Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule N Holler, R Zaru, O Micheau, M Thome, A Attinger, S Valitutti, JL Bodmer, ... Nature immunology 1 (6), 489-495, 2000 | 2253 | 2000 |
Serial triggering of many T-cell receptors by a few peptide–MHC complexes S Valitutti, S Müller, M Cella, E Padovan, A Lanzavecchia Nature 375 (6527), 148-151, 1995 | 1489 | 1995 |
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. S Valitutti, M Dessing, K Aktories, H Gallati, A Lanzavecchia The Journal of experimental medicine 181 (2), 577-584, 1995 | 661 | 1995 |
Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. S Valitutti, S Müller, M Dessing, A Lanzavecchia The Journal of experimental medicine 183 (4), 1917-1921, 1996 | 545 | 1996 |
CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation O Gaide, B Favier, DF Legler, D Bonnet, B Brissoni, S Valitutti, C Bron, ... Nature immunology 3 (9), 836-843, 2002 | 424 | 2002 |
Degradation of T cell receptor (TCR)–CD3-ζ complexes after antigenic stimulation S Valitutti, S Müller, M Salio, A Lanzavecchia The Journal of experimental medicine 185 (10), 1859-1864, 1997 | 414 | 1997 |
A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4+ T cells J Huang, M Brameshuber, X Zeng, J Xie, Q Li, Y Chien, S Valitutti, ... Immunity 39 (5), 846-857, 2013 | 413 | 2013 |
Migration of dendritic cells in response to formyl peptides, C5a, and a distinct set of chemokines. S Sozzani, F Sallusto, W Luini, D Zhou, L Piemonti, P Allavena, ... Journal of immunology (Baltimore, Md.: 1950) 155 (7), 3292-3295, 1995 | 408 | 1995 |
Different activation signals induce distinct mast cell degranulation strategies N Gaudenzio, R Sibilano, T Marichal, P Starkl, LL Reber, N Cenac, ... The Journal of clinical investigation 126 (10), 3981-3998, 2016 | 355 | 2016 |
Clonal deletion prunes but does not eliminate self-specific αβ CD8+ T lymphocytes W Yu, N Jiang, PJR Ebert, BA Kidd, S Müller, PJ Lund, J Juang, K Adachi, ... Immunity 42 (5), 929-941, 2015 | 346 | 2015 |
Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition S Valitutti, A Lanzavecchia Immunology today 18 (6), 299-304, 1997 | 330 | 1997 |
HLA-restricted, processing-and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes. MP Zanni, S von Greyerz, B Schnyder, KA Brander, K Frutig, Y Hari, ... The Journal of clinical investigation 102 (8), 1591-1598, 1998 | 281 | 1998 |
Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold M Faroudi, C Utzny, M Salio, V Cerundolo, M Guiraud, S Müller, S Valitutti Proceedings of the National Academy of Sciences 100 (24), 14145-14150, 2003 | 276 | 2003 |
Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses A Wiedemann, D Depoil, M Faroudi, S Valitutti Proceedings of the National Academy of Sciences 103 (29), 10985-10990, 2006 | 226 | 2006 |
Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes O Leupin, R Zaru, T Laroche, S Müller, S Valitutti Current Biology 10 (5), 277-280, 2000 | 205 | 2000 |
Immunological synapses are versatile structures enabling selective T cell polarization D Depoil, R Zaru, M Guiraud, A Chauveau, J Harriague, G Bismuth, ... Immunity 22 (2), 185-194, 2005 | 190 | 2005 |
Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion. E Padovan, C Giachino, M Cella, S Valitutti, O Acuto, A Lanzavecchia The Journal of experimental medicine 181 (4), 1587-1591, 1995 | 170 | 1995 |
Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling M Faroudi, R Zaru, P Paulet, S Müller, S Valitutti The Journal of Immunology 171 (3), 1128-1132, 2003 | 136 | 2003 |
Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells Š Bálint, S Müller, R Fischer, BM Kessler, M Harkiolaki, S Valitutti, ... Science 368 (6493), 897-901, 2020 | 131 | 2020 |
The diversity of immunological synapses A Trautmann, S Valitutti Current opinion in immunology 15 (3), 249-254, 2003 | 123 | 2003 |