Chemically defined conditions for human iPSC derivation and culture G Chen, DR Gulbranson, Z Hou, JM Bolin, V Ruotti, MD Probasco, ... Nature methods 8 (5), 424-429, 2011 | 1691 | 2011 |
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis Z Hou, Y Zhang, NE Propson, SE Howden, LF Chu, EJ Sontheimer, ... Proceedings of the National Academy of Sciences 110 (39), 15644-15649, 2013 | 936 | 2013 |
Epigenomic analysis of multilineage differentiation of human embryonic stem cells W Xie, MD Schultz, R Lister, Z Hou, N Rajagopal, P Ray, JW Whitaker, ... Cell 153 (5), 1134-1148, 2013 | 788 | 2013 |
Complement C3aR inactivation attenuates tau pathology and reverses an immune network deregulated in tauopathy models and Alzheimer’s disease A Litvinchuk, YW Wan, DB Swartzlander, F Chen, A Cole, NE Propson, ... Neuron 100 (6), 1337-1353. e5, 2018 | 376 | 2018 |
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease ER Roy, B Wang, Y Wan, G Chiu, A Cole, Z Yin, NE Propson, Y Xu, ... The Journal of clinical investigation 130 (4), 1912-1930, 2020 | 357 | 2020 |
Human pluripotent stem cell-derived neural constructs for predicting neural toxicity MP Schwartz, Z Hou, NE Propson, J Zhang, CJ Engstrom, VS Costa, ... Proceedings of the National Academy of Sciences 112 (40), 12516-12521, 2015 | 350 | 2015 |
PSEN1ΔE9, APPswe, and APOE4 confer disparate phenotypes in human iPSC-derived microglia H Konttinen, S Ohtonen, S Wojciechowski, A Shakirzyanova, S Caligola, ... Stem cell reports 13 (4), 669-683, 2019 | 157 | 2019 |
Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging NE Propson, ER Roy, A Litvinchuk, J Köhl, H Zheng The Journal of clinical investigation 131 (1), 2021 | 147 | 2021 |
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease D Jennings, S Huntwork-Rodriguez, AG Henry, JC Sasaki, R Meisner, ... Science translational medicine 14 (648), eabj2658, 2022 | 134 | 2022 |
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models B van Lengerich, L Zhan, D Xia, D Chan, D Joy, JI Park, D Tatarakis, ... Nature neuroscience 26 (3), 416-429, 2023 | 104 | 2023 |
Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques ER Roy, G Chiu, S Li, NE Propson, R Kanchi, B Wang, C Coarfa, H Zheng, ... Immunity 55 (5), 879-894. e6, 2022 | 96 | 2022 |
Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading Y Xu, NE Propson, S Du, W Xiong, H Zheng Proceedings of the National Academy of Sciences 118 (27), e2023418118, 2021 | 94 | 2021 |
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease A Ghosh, MM Comerota, D Wan, F Chen, NE Propson, SH Hwang, ... Science translational medicine 12 (573), eabb1206, 2020 | 92 | 2020 |
Radially-oriented planar surfaces for flare reduction in panoramic cameras H Herman, S Singh, A Stentz, M Rondinelli US Patent 6,594,448, 2003 | 84* | 2003 |
MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers P Jiang, S Meyer, Z Hou, NE Propson, HT Soh, JA Thomson, R Stewart Bioinformatics 30 (18), 2665-2667, 2014 | 66 | 2014 |
Characterization and target identification of a DNA aptamer that labels pluripotent stem cells Z Hou, S Meyer, NE Propson, J Nie, P Jiang, R Stewart, JA Thomson Cell research 25 (3), 390-393, 2015 | 65 | 2015 |
Concurrent cell type–specific isolation and profiling of mouse brains in inflammation and Alzheimer’s disease DB Swartzlander, NE Propson, ER Roy, T Saito, T Saido, B Wang, ... JCI insight 3 (13), 2018 | 53 | 2018 |
Uniform neural tissue models produced on synthetic hydrogels using standard culture techniques C Barry, MT Schmitz, NE Propson, Z Hou, J Zhang, BK Nguyen, JM Bolin, ... Experimental Biology and Medicine 242 (17), 1679-1689, 2017 | 41 | 2017 |
Embryonic stem cell growth factors regulate eIF2α phosphorylation K Friend, HA Brooks, NE Propson, JA Thomson, J Kimble PloS one 10 (9), e0139076, 2015 | 36 | 2015 |
Complement in neurologic disease NE Propson, M Gedam, H Zheng Annual Review of Pathology: Mechanisms of Disease 16 (1), 277-298, 2021 | 32 | 2021 |