| Synthesis, morphology, and properties of segmented poly (ether amide) s with uniform oxalamide-based hard segments NJ Sijbrandi, AJ Kimenai, EPC Mes, R Broos, G Bar, M Rosenthal, ... Macromolecules 45 (9), 3948-3961, 2012 | 63 | 2012 |
| A Novel Platinum (II)–Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F–Conjugated Trastuzumab NJ Sijbrandi, E Merkul, JA Muns, DCJ Waalboer, K Adamzek, M Bolijn, ... Cancer research 77 (2), 257-267, 2017 | 37 | 2017 |
| Synthesis, morphology and properties of segmented poly (ether ester amide) s comprising uniform glycine or β-alanine extended bisoxalamide hard segments NJ Sijbrandi, AJ Kimenai, EPC Mes, R Broos, G Bar, M Rosenthal, ... Polymer 53 (19), 4033-4044, 2012 | 30 | 2012 |
| Platinum (II) as Bifunctional Linker in Antibody–Drug Conjugate Formation: Coupling of a 4‐Nitrobenzo‐2‐oxa‐1, 3‐diazole Fluorophore to Trastuzumab as a Model DCJ Waalboer, JA Muns, NJ Sijbrandi, RBM Schasfoort, R Haselberg, ... ChemMedChem 10 (5), 797-803, 2015 | 27 | 2015 |
| Reversibly core-crosslinked PEG-P (HPMA) micelles: Platinum coordination chemistry for competitive-ligand-regulated drug delivery S Buwalda, B Nottelet, A Bethry, RJ Kok, N Sijbrandi, J Coudane Journal of colloid and interface science 535, 505-515, 2019 | 26 | 2019 |
| Folate-dactolisib conjugates for targeting tubular cells in polycystic kidneys H Shi, WN Leonhard, NJ Sijbrandi, MJ van Steenbergen, MHAM Fens, ... Journal of Controlled Release 293, 113-125, 2019 | 23 | 2019 |
| The antifibrotic potential of a sustained release formulation of a PDGFβ-receptor targeted rho kinase inhibitor F Van Dijk, N Teekamp, E Post, D Schuppan, YO Kim, J Zuidema, ... Journal of Controlled Release 296, 250-257, 2019 | 20 | 2019 |
| Structure formation and hydrogen bonding in all-aliphatic segmented copolymers with uniform hard segments YI Odarchenko, NJ Sijbrandi, M Rosenthal, AJ Kimenai, EPC Mes, ... Acta biomaterialia 9 (4), 6143-6149, 2013 | 20 | 2013 |
| In vivo characterization of platinum (II)-based linker technology for the development of antibody–drug conjugates: taking advantage of dual labeling with 195mPt and 89Zr JA Muns, V Montserrat, HJ Houthoff, K Codée-Van Der Schilden, ... Journal of Nuclear Medicine 59 (7), 1146-1151, 2018 | 19 | 2018 |
| First platinum (II)-based metal-organic linker technology (Lx®) for a plug-and-play development of antibody-drug conjugates (ADCs) E Merkul, NJ Sijbrandi, JA Muns, I Aydin, K Adamzek, HJ Houthoff, ... Expert Opinion on Drug Delivery 16 (8), 783-793, 2019 | 17 | 2019 |
| An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug Conjugates E Merkul, JA Muns, NJ Sijbrandi, HJ Houthoff, B Nijmeijer, ... Angewandte Chemie International Edition 60 (6), 3008-3015, 2021 | 15 | 2021 |
| Primary chemical sequence ultimately determines crystal thickness in segmented all-aliphatic copolymers YI Odarchenko, DV Anokhin, D Doblas, M Rosenthal, JJ Hernandez, ... Macromolecules 47 (22), 7890-7899, 2014 | 11 | 2014 |
| Method for preparing cell targeting conjugates, and the complexes obtained HJ Houthoff, AAMS Van Dongen, RJ Kok, DCJ Waalboer, SJ Buwalda, ... US Patent 10,668,162, 2020 | 8 | 2020 |
| A successful search for new, efficient, and silver-free manufacturing processes for key platinum (II) intermediates applied in antibody–drug conjugate (ADC) production E Merkul, NJ Sijbrandi, I Aydin, JA Muns, RJRW Peters, P Laarhoven, ... Green chemistry 22 (7), 2203-2212, 2020 | 5 | 2020 |
| Polymeric Micelles Employing Platinum (II) Linker for the Delivery of the Kinase Inhibitor Dactolisib H Shi, B Lou, MJ van Steenbergen, NJ Sijbrandi, WE Hennink, RJ Kok Particle & Particle Systems Characterization 36 (8), 1900236, 2019 | 3 | 2019 |
| Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-β JA Muns, E Schooten, RDJ van Dasselaar, YE Noordman, K Adamzek, ... European Journal of Nuclear Medicine and Molecular Imaging, 1-14, 2024 | 1 | 2024 |
| Internalizing binding molecules targeting receptors involved in cell proliferation or in cell differentiation HJ Houthoff, NJ Sijbrandi, JA Muns, JH Schooten, SD Pronk US Patent App. 17/436,629, 2022 | | 2022 |
| Methods for preparing cell targeting conjugates and conjugates obtainable by said methods E Merkul, NJ Sijbrandi, JA Muns, AAMS Van Dongen, PJGM Steverink, ... US Patent App. 16/956,467, 2021 | | 2021 |
| Cover Picture: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug … E Merkul, JA Muns, NJ Sijbrandi, HJ Houthoff, B Nijmeijer, ... Angewandte Chemie International Edition 60 (6), 2709-2709, 2021 | | 2021 |
| Titelbild: An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody–Drug … E Merkul, JA Muns, NJ Sijbrandi, HJ Houthoff, B Nijmeijer, G Rheenen, ... Angewandte Chemie 133 (6), 2021 | | 2021 |
