| Continuous process for the separation of biologic components from heterogeneous cell populations WC Lake, R Giesler, D Van Epps, JR Chapman, JA Martinson, DR Ellis, ... US Patent 5,916,743, 1999 | 139 | 1999 |
| Apparatus for the separation of biologic components from heterogeneous cell populations R Giesler, JR Chapman, DR Ellis, DF Bischof US Patent 6,596,179, 2003 | 137 | 2003 |
| Continuous centrifugation process for the separation of biological components from heterogeneous cell populations WC Lake, R Giesler, D Van Epps, JR Chapman, JA Martinson, DR Ellis, ... US Patent 5,641,622, 1997 | 135 | 1997 |
| Apparatus and method for separating and isolating components of a biological fluid JR Chapman, V Kumar, BK Cinquini, PD Kingsley US Patent 8,177,072, 2012 | 128 | 2012 |
| Apparatus for separation of biologic components from heterogeneous cell populations R Giesler, JR Chapman, DR Ellis, DF Bischof US Patent 6,221,315, 2001 | 106 | 2001 |
| Method for inactivating pathogens in erythrocytes using photoactive compounds and plasma protein reduction J Chapman, PM Logan, HC Neyndorff, J North US Patent 5,360,734, 1994 | 87 | 1994 |
| Methods and apparatus for inactivating contaminants in biological fluid JR Chapman, PRH Stark, MV Swallow, DN Larson US Patent 6,190,609, 2001 | 81 | 2001 |
| Process for the preparation of pathogen‐inactivated RBC concentrates by using PEN110 chemistry: preclinical studies A Purmal, CR Valeri, W Dzik, L Pivacek, G Ragno, A Lazo, J Chapman Transfusion 42 (2), 139-145, 2002 | 69 | 2002 |
| Production of pathogen‐inactivated RBC concentrates using PEN110 chemistry: a Phase I clinical study JP AuBuchon, CA Pickard, LH Herschel, JC Roger, JE Tracy, A Purmal, ... Transfusion 42 (2), 146-152, 2002 | 62 | 2002 |
| Systems and methods for removing viral agents from blood RE Herman, J Chapman, CS Sun, JM Mathias, V Mayaudon, ... US Patent 6,190,855, 2001 | 62 | 2001 |
| Method of reducing the possibility of transmission of spongiform encephalopathy diseases by blood products J Chapman, J Fisher US Patent 6,197,207, 2001 | 61 | 2001 |
| Broad‐spectrum virus reduction in red cell concentrates using INACTINE™ PEN110 chemistry A Lazo, J Tassello, V Jayarama, A Ohagen, V Gibaja, E Kramer, ... Vox sanguinis 83 (4), 313-323, 2002 | 56 | 2002 |
| Method for purifying blood plasma and apparatus suitable therefor MA Sutter, NT Borton, DF Bischof, J Chapman, RE Herman, CS Sun US Patent 6,168,718, 2001 | 55 | 2001 |
| Changes in functional activities of plasma fibrinogen after treatment with methylene blue and red light AM Suontaka, M Blombäck, J Chapman Transfusion 43 (5), 568-575, 2003 | 54 | 2003 |
| Method and apparatus for inactivating contaminants in biological fluid JR Chapman, PRH Stark, MA Reed, DN Larson, DF Cuffaro US Patent 5,922,278, 1999 | 53 | 1999 |
| Whole blood thrombin: development of a process for intra-operative production of human thrombin V Kumar, JR Chapman The Journal of ExtraCorporeal Technology 39 (1), 18-23, 2007 | 52 | 2007 |
| Autologous thrombin: intraoperative production from whole blood V Kumar, JR Chapman The Journal of ExtraCorporeal Technology 40 (2), 94-98, 2008 | 48 | 2008 |
| West Nile virus in blood: stability, distribution, and susceptibility to PEN110 inactivation T Mather, T Takeda, J Tassello, A Ohagen, D Serebryanik, E Kramer, ... Transfusion 43 (8), 1029-1037, 2003 | 45 | 2003 |
| Inactivation of protozoan parasites in red blood cells using INACTINE PEN110 chemistry B Zavizion, M Pereira, M de Melo Jorge, D Serebryanik, TN Mather, ... Transfusion 44 (5), 731-738, 2004 | 43 | 2004 |
| Systems and methods for removing free and entrained contaminants in plasma CS Sun, J Chapman, DF Bischof, RE Herman US Patent 5,935,092, 1999 | 42 | 1999 |