The impact of oxidative DNA damage and stress on telomere homeostasis RP Barnes, E Fouquerel, PL Opresko Mechanisms of ageing and development 177, 37-45, 2019 | 443 | 2019 |
Targeted and persistent 8-oxoguanine base damage at telomeres promotes telomere loss and crisis E Fouquerel, RP Barnes, S Uttam, SC Watkins, MP Bruchez, PL Opresko Molecular cell 75 (1), 117-130. e6, 2019 | 223 | 2019 |
ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion E Fouquerel, EM Goellner, Z Yu, JP Gagne, MB de Moura, T Feinstein, ... Cell reports 8 (6), 1819-1831, 2014 | 223 | 2014 |
Oxidative guanine base damage regulates human telomerase activity E Fouquerel, J Lormand, A Bose, HT Lee, GS Kim, J Li, RW Sobol, ... Nature structural & molecular biology 23 (12), 1092-1100, 2016 | 172 | 2016 |
Radiation-induced mitotic catastrophe in PARG-deficient cells JC Amé, E Fouquerel, LR Gauthier, D Biard, FD Boussin, F Dantzer, ... Journal of cell science 122 (12), 1990-2002, 2009 | 156 | 2009 |
PARG is recruited to DNA damage sites through poly (ADP-ribose)-and PCNA-dependent mechanisms O Mortusewicz, E Fouquerel, JC Ame, H Leonhardt, V Schreiber Nucleic acids research 39 (12), 5045-5056, 2011 | 151 | 2011 |
Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction W Qian, N Kumar, V Roginskaya, E Fouquerel, PL Opresko, S Shiva, ... Proceedings of the National Academy of Sciences 116 (37), 18435-18444, 2019 | 129 | 2019 |
ARTD1 (PARP1) activation and NAD+ in DNA repair and cell death E Fouquerel, RW Sobol DNA repair 23, 27-32, 2014 | 122 | 2014 |
PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly (ADP-ribose) upon prolonged replicative stress G Illuzzi, E Fouquerel, JC Amé, A Noll, K Rehmet, HP Nasheuer, ... Nucleic acids research 42 (12), 7776-7792, 2014 | 80 | 2014 |
Damage sensor role of UV-DDB during base excision repair S Jang, N Kumar, EC Beckwitt, M Kong, E Fouquerel, V Rapić-Otrin, ... Nature structural & molecular biology 26 (8), 695-703, 2019 | 68 | 2019 |
DNA damage processing at telomeres: The ends justify the means E Fouquerel, D Parikh, P Opresko DNA repair 44, 159-168, 2016 | 41 | 2016 |
Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts D Parikh, E Fouquerel, CT Murphy, H Wang, PL Opresko Nature communications 6 (1), 8214, 2015 | 40 | 2015 |
PARP1 associates with R-loops to promote their resolution and genome stability N Laspata, P Kaur, SY Mersaoui, D Muoio, ZS Liu, MH Bannister, ... Nucleic acids research 51 (5), 2215-2237, 2023 | 31 | 2023 |
Synthesis and characterization of DNA minor groove binding alkylating agents P Iyer, A Srinivasan, SK Singh, GP Mascara, S Zayitova, B Sidone, ... Chemical research in toxicology 26 (1), 156-168, 2013 | 18 | 2013 |
Convergence of the nobel fields of telomere biology and DNA repair E Fouquerel, PL Opresko Photochemistry and photobiology 93 (1), 229-237, 2017 | 17 | 2017 |
Detection of the nuclear poly (ADP-ribose)-metabolizing enzymes and activities in response to DNA damage JC Amé, A Hakmé, D Quenet, E Fouquerel, F Dantzer, V Schreiber The Nucleus: Volume 2: Chromatin, Transcription, Envelope, Proteins …, 2008 | 16 | 2008 |
Functions of ADP-ribose transferases in the maintenance of telomere integrity D Muoio, N Laspata, E Fouquerel Cellular and Molecular Life Sciences 79 (4), 215, 2022 | 15 | 2022 |
γPNA FRET pair miniprobes for quantitative fluorescent in situ hybridization to telomeric DNA in cells and tissue A Orenstein, AS Berlyoung, EE Rastede, HH Pham, E Fouquerel, ... Molecules 22 (12), 2117, 2017 | 13 | 2017 |
Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins J Gao, QT Mewborne, A Girdhar, U Sheth, AN Coyne, R Punathil, ... Science translational medicine 14 (662), eabq3215, 2022 | 12 | 2022 |
Multifaceted role of PARP1 in maintaining genome stability through its binding to alternative DNA structures N Laspata, D Muoio, E Fouquerel Journal of Molecular Biology 436 (1), 168207, 2024 | 11 | 2024 |