Sarcoma derived from cultured mesenchymal stem cells J Tolar, AJ Nauta, MJ Osborn, A Panoskaltsis Mortari, RT McElmurry, ... Stem cells 25 (2), 371-379, 2007 | 827 | 2007 |
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system SR Yant, L Meuse, W Chiu, Z Ivics, Z Izsvak, MA Kay Nature genetics 25 (1), 35-41, 2000 | 634 | 2000 |
Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo H Nakai, SR Yant, TA Storm, S Fuess, L Meuse, MA Kay Journal of virology 75 (15), 6969-6976, 2001 | 577 | 2001 |
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9 B Akache, D Grimm, K Pandey, SR Yant, H Xu, MA Kay Journal of virology 80 (19), 9831-9836, 2006 | 561 | 2006 |
High-resolution genome-wide mapping of transposon integration in mammals SR Yant, X Wu, Y Huang, B Garrison, SM Burgess, MA Kay Molecular and cellular biology, 2005 | 386 | 2005 |
Antiviral activity of bictegravir (GS-9883), a novel potent HIV-1 integrase strand transfer inhibitor with an improved resistance profile M Tsiang, GS Jones, J Goldsmith, A Mulato, D Hansen, E Kan, L Tsai, ... Antimicrobial agents and chemotherapy 60 (12), 7086-7097, 2016 | 291 | 2016 |
Clinical targeting of HIV capsid protein with a long-acting small molecule JO Link, MS Rhee, WC Tse, J Zheng, JR Somoza, W Rowe, R Begley, ... Nature 584 (7822), 614-618, 2020 | 271 | 2020 |
Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo SR Yant, A Ehrhardt, JG Mikkelsen, L Meuse, T Pham, MA Kay Nature biotechnology 20 (10), 999-1005, 2002 | 246 | 2002 |
Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver ZY Chen, SR Yant, CY He, L Meuse, S Shen, MA Kay Molecular Therapy 3 (3), 403-410, 2001 | 236 | 2001 |
Distinct pathways of genomic progression to benign and malignant tumors of the liver AD Tward, KD Jones, S Yant, ST Cheung, ST Fan, X Chen, MA Kay, ... Proceedings of the National Academy of Sciences 104 (37), 14771-14776, 2007 | 231 | 2007 |
Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid K Peng, W Muranyi, B Glass, V Laketa, SR Yant, L Tsai, T Cihlar, B Müller, ... Elife 3, e04114, 2014 | 198 | 2014 |
Helper-independent Sleeping Beauty transposon–transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo JG Mikkelsen, SR Yant, L Meuse, Z Huang, H Xu, MA Kay Molecular Therapy 8 (4), 654-665, 2003 | 188 | 2003 |
Mutational analysis of the N-terminal DNA-binding domain of sleeping beauty transposase: critical residues for DNA binding and hyperactivity in mammalian cells SR Yant, J Park, Y Huang, JG Mikkelsen, MA Kay Molecular and cellular biology 24 (20), 9239-9247, 2004 | 187 | 2004 |
High affinity YY1 binding motifs: identification of two core types (ACAT and CCAT) and distribution of potential binding sites within the human β globin cluster SR Yant, W Zhu, D Millinoff, JL Slightom, M Goodman, DL Gumucio Nucleic acids research 23 (21), 4353-4362, 1995 | 185 | 1995 |
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition E Montini, PK Held, M Noll, N Morcinek, M Al-Dhalimy, M Finegold, ... Molecular Therapy 6 (6), 759-769, 2002 | 175 | 2002 |
Site-directed transposon integration in human cells SR Yant, Y Huang, B Akache, MA Kay Nucleic acids research 35 (7), e50, 2007 | 165 | 2007 |
Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer S Ortiz-Urda, Q Lin, SR Yant, D Keene, MA Kay, PA Khavari Gene therapy 10 (13), 1099-1104, 2003 | 163 | 2003 |
Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells M Balakrishnan, SR Yant, L Tsai, C O’Sullivan, RA Bam, A Tsai, ... PloS one 8 (9), e74163, 2013 | 156 | 2013 |
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model SR Yant, A Mulato, D Hansen, WC Tse, A Niedziela-Majka, JR Zhang, ... Nature medicine 25 (9), 1377-1384, 2019 | 128 | 2019 |
Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OAT-dependent cytotoxicity RA Bam, SR Yant, T Cihlar Antiviral therapy 19 (7), 687-692, 2014 | 126 | 2014 |