Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ... Nature genetics 47 (9), 979-986, 2015 | 2576 | 2015 |
Fine-mapping inflammatory bowel disease loci to single-variant resolution H Huang, M Fang, L Jostins, M Umićević Mirkov, G Boucher, ... Nature 547 (7662), 173-178, 2017 | 627 | 2017 |
Complex host genetics influence the microbiome in inflammatory bowel disease D Knights, MS Silverberg, RK Weersma, D Gevers, G Dijkstra, H Huang, ... Genome medicine 6, 1-11, 2014 | 438 | 2014 |
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 346 | 2015 |
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C Van Diemen, ... Nature communications 4 (1), 1342, 2013 | 200 | 2013 |
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease K Fransen, MC Visschedijk, S van Sommeren, JY Fu, L Franke, ... Human molecular genetics 19 (17), 3482-3488, 2010 | 127 | 2010 |
Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis LM Diaz-Gallo, L Espino-Paisán, K Fransen, M Gómez-García, ... Inflammatory bowel diseases 17 (11), 2287-2294, 2011 | 101 | 2011 |
Genome-wide association scan in north Indians reveals three novel HLA-independent risk loci for ulcerative colitis G Juyal, S Negi, A Sood, A Gupta, P Prasad, S Senapati, J Zaneveld, ... Gut 64 (4), 571-579, 2015 | 76 | 2015 |
Extraintestinal manifestations and complications in inflammatory bowel disease: from shared genetics to shared biological pathways S van Sommeren, M Janse, J Karjalainen, R Fehrmann, L Franke, J Fu, ... Inflammatory bowel diseases 20 (6), 987-994, 2014 | 61 | 2014 |
International IBD Genetics Consortium Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations JZ Liu, S van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ... Nat Genet 47 (9), 979-986, 2015 | 59 | 2015 |
HNF4α and CDH1 are associated with ulcerative colitis in a Dutch cohort S van Sommeren, MC Visschedijk, EAM Festen, DJ de Jong, ... Inflammatory bowel diseases 17 (8), 1714-1718, 2011 | 58 | 2011 |
Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer H Li, L Chan, P Bartuzi, SD Melton, A Weber, S Ben–Shlomo, C Varol, ... Gastroenterology 147 (1), 184-195. e3, 2014 | 44 | 2014 |
Correlation of genetic risk and messenger RNA expression in a Th17/IL23 pathway analysis in inflammatory bowel disease K Fransen, S van Sommeren, HJ Westra, M Veenstra, LE Lamberts, ... Inflammatory Bowel Diseases 20 (5), 777-782, 2014 | 29 | 2014 |
Association mapping of inflammatory bowel disease loci to single variant resolution H Huang, M Fang, L Jostins, MU Mirkov, G Boucher, CA Anderson, ... BioRxiv, 028688, 2015 | 26 | 2015 |
Genomic and expression analyses identify a disease-modifying variant for fibrostenotic Crohn’s disease MC Visschedijk, LM Spekhorst, SC Cheng, ES van Loo, BHD Jansen, ... Journal of Crohn's and Colitis 12 (5), 582-588, 2018 | 22 | 2018 |
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis M Akhlaghpour, T Haritunians, SK More, LS Thomas, DT Stamps, S Dube, ... Gut 72 (11), 2068-2080, 2023 | 8 | 2023 |
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. Nat Commun 4: 1342 SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C van Diemen, ... | 8 | 2013 |
HLA-DP on epithelial cells enables tissue damage by Nkp44+ natural killer cells in ulcerative colitis ME Baumdick, A Niehrs, F Degenhardt, M Schwerk, O Hinrichs, ... Gastroenterology 165 (4), 946-962. e13, 2023 | 5 | 2023 |
784 trans-ethnic association study of IBD identifies 14 new disease loci and demonstrates pervasive sharing of genetic risk factors and phenotypic features between Europeans … S Van Sommeren Gastroenterology 5 (146), S-133, 2014 | 3 | 2014 |
IDDF2019-ABS-0253 Explained variance and predictability of inflammatory bowel diseases by genetic risk score in five asian populations (results from the international IBD … S Abedian, SH Wong, S Van Sommeren, A Takahashi, JH Cheon, ... Gut 68 (Suppl 1), A110-A110, 2019 | 1 | 2019 |