CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 X Tai, M Cowan, L Feigenbaum, A Singer Nature immunology 6 (2), 152-162, 2005 | 845 | 2005 |
Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation D Klysz, X Tai, PA Robert, M Craveiro, G Cretenet, L Oburoglu, ... Science signaling 8 (396), ra97-ra97, 2015 | 479 | 2015 |
Response to RAG-mediated V (D) J cleavage by NBS1 and γ-H2AX HT Chen, A Bhandoola, MJ Difilippantonio, J Zhu, MJ Brown, X Tai, ... Science 290 (5498), 1962-1964, 2000 | 378 | 2000 |
Basis of CTLA-4 function in regulatory and conventional CD4+ T cells X Tai, F Van Laethem, L Pobezinsky, T Guinter, SO Sharrow, A Adams, ... Blood, The Journal of the American Society of Hematology 119 (22), 5155-5163, 2012 | 321 | 2012 |
Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals X Tai, B Erman, A Alag, J Mu, M Kimura, G Katz, T Guinter, T McCaughtry, ... Immunity 38 (6), 1116-1128, 2013 | 266 | 2013 |
Deletion of CD4 and CD8 coreceptors permits generation of αβT cells that recognize antigens independently of the MHC F Van Laethem, SD Sarafova, JH Park, X Tai, L Pobezinsky, TI Guinter, ... Immunity 27 (5), 735-750, 2007 | 230 | 2007 |
Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts Y Yashiro-Ohtani, XY Zhou, K Toyo-Oka, XG Tai, CS Park, T Hamaoka, ... the Journal of Immunology 164 (3), 1251-1259, 2000 | 220 | 2000 |
Clonal deletion and the fate of autoreactive thymocytes that survive negative selection LA Pobezinsky, GS Angelov, X Tai, S Jeurling, F Van Laethem, ... Nature immunology 13 (6), 569-578, 2012 | 198 | 2012 |
Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes J Mu, JP Zou, N Yamamoto, T Tsutsui, XG Tai, M Kobayashi, S Herrmann, ... Cancer research 55 (19), 4404-4408, 1995 | 172 | 1995 |
IL-7 signaling must be intermittent, not continuous, during CD8+ T cell homeostasis to promote cell survival instead of cell death MY Kimura, LA Pobezinsky, TI Guinter, J Thomas, A Adams, JH Park, ... Nature immunology 14 (2), 143-151, 2013 | 159 | 2013 |
Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4+ T cells: evidence from a lymphopenic T cell model A Bhandoola, X Tai, M Eckhaus, H Auchincloss, K Mason, SA Rubin, ... Immunity 17 (4), 425-436, 2002 | 132 | 2002 |
Molecular mechanisms underlying IFN-γ-mediated tumor growth inhibition induced during tumor growth inhibition induced during tumor immunotherapy with rIL-12 WG Yu, N Yamamoto, H Takenaka, J Mu, XG Tai, JP Zou, M Ogowa, ... International immunology 8 (6), 855-865, 1996 | 120 | 1996 |
Lck availability during thymic selection determines the recognition specificity of the T cell repertoire F Van Laethem, AN Tikhonova, LA Pobezinsky, X Tai, MY Kimura, ... Cell 154 (6), 1326-1341, 2013 | 117 | 2013 |
Induction of autoimmune disease in CTLA-4−/− mice depends on a specific CD28 motif that is required for in vivo costimulation X Tai, F Van Laethem, AH Sharpe, A Singer Proceedings of the National Academy of Sciences 104 (34), 13756-13761, 2007 | 112 | 2007 |
A role for CD9 molecules in T cell activation. XG Tai, Y Yashiro, R Abe, K Toyooka, CR Wood, J Morris, A Long, S Ono, ... The Journal of experimental medicine 184 (2), 753-758, 1996 | 108 | 1996 |
Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus TM McCaughtry, R Etzensperger, A Alag, X Tai, S Kurtulus, JH Park, ... Journal of Experimental Medicine 209 (12), 2263-2276, 2012 | 97 | 2012 |
A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co‐stimulatory molecules Y Yashiro, XG Tai, K Toyo‐oka, CS Park, R Abe, T Hamaoka, ... European journal of immunology 28 (3), 926-935, 1998 | 75 | 1998 |
Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes. XG Tai, K Toyo-oka, N Yamamoto, Y Yashiro, J Mu, T Hamaoka, ... Journal of immunology (Baltimore, Md.: 1950) 158 (10), 4696-4703, 1997 | 69 | 1997 |
Inhibition of growth and metastasis of ovarian carcinoma by administering a drug capable of interfering with vascular endothelial growth factor activity J Mu, Y Abe, T Tsutsui, N Yamamoto, XG Tai, O Niwa, T Tsujimura, B Sato, ... Japanese journal of cancer research 87 (9), 963-971, 1996 | 67 | 1996 |
CD9-mediated costimulation of TCR-triggered naive T cells leads to activation followed by apoptosis. XG Tai, K Toyooka, Y Yashiro, R Abe, CS Park, T Hamaoka, M Kobayashi, ... Journal of immunology (Baltimore, Md.: 1950) 159 (8), 3799-3807, 1997 | 66 | 1997 |