Complete biosynthesis of cannabinoids and their unnatural analogues in yeast X Luo, MA Reiter, L d’Espaux, J Wong, CM Denby, A Lechner, Y Zhang, ... Nature 567 (7746), 123-126, 2019 | 643 | 2019 |
Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora N Ziemert, A Lechner, M Wietz, N Millán-Aguiñaga, KL Chavarria, ... Proceedings of the National Academy of Sciences 111 (12), E1130-E1139, 2014 | 317 | 2014 |
Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species KR Duncan, M Crüsemann, A Lechner, A Sarkar, J Li, N Ziemert, M Wang, ... Chemistry & biology 22 (4), 460-471, 2015 | 206 | 2015 |
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine AS Eustáquio, RP McGlinchey, Y Liu, C Hazzard, LL Beer, G Florova, ... Proceedings of the National Academy of Sciences 106 (30), 12295-12300, 2009 | 196 | 2009 |
Multi-omic data integration enables discovery of hidden biological regularities A Ebrahim, E Brunk, J Tan, EJ O'brien, D Kim, R Szubin, JA Lerman, ... Nature communications 7 (1), 13091, 2016 | 168 | 2016 |
The discovery of salinosporamide K from the marine bacterium “Salinispora pacifica” by genome mining gives insight into pathway evolution AS Eustáquio, SJ Nam, K Penn, A Lechner, MC Wilson, W Fenical, ... Chembiochem: a European journal of chemical biology 12 (1), 61, 2011 | 88 | 2011 |
Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A AJ Kale, RP McGlinchey, A Lechner, BS Moore ACS chemical biology 6 (11), 1257-1264, 2011 | 68 | 2011 |
The need for integrated approaches in metabolic engineering A Lechner, E Brunk, JD Keasling Cold Spring Harbor Perspectives in Biology 8 (11), a023903, 2016 | 51 | 2016 |
A streamlined ribosome profiling protocol for the characterization of microorganisms H Latif, R Szubin, J Tan, E Brunk, A Lechner, K Zengler, BO Palsson Biotechniques 58 (6), 329-332, 2015 | 48 | 2015 |
Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation A Lechner, AS Eustáquio, TAM Gulder, M Hafner, BS Moore Chemistry & biology 18 (12), 1527-1536, 2011 | 40 | 2011 |
Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering A Lechner, MC Wilson, YH Ban, J Hwang, YJ Yoon, BS Moore ACS Synthetic Biology, 2012 | 34 | 2012 |
Engineered Production of Short-Chain Acyl-Coenzyme A Esters in Saccharomyces cerevisiae N Krink-Koutsoubelis, AC Loechner, A Lechner, H Link, CM Denby, ... ACS Synthetic Biology 7 (4), 1105-1115, 2018 | 18 | 2018 |
Cultivation of the Paracalanid Copepod, Bestiolina similis (Calanoida: Crustacea) K VanderLugt, MJ Cooney, A Lechner, PH Lenz Journal of the World Aquaculture Society 40 (5), 616-628, 2009 | 17 | 2009 |
Expanding extender substrate selection for unnatural polyketide biosynthesis by acyltransferase domain exchange within a modular polyketide synthase E Englund, M Schmidt, AA Nava, A Lechner, K Deng, R Jocic, Y Lin, ... Journal of the American Chemical Society 145 (16), 8822-8832, 2023 | 15 | 2023 |
Recombinant microorganisms and methods for producing cannabinoids and cannabinoid derivatives JD Keasling, L D'espaux, J Wong, LUO Xiaozhou, M Reiter, C Denby, ... US Patent 10,563,211, 2020 | 12* | 2020 |
Predictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics GP Horsman, A Lechner, Y Ohnishi, BS Moore, B Shen Biochemistry 52 (31), 5217-5224, 2013 | 9 | 2013 |
Author Correction: Complete biosynthesis of cannabinoids and their unnatural analogues in yeast X Luo, MA Reiter, L d’Espaux, J Wong, CM Denby, A Lechner, Y Zhang, ... Nature 580 (7802), E2-E2, 2020 | 2 | 2020 |
Prenyltransferase variants and methods for production of prenylated aromatic compounds MA Noble, KG Hoff, A Lechner, H Nagarajan US Patent App. 18/316,993, 2023 | 1 | 2023 |
Prenyltransferase variants and methods for production of prenylated aromatic compounds MA Noble, KG Hoff, A Lechner, H Nagarajan US Patent 11,685,908, 2023 | 1 | 2023 |
Engineered cells for improved production of cannabinoids MA Noble, J Moore, J Li, A Lechner US Patent App. 17/427,019, 2022 | 1 | 2022 |