The ageing systemic milieu negatively regulates neurogenesis and cognitive function SA Villeda, J Luo, KI Mosher, B Zou, M Britschgi, G Bieri, TM Stan, ... Nature 477 (7362), 90-94, 2011 | 1901 | 2011 |
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ... Science translational medicine 6 (243), 243ra86-243ra86, 2014 | 784 | 2014 |
Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer’s disease KM Lucin, CE O’Brien, G Bieri, E Czirr, KI Mosher, RJ Abbey, ... Neuron 79 (5), 873-886, 2013 | 421 | 2013 |
The immunology of neurodegeneration E Czirr, T Wyss-Coray The Journal of clinical investigation 122 (4), 1156-1163, 2012 | 242 | 2012 |
Preclinical assessment of young blood plasma for Alzheimer disease J Middeldorp, B Lehallier, SA Villeda, SSM Miedema, E Evans, E Czirr, ... JAMA neurology 73 (11), 1325-1333, 2016 | 160 | 2016 |
Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity E Czirr, NA Castello, KI Mosher, JM Castellano, IV Hinkson, KM Lucin, ... Journal of Experimental Medicine 214 (4), 1081-1092, 2017 | 110 | 2017 |
Outer dense fibre protein 2 (ODF2) is a self-interacting centrosomal protein with affinity for microtubules FF Donkor, M Mönnich, E Czirr, T Hollemann, S Hoyer-Fender Journal of Cell Science 117 (20), 4643-4651, 2004 | 95 | 2004 |
Autoimmunity contributes to nociceptive sensitization in a mouse model of complex regional pain syndrome WW Li, TZ Guo, X Shi, E Czirr, T Stan, P Sahbaie, T Wyss-Coray, ... PAIN® 155 (11), 2377-2389, 2014 | 92 | 2014 |
Independent generation of Aβ42 and Aβ38 peptide species by γ-secretase E Czirr, BA Cottrell, S Leuchtenberger, T Kukar, TB Ladd, H Esselmann, ... Journal of Biological Chemistry 283 (25), 17049-17054, 2008 | 91 | 2008 |
α‐secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation S Jäger, S Leuchtenberger, A Martin, E Czirr, J Wesselowski, ... Journal of neurochemistry 111 (6), 1369-1382, 2009 | 78 | 2009 |
Insensitivity to Aβ42-lowering Nonsteroidal Anti-inflammatory Drugs and γ-Secretase Inhibitors Is Common among Aggressive Presenilin-1 Mutations*♦ E Czirr, S Leuchtenberger, C Dorner-Ciossek, A Schneider, M Jucker, ... Journal of Biological Chemistry 282 (34), 24504-24513, 2007 | 75 | 2007 |
Genetic variation in oocyte phenotype revealed through parthenogenesis and cloning: correlation with differences in pronuclear epigenetic modification S Gao, E Czirr, YG Chung, Z Han, KE Latham Biology of Reproduction 70 (4), 1162-1170, 2004 | 71 | 2004 |
Presenilin‐1 but not amyloid precursor protein mutations present in mouse models of Alzheimer’s disease attenuate the response of cultured cells to γ‐secretase modulators … S Hahn, T Brüning, J Ness, E Czirr, S Baches, H Gijsen, C Korth, ... Journal of neurochemistry 116 (3), 385-395, 2011 | 56 | 2011 |
Inhibitors of Rho‐kinase modulate amyloid‐β (Aβ) secretion but lack selectivity for Aβ42 S Leuchtenberger, MP Kummer, T Kukar, E Czirr, N Teusch, SA Sagi, ... Journal of neurochemistry 96 (2), 355-365, 2006 | 48 | 2006 |
γ-Secretase modulation with Aβ42-lowering nonsteroidal anti-inflammatory drugs and derived compounds E Czirr, S Weggen Neurodegenerative diseases 3 (4-5), 298-304, 2006 | 45 | 2006 |
Localisation of histone macroH2A1. 2 to the XY-body is not a response to the presence of asynapsed chromosome axes S Hoyer-Fender, E Czirr, R Radde, JMA Turner, SK Mahadevaiah, ... Journal of cell science 117 (2), 189-198, 2004 | 22 | 2004 |
Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products SP Braithwaite, E Czirr, I Gallager, N Huber, SS Minami US Patent 10,357,513, 2019 | 14 | 2019 |
Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein S Leuchtenberger, J Maler, E Czirr, J Ness, SF Lichtenthaler, ... Neurodegenerative diseases 6 (1-2), 1-8, 2008 | 13 | 2008 |
Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice R Britton, AT Liu, SV Rege, JM Adams, L Akrapongpisak, D Le, ... Brain and Behavior 12 (9), e2736, 2022 | 8 | 2022 |
Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products SP Braithwaite, MK Campbell, E Czirr, I Gallager, N Huber, S Jackson, ... US Patent 11,040,068, 2021 | 6 | 2021 |