| Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33 CA Christianson, NP Goplen, I Zafar, C Irvin, JT Good Jr, DR Rollins, ... Journal of Allergy and Clinical Immunology 136 (1), 59-68. e14, 2015 | 309 | 2015 |
| The role of low-level lactate production in airway inflammation in asthma M Ostroukhova, N Goplen, MZ Karim, L Michalec, L Guo, Q Liang, R Alam American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (3 …, 2012 | 145 | 2012 |
| MK2 controls the level of negative feedback in the NF-κB pathway and is essential for vascular permeability and airway inflammation MM Gorska, Q Liang, SJ Stafford, N Goplen, N Dharajiya, L Guo, S Sur, ... The Journal of experimental medicine 204 (7), 1637-1652, 2007 | 137 | 2007 |
| Immune signatures underlying post-acute COVID-19 lung sequelae IS Cheon, C Li, YM Son, NP Goplen, Y Wu, T Cassmann, Z Wang, X Wei, ... Science Immunology 6 (65), eabk1741, 2021 | 124 | 2021 |
| PD-1hi CD8+ resident memory T cells balance immunity and fibrotic sequelae Z Wang, S Wang, NP Goplen, C Li, IS Cheon, Q Dai, S Huang, J Shan, ... Science immunology 4 (36), eaaw1217, 2019 | 113 | 2019 |
| Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma N Goplen, MZ Karim, Q Liang, MM Gorska, S Rozario, L Guo, R Alam Journal of Allergy and Clinical Immunology 123 (4), 925-932. e11, 2009 | 109 | 2009 |
| PPAR-γ in macrophages limits pulmonary inflammation and promotes host recovery following respiratory viral infection S Huang, B Zhu, IS Cheon, NP Goplen, L Jiang, R Zhang, RS Peebles, ... Journal of virology 93 (9), 10.1128/jvi. 00030-19, 2019 | 107 | 2019 |
| Tissue-resident CD8+ T cells drive age-associated chronic lung sequelae after viral pneumonia NP Goplen, Y Wu, YM Son, C Li, Z Wang, IS Cheon, L Jiang, B Zhu, ... Science immunology 5 (53), eabc4557, 2020 | 103 | 2020 |
| Low-affinity T cells are programmed to maintain normal primary responses but are impaired in their recall to low-affinity ligands KM Knudson, NP Goplen, CA Cunningham, MA Daniels, E Teixeiro Cell reports 4 (3), 554-565, 2013 | 75 | 2013 |
| ERK1 is important for Th2 differentiation and development of experimental asthma N Goplen, Z Karim, L Guo, Y Zhuang, H Huang, MM Gorska, E Gelfand, ... The FASEB Journal, 2012 | 55 | 2012 |
| Senescent alveolar macrophages promote early-stage lung tumorigenesis LI Prieto, I Sturmlechner, SI Graves, C Zhang, NP Goplen, SY Eunhee, ... Cancer Cell 41 (7), 1261-1275. e6, 2023 | 48 | 2023 |
| Neonatal hyperoxia promotes asthma-like features through IL-33–dependent ILC2 responses IS Cheon, YM Son, L Jiang, NP Goplen, MH Kaplan, AH Limper, H Kita, ... Journal of Allergy and Clinical Immunology 142 (4), 1100-1112, 2018 | 44 | 2018 |
| Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection S Huang, NP Goplen, B Zhu, IS Cheon, Y Son, Z Wang, C Li, Q Dai, ... PLoS One 14 (10), e0223430, 2019 | 42 | 2019 |
| IL-12 signals through the TCR to support CD8 innate immune responses NP Goplen, V Saxena, KM Knudson, AG Schrum, D Gil, MA Daniels, ... The Journal of Immunology 197 (6), 2434-2443, 2016 | 38 | 2016 |
| Electron transport agents for organic electronic devices JG Bentsen, NP Goplen, Y Li, RR Roberts US Patent 7,271,406, 2007 | 35 | 2007 |
| Allergic airway recall responses require IL-9 from resident memory CD4+ T cells BJ Ulrich, R Kharwadkar, M Chu, A Pajulas, C Muralidharan, B Koh, Y Fu, ... Science immunology 7 (69), eabg9296, 2022 | 30 | 2022 |
| Aging and respiratory viral infection: from acute morbidity to chronic sequelae Y Wu, NP Goplen, J Sun Cell & Bioscience 11 (1), 112, 2021 | 30 | 2021 |
| Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function W Liu, K Tundwal, Q Liang, N Goplen, S Rozario, N Quayum, M Gorska, ... Molecular and cellular biology 30 (7), 1783-1799, 2010 | 30 | 2010 |
| Tissue-resident macrophages limit pulmonary CD8 resident memory T cell establishment NP Goplen, S Huang, B Zhu, IS Cheon, YM Son, Z Wang, C Li, Q Dai, ... Frontiers in immunology 10, 2332, 2019 | 29 | 2019 |
| Immune determinants of chronic sequelae after respiratory viral infection H Narasimhan, Y Wu, NP Goplen, J Sun Science Immunology 7 (73), eabm7996, 2022 | 24 | 2022 |
Jie SunHarrison Distinguished Teaching Professor of Medicine at the University of VirginiaVerified email at virginia.edu