Molecular cell biology HF Lodish Macmillan, 2008 | 13402 | 2008 |
Genome-scale CRISPR-mediated control of gene repression and activation LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ... Cell 159 (3), 647-661, 2014 | 2859 | 2014 |
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance JH Niess, S Brand, X Gu, L Landsman, S Jung, BA McCormick, JM Vyas, ... Science 307 (5707), 254-258, 2005 | 1961 | 2005 |
Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction EJHJ Wiertz, D Tortorella, M Bogyo, J Yu, W Mothes, TR Jones, ... Nature 384 (6608), 432-438, 1996 | 1439 | 1996 |
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol EJHJ Wiertz, TR Jones, L Sun, M Bogyo, HJ Geuze, HL Ploegh Cell 84 (5), 769-779, 1996 | 1386 | 1996 |
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining T Maruyama, SK Dougan, MC Truttmann, AM Bilate, JR Ingram, ... Nature biotechnology 33 (5), 538-542, 2015 | 1346 | 2015 |
Empty MHC class I molecules come out in the cold HG Ljunggren, NJ Stam, C Öhlén, JJ Neefjes, P Höglund, MT Heemels, ... Nature 346 (6283), 476-480, 1990 | 1150 | 1990 |
Herpes simplex virus turns off the TAP to evade host immunity A Hill, P Jugovic, lan York, G Russ, J Bennink, J Yewdell, H Ploegh, ... Nature 375 (6530), 411-415, 1995 | 1082 | 1995 |
Viral subversion of the immune system D Tortorella, BE Gewurz, MH Furman, DJ Schust, HL Ploegh Annual review of immunology 18 (1), 861-926, 2000 | 1028 | 2000 |
Viral strategies of immune evasion HL Ploegh Science 280 (5361), 248-253, 1998 | 1015 | 1998 |
The known unknowns of antigen processing and presentation JM Vyas, AG Van der Veen, HL Ploegh Nature Reviews Immunology 8 (8), 607-618, 2008 | 930 | 2008 |
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4− 8+ T cells L Van Kaer, PG Ashton-Rickardt, HL Ploegh, S Tonegawa Cell 71 (7), 1205-1214, 1992 | 877 | 1992 |
A membrane protein required for dislocation of misfolded proteins from the ER BN Lilley, HL Ploegh Nature 429 (6994), 834-840, 2004 | 862 | 2004 |
Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus T Nakagawa, W Roth, P Wong, A Nelson, A Farr, J Deussing, ... Science 280 (5362), 450-453, 1998 | 860 | 1998 |
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes YM Kim, MM Brinkmann, ME Paquet, HL Ploegh Nature 452 (7184), 234-238, 2008 | 842 | 2008 |
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments PJ Peters, JJ Neefjes, V Oorschot, HL Ploegh, HJ Geuze Nature 349 (6311), 669-676, 1991 | 824 | 1991 |
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration SM Lehmann, C Krüger, B Park, K Derkow, K Rosenberger, J Baumgart, ... Nature neuroscience 15 (6), 827-835, 2012 | 815 | 2012 |
Road to ruin: targeting proteins for degradation in the endoplasmic reticulum MH Smith, HL Ploegh, JS Weissman Science 334 (6059), 1086-1090, 2011 | 772 | 2011 |
Multiple associated proteins regulate proteasome structure and function DS Leggett, J Hanna, A Borodovsky, B Crosas, M Schmidt, RT Baker, ... Molecular cell 10 (3), 495-507, 2002 | 763 | 2002 |
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase RA Gruters, JJ Neefjes, M Tersmette, REY de Goede, A Tulp, ... Nature 330 (6143), 74-77, 1987 | 747 | 1987 |