Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes N Rohani, L Hao, MS Alexis, BA Joughin, K Krismer, MN Moufarrej, ... Cancer research 79 (8), 1952-1966, 2019 | 205 | 2019 |
Network-based interpretation of diverse high-throughput datasets through the omics integrator software package N Tuncbag, SJC Gosline, A Kedaigle, AR Soltis, A Gitter, E Fraenkel PLoS computational biology 12 (4), e1004879, 2016 | 165 | 2016 |
Synergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca2+ handling AR Soltis, JJ Saucerman Biophysical journal 99 (7), 2038-2047, 2010 | 151 | 2010 |
Modeling cardiac β-adrenergic signaling with normalized-Hill differential equations: comparison with a biochemical model MJ Kraeutler, AR Soltis, JJ Saucerman BMC systems biology 4, 1-12, 2010 | 96 | 2010 |
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease S Bandres-Ciga, S Saez-Atienzar, JJ Kim, MB Makarious, F Faghri, ... Acta neuropathologica 140, 341-358, 2020 | 87 | 2020 |
Molecular analysis of clinically defined subsets of high-grade serous ovarian cancer S Lee, L Zhao, C Rojas, NW Bateman, H Yao, OD Lara, J Celestino, ... Cell reports 31 (2), 2020 | 80 | 2020 |
Hepatic dysfunction caused by consumption of a high-fat diet AR Soltis, NJ Kennedy, X Xin, F Zhou, SB Ficarro, YS Yap, BJ Matthews, ... Cell reports 21 (11), 3317-3328, 2017 | 77 | 2017 |
Pathogenic huntingtin repeat expansions in patients with frontotemporal dementia and amyotrophic lateral sclerosis R Dewan, R Chia, J Ding, RA Hickman, TD Stein, Y Abramzon, S Ahmed, ... Neuron 109 (3), 448-460. e4, 2021 | 73 | 2021 |
Association of variants in the SPTLC1 gene with juvenile amyotrophic lateral sclerosis JO Johnson, R Chia, DE Miller, R Li, R Kumaran, Y Abramzon, ... JAMA neurology 78 (10), 1236-1248, 2021 | 61 | 2021 |
The genetic architecture of Parkinson disease in Spain: characterizing population‐specific risk, differential haplotype structures, and providing etiologic insight S Bandres‐Ciga, S Ahmed, MS Sabir, C Blauwendraat, ... Movement Disorders 34 (12), 1851-1863, 2019 | 57 | 2019 |
Bmi1 promotes erythroid development through regulating ribosome biogenesis R Gao, S Chen, M Kobayashi, H Yu, Y Zhang, Y Wan, SK Young, A Soltis, ... Stem Cells 33 (3), 925-938, 2015 | 37 | 2015 |
Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington’s disease F Yildirim, CW Ng, V Kappes, T Ehrenberger, SK Rigby, V Stivanello, ... Proceedings of the National Academy of Sciences 116 (49), 24840-24851, 2019 | 35 | 2019 |
Proteogenomic analysis of lung adenocarcinoma reveals tumor heterogeneity, survival determinants, and therapeutically relevant pathways AR Soltis, NW Bateman, J Liu, T Nguyen, TJ Franks, X Zhang, CL Dalgard, ... Cell reports Medicine 3 (11), 2022 | 31 | 2022 |
Personalized single-cell proteogenomics to distinguish acute myeloid leukemia from nonmalignant clonal hematopoiesis LW Dillon, J Ghannam, C Nosiri, G Gui, M Goswami, KR Calvo, ... Blood cancer discovery 2 (4), 319-325, 2021 | 31 | 2021 |
Transcriptomic analysis of mouse brain after traumatic brain injury reveals that the angiotensin receptor blocker candesartan acts through novel pathways PJ Attilio, DM Snapper, M Rusnak, A Isaac, AR Soltis, MD Wilkerson, ... Frontiers in Neuroscience 15, 636259, 2021 | 17 | 2021 |
Transcriptomic profiling and pathway analysis of cultured human lung microvascular endothelial cells following ionizing radiation exposure RM Bouten, CL Dalgard, AR Soltis, JE Slaven, RM Day Scientific Reports 11 (1), 24214, 2021 | 16 | 2021 |
Survival motor neuron deficiency slows myoblast fusion through reduced myomaker and myomixer expression NM McCormack, E Villalón, C Viollet, AR Soltis, CL Dalgard, CL Lorson, ... Journal of cachexia, sarcopenia and muscle 12 (4), 1098-1116, 2021 | 16 | 2021 |
FOXP3 protects conventional human T cells from premature restimulation-induced cell death K Voss, C Lake, CR Luthers, NM Lott, B Dorjbal, S Arjunaraja, ... Cellular & Molecular Immunology 18 (1), 194-205, 2021 | 15 | 2021 |
Hyper-and hypo-nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis AR Soltis, S Motola, S Vernia, CW Ng, NJ Kennedy, S Dalin, BJ Matthews, ... Scientific reports 7 (1), 174, 2017 | 15 | 2017 |
Gene therapy-emulating small molecule treatments in cystic fibrosis airway epithelial cells and patients Q Yang, AR Soltis, G Sukumar, X Zhang, H Caohuy, J Freedy, CL Dalgard, ... Respiratory research 20, 1-15, 2019 | 14 | 2019 |