Articles with public access mandates - Michael RiscoeLearn more
Not available anywhere: 1
Quinolone-3-diarylethers: a new class of antimalarial drug
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
Science translational medicine 5 (177), 177ra37-177ra37, 2013
Mandates: US National Institutes of Health
Available somewhere: 44
Chemical genetics of Plasmodium falciparum
WA Guiguemde, AA Shelat, D Bouck, S Duffy, GJ Crowther, PH Davis, ...
Nature 465 (7296), 311-315, 2010
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Discovery of dual function acridones as a new antimalarial chemotype
JX Kelly, MJ Smilkstein, R Brun, S Wittlin, RA Cooper, KD Lane, ...
Nature 459 (7244), 270-273, 2009
Mandates: US National Institutes of Health
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis
JS Doggett, A Nilsen, I Forquer, KW Wegmann, L Jones-Brando, ...
Proceedings of the National Academy of Sciences 109 (39), 15936-15941, 2012
Mandates: US National Institutes of Health
Antimalarial quinolones: synthesis, potency, and mechanistic studies
RW Winter, JX Kelly, MJ Smilkstein, R Dodean, D Hinrichs, MK Riscoe
Experimental parasitology 118 (4), 487-497, 2008
Mandates: US National Institutes of Health
Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers
A Nilsen, GP Miley, IP Forquer, MW Mather, K Katneni, Y Li, S Pou, ...
Journal of medicinal chemistry 57 (9), 3818-3834, 2014
Mandates: US National Institutes of Health
Optimization of endochin-like quinolones for antimalarial activity
R Winter, JX Kelly, MJ Smilkstein, D Hinrichs, DR Koop, MK Riscoe
Experimental parasitology 127 (2), 545-551, 2011
Mandates: US National Institutes of Health
Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes
JM Boitz, CA Gilroy, TD Olenyik, D Paradis, J Perdeh, K Dearman, ...
Infection and immunity 85 (1), 10.1128/iai. 00554-16, 2017
Mandates: US National Institutes of Health
Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone
LA Lawres, A Garg, V Kumar, I Bruzual, IP Forquer, I Renard, AZ Virji, ...
Journal of Experimental Medicine 213 (7), 1307-1318, 2016
Mandates: Bill & Melinda Gates Foundation, US National Institutes of Health, US …
ELQ-300 prodrugs for enhanced delivery and single-dose cure of malaria
GP Miley, S Pou, R Winter, A Nilsen, Y Li, JX Kelly, AM Stickles, ...
Antimicrobial agents and chemotherapy 59 (9), 5555-5560, 2015
Mandates: US National Institutes of Health, US Department of Veterans Affairs
Subtle Changes in Endochin-Like Quinolone Structure Alter the Site of Inhibition within the Cytochrome bc1 Complex of Plasmodium falciparum
AM Stickles, MJ De Almeida, JM Morrisey, KA Sheridan, IP Forquer, ...
Antimicrobial agents and chemotherapy 59 (4), 1977-1982, 2015
Mandates: US National Institutes of Health, US Department of Veterans Affairs
Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria
AM Stickles, MJ Smilkstein, JM Morrisey, Y Li, IP Forquer, JX Kelly, S Pou, ...
Antimicrobial agents and chemotherapy 60 (8), 4853-4859, 2016
Mandates: US National Institutes of Health, US Department of Veterans Affairs
Genetic Evidence for Cytochrome b Qi Site Inhibition by 4(1H)-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii
PH Alday, I Bruzual, A Nilsen, S Pou, R Winter, C Ben Mamoun, ...
Antimicrobial agents and chemotherapy 61 (2), 10.1128/aac. 01866-16, 2017
Mandates: US National Institutes of Health, US Department of Veterans Affairs
Inhibition of cytochrome bc1 as a strategy for single-dose, multi-stage antimalarial therapy
AM Stickles, LM Ting, JM Morrisey, Y Li, MW Mather, E Meermeier, ...
The American journal of tropical medicine and hygiene 92 (6), 1195, 2015
Mandates: US National Institutes of Health, US Department of Veterans Affairs
A drug-selected Plasmodium falciparum lacking the need for conventional electron transport
MJ Smilkstein, I Forquer, A Kanazawa, JX Kelly, RW Winter, DJ Hinrichs, ...
Molecular and biochemical parasitology 159 (1), 64-68, 2008
Mandates: US National Institutes of Health
Alkoxycarbonate ester prodrugs of preclinical drug candidate ELQ-300 for prophylaxis and treatment of malaria
L Frueh, Y Li, MW Mather, Q Li, S Pou, A Nilsen, RW Winter, IP Forquer, ...
ACS infectious diseases 3 (10), 728-735, 2017
Mandates: US Department of Defense, US National Institutes of Health, US Department of …
Targeting the Cytochrome bc1 Complex of Leishmania Parasites for Discovery of Novel Drugs
D Ortiz, I Forquer, J Boitz, R Soysa, C Elya, A Fulwiler, A Nilsen, T Polley, ...
Antimicrobial agents and chemotherapy 60 (8), 4972-4982, 2016
Mandates: US National Institutes of Health, US Department of Veterans Affairs
Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis
MH Foss, S Pou, PM Davidson, JL Dunaj, RW Winter, S Pou, MH Licon, ...
ACS infectious diseases 2 (7), 500-508, 2016
Mandates: US National Science Foundation, US National Institutes of Health, US …
Mefloquine and psychotomimetics share neurotransmitter receptor and transporter interactions in vitro
A Janowsky, AJ Eshleman, RA Johnson, KM Wolfrum, DJ Hinrichs, ...
Psychopharmacology 231, 2771-2783, 2014
Mandates: US National Institutes of Health
Sontochin as a guide to the development of drugs against chloroquine-resistant malaria
S Pou, RW Winter, A Nilsen, JX Kelly, Y Li, JS Doggett, EW Riscoe, ...
Antimicrobial agents and chemotherapy 56 (7), 3475-3480, 2012
Mandates: US National Institutes of Health
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