Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention EA Dennis, J Cao, YH Hsu, V Magrioti, G Kokotos Chemical reviews 111 (10), 6130-6185, 2011 | 1282 | 2011 |
Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function R Harkewicz, H Du, Z Tong, H Alkuraya, M Bedell, W Sun, X Wang, ... Journal of Biological Chemistry 287 (14), 11469-11480, 2012 | 109 | 2012 |
Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2 G Kokotos, YH Hsu, JE Burke, C Baskakis, CG Kokotos, V Magrioti, ... Journal of medicinal chemistry 53 (9), 3602-3610, 2010 | 107 | 2010 |
Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry YH Hsu, DS Dumlao, J Cao, EA Dennis PloS one 8 (3), e59267, 2013 | 80 | 2013 |
Localizing the membrane binding region of Group VIA Ca2+-independent phospholipase A2 using peptide amide hydrogen/deuterium exchange mass spectrometry YH Hsu, JE Burke, S Li, VL Woods, EA Dennis Journal of biological chemistry 284 (35), 23652-23661, 2009 | 78 | 2009 |
A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2 JE Burke, YH Hsu, RA Deems, S Li, VL Woods, EA Dennis Journal of biological chemistry 283 (45), 31227-31236, 2008 | 78 | 2008 |
Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses WH Chang, PY Liu, MH Lin, CJ Lu, HY Chou, CY Nian, YT Jiang, ... Molecules 26 (9), 2485, 2021 | 77 | 2021 |
Sorption of 2, 4-dichlorophenoxy propionic acid by organo-clay complexes YH Hsu, MK Wang, CW Pai, YS Wang Applied Clay Science 16 (3-4), 147-159, 2000 | 71 | 2000 |
Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry YH Hsu, JE Burke, DL Stephens, RA Deems, S Li, KM Asmus, VL Woods, ... Journal of biological chemistry 283 (15), 9820-9827, 2008 | 64 | 2008 |
Phosphatidylglycerol Incorporates into Cardiolipin to Improve Mitochondrial Activity and Inhibits Inflammation WW Chen, YJ Chao, WH Chang, JF Chan, YHH Hsu Scientific Reports 8 (1), 4919, 2018 | 58 | 2018 |
Fluoroketone inhibition of Ca2+-independent phospholipase A2 through binding pocket association defined by hydrogen/deuterium exchange and molecular dynamics YH Hsu, D Bucher, J Cao, S Li, SW Yang, G Kokotos, VL Woods Jr, ... Journal of the American Chemical Society 135 (4), 1330-1337, 2013 | 52 | 2013 |
Lipoprotein-associated phospholipase A2 interacts with phospholipid vesicles via a surface-disposed hydrophobic α-helix J Cao, YH Hsu, S Li, VL Woods Jr, EA Dennis Biochemistry 50 (23), 5314-5321, 2011 | 42 | 2011 |
Insertion of the Ca2+-independent phospholipase A2 into a phospholipid bilayer via coarse-grained and atomistic molecular dynamics simulations D Bucher, YH Hsu, VD Mouchlis, EA Dennis, JA McCammon PLoS computational biology 9 (7), e1003156, 2013 | 41 | 2013 |
Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange YH Hsu, DA Johnson, JA Traugh Journal of biological chemistry 283 (52), 36397-36405, 2008 | 35 | 2008 |
Double bonds of unsaturated fatty acids differentially regulate mitochondrial cardiolipin remodeling HC Ting, LT Chen, JY Chen, YL Huang, RC Xin, JF Chan, YHH Hsu Lipids in Health and Disease 18 (1), 53, 2019 | 26 | 2019 |
Structural basis of specific interactions of Lp-PLA2 with HDL revealed by hydrogen deuterium exchange mass spectrometry J Cao, YH Hsu, S Li, VL Woods, EA Dennis Journal of Lipid Research 54 (1), 127-133, 2013 | 26 | 2013 |
Polyunsaturated fatty acids incorporation into cardiolipin in H9c2 cardiac myoblast HC Ting, YJ Chao, YHH Hsu The Journal of nutritional biochemistry 26 (7), 769-775, 2015 | 25 | 2015 |
2-Oxoamide inhibitors of phospholipase A 2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides E Barbayianni, D Stephens, A Grkovich, V Magrioti, YH Hsu, P Dolatzas, ... Bioorganic & medicinal chemistry 17 (13), 4833-4843, 2009 | 25 | 2009 |
Omega-3 and omega-6 fatty acid differentially impact cardiolipin remodeling in activated macrophage WH Chang, HC Ting, WW Chen, JF Chan, YHH Hsu Lipids in Health and Disease 17 (1), 201, 2018 | 14 | 2018 |
Cardiolipin Interacts with Beta‐2‐Glycoprotein I and Forms an Open Conformation–Mechanisms Analyzed using Hydrogen/Deuterium Exchange KT Tang, TY Wu, HH Chen, CC Lin, YHH Hsu Protein Science, 2021 | 12 | 2021 |