifies the trajectories of stem and progenitor cells across development and from human pluripotent stem cells
H Xi, J Langerman, S Sabri, P Chien, CS Young, S Younesi, M Hicks, ...
Cell stem cell 27 (1), 158-176. e10, 2020
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, German …
Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype
J Capote, I Kramerova, L Martinez, S Vetrone, ER Barton, HL Sweeney, ...
Journal of Cell Biology 213 (2), 275-288, 2016
Mandates: US National Institutes of Health
Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle
I Kramerova, E Kudryashova, B Wu, C Ottenheijm, H Granzier, ...
Human molecular genetics 17 (21), 3271-3280, 2008
Mandates: US National Institutes of Health
Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy
GC Kendall, EI Mokhonova, M Moran, NE Sejbuk, DW Wang, O Silva, ...
Science translational medicine 4 (164), 164ra160-164ra160, 2012
Mandates: US National Institutes of Health
Creation of a novel humanized dystrophic mouse model of duchenne muscular dystrophy and application of a CRISPR/Cas9 gene editing therapy
CS Young, E Mokhonova, M Quinonez, AD Pyle, MJ Spencer
Journal of neuromuscular diseases 4 (2), 139-145, 2017
Mandates: US National Science Foundation, US National Institutes of Health
Emerging genetic therapies to treat Duchenne muscular dystrophy
SF Nelson, RH Crosbie, MC Miceli, MJ Spencer
Current opinion in neurology 22 (5), 532-538, 2009
Mandates: US National Institutes of Health
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization [S]
LC Chao, K Wroblewski, OR Ilkayeva, RD Stevens, J Bain, GA Meyer, ...
Journal of lipid research 53 (12), 2610-2619, 2012
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Calcium-dependent plasma membrane repair requires m-or μ-calpain, but not calpain-3, the proteasome, or caspases
RL Mellgren, K Miyake, I Kramerova, MJ Spencer, N Bourg, M Bartoli, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (12), 1886-1893, 2009
Mandates: US National Institutes of Health
Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle
I Kramerova, E Kudryashova, B Wu, S Germain, K Vandenborne, ...
Human molecular genetics 18 (17), 3194-3205, 2009
Mandates: US National Institutes of Health
Molecular and cellular basis of genetically inherited skeletal muscle disorders
JJ Dowling, CC Weihl, MJ Spencer
Nature Reviews Molecular Cell Biology 22 (11), 713-732, 2021
Mandates: US National Institutes of Health
Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice
MH Kim, DI Kay, RT Rudra, BM Chen, N Hsu, Y Izumiya, L Martinez, ...
Human molecular genetics 20 (7), 1324-1338, 2011
Mandates: US National Institutes of Health
Long-term administration of the TNF blocking drug Remicade (cV1q) to mdx mice reduces skeletal and cardiac muscle fibrosis, but negatively impacts cardiac function
NV Ermolova, L Martinez, SA Vetrone, MC Jordan, KP Roos, HL Sweeney, ...
Neuromuscular Disorders 24 (7), 583-595, 2014
Mandates: US National Institutes of Health
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