Clinical pharmacokinetics and pharmacodynamics of immune checkpoint inhibitors M Centanni, DJAR Moes, IF Trocóniz, J Ciccolini, JGC van Hasselt Clinical pharmacokinetics 58, 835-857, 2019 | 285 | 2019 |
Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-β kinase antagonist, in mice L Bueno, DP de Alwis, C Pitou, J Yingling, M Lahn, S Glatt, IF Trocóniz European journal of cancer 44 (1), 142-150, 2008 | 245 | 2008 |
Methadone: a review of its pharmacokinetic/pharmacodynamic properties MJ Garrido, IF Trocóniz Journal of pharmacological and toxicological methods 42 (2), 61-66, 1999 | 238 | 1999 |
A review of mixed‐effects models of tumor growth and effects of anticancer drug treatment used in population analysis B Ribba, NH Holford, P Magni, I Trocóniz, I Gueorguieva, P Girard, C Sarr, ... CPT: pharmacometrics & systems pharmacology 3 (5), 1-10, 2014 | 203 | 2014 |
Effects of the direct thrombin inhibitor dabigatran on ex vivo coagulation time in orthopaedic surgery patients: a population model analysis KH Liesenfeld, HG Schäfer, IF Trocóniz, C Tillmann, BI Eriksson, ... British journal of clinical pharmacology 62 (5), 527-537, 2006 | 150 | 2006 |
Population pharmacokinetic analysis of the new oral thrombin inhibitor dabigatran etexilate (BIBR 1048) in patients undergoing primary elective total hip replacement surgery IF Trocóniz, C Tillmann, KH Liesenfeld, HG Schäfer, J Stangier The Journal of Clinical Pharmacology 47 (3), 371-382, 2007 | 142 | 2007 |
Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effects of main active metabolites of tramadol,(+)-O-desmethyltramadol and (−)-O-desmethyltramadol, in rats M Valle, MJ Garrido, JM Pavón, R Calvo, IF Trocóniz Journal of Pharmacology and Experimental Therapeutics 293 (2), 646-653, 2000 | 117 | 2000 |
Optimizing oncology therapeutics through quantitative translational and clinical pharmacology: challenges and opportunities K Venkatakrishnan, LE Friberg, D Ouellet, JT Mettetal, A Stein, IF Trocóniz, ... Clinical Pharmacology & Therapeutics 97 (1), 37-54, 2015 | 100 | 2015 |
Intestinal absorption of penclomedine from lipid vehicles in the conscious rat: contribution of emulsification versus digestibility PC de Smidt, MA Campanero, IF Trocóniz International journal of pharmaceutics 270 (1-2), 109-118, 2004 | 94 | 2004 |
Modeling of the in vivo antinociceptive interaction between an opioid agonist,(+)-O-desmethyltramadol, and a monoamine reuptake inhibitor,(−)-O-desmethyltramadol, in rats MJ Garrido, M Valle, MA Campanero, R Calvo, IF Trocóniz Journal of Pharmacology and Experimental Therapeutics 295 (1), 352-359, 2000 | 93 | 2000 |
Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: application to pharmacokinetic … E Asín-Prieto, A Rodríguez-Gascón, IF Trocóniz, A Soraluce, J Maynar, ... Journal of Antimicrobial Chemotherapy 69 (1), 180-189, 2014 | 83 | 2014 |
Population pharmacokinetics of meropenem in critically ill patients undergoing continuous renal replacement therapy A Isla, A Rodríguez-Gascón, IF Trocóniz, L Bueno, MA Solinís, J Maynar, ... Clinical pharmacokinetics 47, 173-180, 2008 | 79 | 2008 |
Pharmacokinetic-pharmacodynamic modelling of the antipyretic effect of two oral formulations of ibuprofen IF Trocóniz, S Armenteros, MV Planelles, J Benítez, R Calvo, ... Clinical pharmacokinetics 38, 505-518, 2000 | 68 | 2000 |
Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity MJ Garrido, O Sayar, C Segura, J Rapado, MC Dios-Viéitez, MJ Renedo, ... Journal of Pharmacology and Experimental Therapeutics 305 (2), 710-718, 2003 | 67 | 2003 |
Application of different methods to formulate PEG-liposomes of oxaliplatin: evaluation in vitro and in vivo S Zalba, I Navarro, IF Trocóniz, CT de Ilarduya, MJ Garrido European journal of pharmaceutics and biopharmaceutics 81 (2), 273-280, 2012 | 62 | 2012 |
Modelling overdispersion and Markovian features in count data IF Trocóniz, EL Plan, R Miller, MO Karlsson Journal of pharmacokinetics and pharmacodynamics 36, 461-477, 2009 | 61 | 2009 |
Tramadol and O-Desmethyl Tramadol Clearance Maturation and Disposition in Humans: A Pooled Pharmacokinetic Study K Allegaert, N Holford, BJ Anderson, S Holford, F Stuber, A Rochette, ... Clinical pharmacokinetics 54, 167-178, 2015 | 58 | 2015 |
Modeling the effect of propofol and remifentanil combinations for sedation-analgesia in endoscopic procedures using an Adaptive Neuro Fuzzy Inference System (ANFIS) PL Gambús, EW Jensen, M Jospin, X Borrat, GM Pallí, ... Anesthesia & Analgesia 112 (2), 331-339, 2011 | 58 | 2011 |
Simultaneous determination of tramadol and its major active metabolite O-demethyltramadol by high-performance liquid chromatography with electrochemical detection M Valle, JM Pavon, R Calvo, MA Campanero, IF Troconiz Journal of Chromatography B: Biomedical Sciences and Applications 724 (1), 83-89, 1999 | 58 | 1999 |
Can pentylenetetrazole and maximal electroshock rodent seizure models quantitatively predict antiepileptic efficacy in humans? ESM Yuen, IF Trocóniz Seizure 24, 21-27, 2015 | 57 | 2015 |