Unraveling the mechanisms involved in motor neuron degeneration in ALS LI Bruijn, TM Miller, DW Cleveland Annu. Rev. Neurosci. 27 (1), 723-749, 2004 | 1687 | 2004 |
Distinct tau prion strains propagate in cells and mice and define different tauopathies DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ... Neuron 82 (6), 1271-1288, 2014 | 1033 | 2014 |
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ... Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013 | 889 | 2013 |
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia T Zu, Y Liu, M Bañez-Coronel, T Reid, O Pletnikova, J Lewis, TM Miller, ... Proceedings of the National Academy of Sciences 110 (51), E4968-E4977, 2013 | 872 | 2013 |
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration I Wegorzewska, S Bell, NJ Cairns, TM Miller, RH Baloh Proceedings of the National Academy of Sciences 106 (44), 18809-18814, 2009 | 823 | 2009 |
An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study TM Miller, A Pestronk, W David, J Rothstein, E Simpson, SH Appel, ... The Lancet Neurology 12 (5), 435-442, 2013 | 694 | 2013 |
Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria J Liu, C Lillo, PA Jonsson, CV Velde, CM Ward, TM Miller, ... Neuron 43 (1), 5-17, 2004 | 649 | 2004 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1267-1288, 2018 | 617 | 2018 |
C9orf72 is required for proper macrophage and microglial function in mice JG O’rourke, L Bogdanik, A Yáñez, D Lall, AJ Wolf, A Muhammad, R Ho, ... Science 351 (6279), 1324-1329, 2016 | 608 | 2016 |
Antisense oligonucleotide therapy for neurodegenerative disease RA Smith, TM Miller, K Yamanaka, BP Monia, TP Condon, G Hung, ... The Journal of clinical investigation 116 (8), 2290-2296, 2006 | 605 | 2006 |
Tau kinetics in neurons and the human central nervous system C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ... Neuron 97 (6), 1284-1298. e7, 2018 | 560 | 2018 |
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ... New England Journal of Medicine 383 (2), 109-119, 2020 | 485 | 2020 |
Trial of sodium phenylbutyrate–taurursodiol for amyotrophic lateral sclerosis S Paganoni, EA Macklin, S Hendrix, JD Berry, MA Elliott, S Maiser, ... New England Journal of Medicine 383 (10), 919-930, 2020 | 473 | 2020 |
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ... Science translational medicine 9 (374), eaag0481, 2017 | 459 | 2017 |
Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death TM Miller, KL Moulder, CM Knudson, DJ Creedon, M Deshmukh, ... The Journal of cell biology 139 (1), 205, 1997 | 458 | 1997 |
Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo SK Kaufman, DW Sanders, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, ... Neuron 92 (4), 796-812, 2016 | 426 | 2016 |
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS TM Miller, ME Cudkowicz, A Genge, PJ Shaw, G Sobue, RC Bucelli, ... New England Journal of Medicine 387 (12), 1099-1110, 2022 | 406 | 2022 |
Myopathy with antibodies to the signal recognition particle: clinical and pathological features T Miller, MT Al-Lozi, G Lopate, A Pestronk Journal of Neurology, Neurosurgery & Psychiatry 73 (4), 420-428, 2002 | 376 | 2002 |
Muscle cramps TM Miller, RB Layzer Muscle & Nerve: Official Journal of the American Association of …, 2005 | 352 | 2005 |
Antisense reduction of tau in adult mice protects against seizures SL DeVos, DK Goncharoff, G Chen, CS Kebodeaux, K Yamada, ... Journal of Neuroscience 33 (31), 12887-12897, 2013 | 350 | 2013 |