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Sepehr Dehghani-Ghahnaviyeh
Sepehr Dehghani-Ghahnaviyeh
Senior Scientist at Novartis Institutes for BioMedical Research
Verified email at novartis.com
Title
Cited by
Cited by
Year
Structures of the TMC-1 complex illuminate mechanosensory transduction
H Jeong, S Clark, A Goehring, S Dehghani-Ghahnaviyeh, A Rasouli, ...
Nature 610 (7933), 796-803, 2022
642022
Molecular mechanism of prestin electromotive signal amplification
J Ge, J Elferich, S Dehghani-Ghahnaviyeh, Z Zhao, M Meadows, ...
Cell 184 (18), 4669-4679. e13, 2021
642021
Complex self-propelled rings: a minimal model for cell motility
CA Velasco, SD Ghahnaviyeh, HN Pishkenari, T Auth, G Gompper
Soft Matter 13 (35), 5865-5876, 2017
312017
Membrane mixer: a toolkit for efficient shuffling of lipids in heterogeneous biological membranes
G Licari, S Dehghani-Ghahnaviyeh, E Tajkhorshid
Journal of chemical information and modeling 62 (4), 986-996, 2022
212022
Proton-driven alternating access in a spinster lipid transporter
R Dastvan, A Rasouli, S Dehghani-Ghahnaviyeh, S Gies, E Tajkhorshid
Nature communications 13 (1), 5161, 2022
182022
Conformational changes in the nucleotide‐binding domains of P‐glycoprotein induced by ATP hydrolysis
S Dehghani‐Ghahnaviyeh, K Kapoor, E Tajkhorshid
FEBS letters 595 (6), 735-749, 2021
172021
Differential dynamics and direct interaction of bound ligands with lipids in multidrug transporter ABCG2
A Rasouli, Q Yu, S Dehghani-Ghahnaviyeh, PC Wen, J Kowal, KP Locher, ...
Proceedings of the National Academy of Sciences 120 (1), e2213437120, 2023
152023
Modeling and simulation of three dimensional manipulations of biological micro/nanoparticles by applying cylindrical contact mechanics models by means of AFM
MH Korayem, MB Saraee, Z Mahmoodi, S Dehghani
Journal of Nanoparticle Research 17, 1-17, 2015
132015
Ionizable amino lipids distribution and effects on DSPC/cholesterol membranes: implications for lipid nanoparticle structure
S Dehghani-Ghahnaviyeh, M Smith, Y Xia, A Dousis, A Grossfield, S Sur
The Journal of Physical Chemistry B 127 (31), 6928-6939, 2023
92023
Lipid-mediated prestin organization in outer hair cell membranes and its implications in sound amplification
S Dehghani-Ghahnaviyeh, Z Zhao, E Tajkhorshid
Nature communications 13 (1), 6877, 2022
92022
Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms
LTM Le, JR Thompson, S Dehghani‐Ghahnaviyeh, S Pant, PX Dang, ...
The EMBO Journal 42 (3), e111065, 2023
82023
EFFECT OF DIFFERENT GEOMETRICAL PARAMETERS OF ATOMIC FORCE MICROSCOPE CANTILEVERS IN CRITICAL FORCE AND TIME BASED ON MANIPULATION BY APPLYING EFAST SENSITIVITY ANALYSES
KM HABIBNEJAD, GS DEHGHANI, M Ghasemi, M Taheri
Modares Mechanical Engineering 15 (1), 310-316, 2015
62015
Sobol method application in dimensional sensitivity analyses of different AFM cantilevers for biological particles
MH Korayem, M Taheri, SD Ghahnaviyeh
Modern Physics Letters B 29 (22), 1550123, 2015
42015
Backbone amides are determinants of Cl selectivity in CLC ion channels
L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, JD Galpin, ...
Nature communications 13 (1), 7508, 2022
32022
Martini 3 Force Field Parameters for Protein Lipidation Post-Translational Modifications
PI Koukos, S Dehghani-Ghahnaviyeh, C Velez-Vega, J Manchester, ...
Journal of Chemical Theory and Computation 19 (23), 8901-8918, 2023
22023
Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance
T Gose, A Rasouli, S Dehghani-Ghahnaviyeh, PC Wen, Y Wang, J Lynch, ...
Drug Resistance Updates 73, 101066, 2024
12024
Dissecting the Interaction Fingerprints and Binding Affinity of BYL719 Analogs Targeting PI3Kα
S Dehghani-Ghahnaviyeh, C Soylu, P Furet, C Velez-Vega
The Journal of Physical Chemistry B 128 (8), 1819-1829, 2024
2024
Interactions between ionizable amino lipids and a short RNA hairpin: Insights from molecular dynamics simulations for lipid nanoparticle optimization
AJ Poruthoor, S Dehghanighahnaviyeh, SK Bali, M Isik, S Sur
Biophysical Journal 123 (3), 97a, 2024
2024
Locked in place: Deciphering the conformational impairment caused by tumor-acquired somatic mutation Q393K in ABCG2
A Rasouli, T Gose, S Dehghani-Ghahnaviyeh, PC Wen, Y Wang, J Lynch, ...
Biophysical Journal 123 (3), 119a, 2024
2024
Proton-driven alternating access and broad-specificity in Spns lipid transporters
S Gies, K Jagessar, A Rasouli, S Dehghani-Ghahnaviyeh, I Miller, ...
Biophysical Journal 123 (3), 176a, 2024
2024
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