High-throughput mapping of the phage resistance landscape in E. coli VK Mutalik, BA Adler, HS Rishi, D Piya, C Zhong, B Koskella, EM Kutter, ... PLoS biology 18 (10), e3000877, 2020 | 125 | 2020 |
Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing BA Adler, T Hessler, BF Cress, A Lahiri, VK Mutalik, R Barrangou, ... Nature microbiology 7 (12), 1967-1979, 2022 | 57* | 2022 |
Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a GJ Knott, BF Cress, JJ Liu, BW Thornton, RJ Lew, B Al-Shayeb, ... Elife 8, e49110, 2019 | 48 | 2019 |
The genetic basis of phage susceptibility, cross-resistance and host-range in Salmonella BA Adler, AE Kazakov, C Zhong, H Liu, E Kutter, LM Lui, TN Nielsen, ... Microbiology 167 (12), 001126, 2021 | 45* | 2021 |
SCHEMA computational design of virus capsid chimeras: calibrating how genome packaging, protection, and transduction correlate with calculated structural disruption ML Ho, BA Adler, ML Torre, JJ Silberg, J Suh ACS synthetic biology 2 (12), 724-733, 2013 | 40 | 2013 |
Improved genome editing by an engineered CRISPR-Cas12a E Ma, K Chen, H Shi, EC Stahl, B Adler, M Trinidad, J Liu, K Zhou, J Ye, ... Nucleic Acids Research 50 (22), 12689-12701, 2022 | 38 | 2022 |
A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression CJ Huang, BA Adler, JA Doudna Molecular cell 82 (11), 2148-2160. e4, 2022 | 38 | 2022 |
A versatile platform strain for high-fidelity multiplex genome editing RG Egbert, HS Rishi, BA Adler, DM McCormick, E Toro, RT Gill, AP Arkin Nucleic acids research 47 (6), 3244-3256, 2019 | 19 | 2019 |
Sequential membrane-and protein-bound organelles compartmentalize genomes during phage infection EG Armbruster, J Lee, J Hutchings, AR VanderWal, E Enustun, BA Adler, ... bioRxiv, 2023 | 11 | 2023 |
Multicopy suppressor screens reveal convergent evolution of single-gene lysis proteins BA Adler, K Chamakura, H Carion, J Krog, AM Deutschbauer, R Young, ... Nature chemical biology 19 (6), 759-766, 2023 | 11* | 2023 |
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes BA Adler, MI Trinidad, D Bellieny-Rabelo, E Zhang, HM Karp, ... Nucleic acids research 52 (D1), D590-D596, 2024 | 8 | 2024 |
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes PH Yoon, P Skopintsev, H Shi, LX Chen, BA Adler, M Al-Shimary, ... Nucleic Acids Research 51 (22), 12414-12427, 2023 | 7 | 2023 |
A phage nucleus-associated RNA-binding protein is required for jumbo phage infection E Enustun, EG Armbruster, J Lee, S Zhang, BA Yee, K Malukhina, Y Gu, ... Nucleic Acids Research 52 (8), 4440-4455, 2024 | 6 | 2024 |
Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi BA Adler, MJ Al-Shimary, JR Patel, E Ambruster, D Colognori, EJ Charles, ... bioRxiv, 2023.09. 18.558157, 2023 | 5 | 2023 |
Hachiman is a genome integrity sensor OT Tuck, BA Adler, EG Armbruster, A Lahiri, JJ Hu, J Zhou, J Pogliano, ... bioRxiv, 2024 | 3 | 2024 |
To TnpB or not TnpB? Cas12 is the answer PH Yoon, BA Adler, JA Doudna Nature Chemical Biology 19 (3), 263-264, 2023 | 3 | 2023 |
An essential and highly selective protein import pathway encoded by nucleus-forming phage CJ Morgan, E Enustun, EG Armbruster, EA Birkholz, A Prichard, T Forman, ... Proceedings of the National Academy of Sciences 121 (19), e2321190121, 2024 | 2 | 2024 |
Toph (true retrieval of proteins homologs): Adapting a contrastive question-answering framework for protein search R Boger, A Lu, S Chithrananda, K Yang, P Skopintsev, B Adler, E Wallace, ... ICML workshop on computational biology, 2023 | 2 | 2023 |
Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases PH Yoon, Z Zhang, KJ Loi, BA Adler, A Lahiri, K Vohra, H Shi, DB Rabelo, ... Science 385 (6708), 538-543, 2024 | | 2024 |
Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis T Weiss, M Kamalu, H Shi, Z Li, J Amerasekera, Z Zhong, BA Adler, ... bioRxiv, 2024.07. 17.603964, 2024 | | 2024 |