Synergistic Inhibition by β2-Agonists and Corticosteroids on Tumor Necrosis Factor- α –Induced Interleukin-8 Release from Cultured Human Airway Smooth … L Pang, AJ Knox American Journal of Respiratory Cell and Molecular Biology 23 (1), 79-85, 2000 | 261 | 2000 |
Effect of interleukin‐1β, tumour necrosis factor‐α and interferon‐γ on the induction of cyclo‐oxygenase‐2 in cultured human airway smooth muscle cells L Pang, AJ Knox British journal of pharmacology 121 (3), 579-587, 1997 | 215 | 1997 |
Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis WR Coward, K Watts, CA Feghali-Bostwick, A Knox, L Pang Molecular and cellular biology 29 (15), 4325-4339, 2009 | 212 | 2009 |
TGF-β1 stimulates IL-8 release, COX-2 expression, and PGE2release in human airway smooth muscle cells CY Fong, L Pang, E Holland, AJ Knox American Journal of Physiology-Lung Cellular and Molecular Physiology 279 (1 …, 2000 | 185 | 2000 |
Regulation of TNF‐α‐induced eotaxin release from cultured human airway smooth muscle cells by β2‐agonists and corticosteroids L PANG, AJ KNOX The FASEB Journal 15 (1), 261-269, 2001 | 181 | 2001 |
TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB … DL Clarke, RL Clifford, S Jindarat, D Proud, L Pang, M Belvisi, AJ Knox Journal of Biological Chemistry 285 (38), 29101-29110, 2010 | 176 | 2010 |
Human airway smooth muscle cells secrete vascular endothelial growth factor: up‐regulation by bradykinin via a protein kinase C and prostanoid‐dependent mechanism AJ KNOX, L Corbett, J STOCKS, E HOLLAND, YM ZHU, L PANG The FASEB Journal 15 (13), 2480-2488, 2001 | 168 | 2001 |
Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma AL Tatler, AE John, L Jolly, A Habgood, J Porte, C Brightling, AJ Knox, ... The Journal of Immunology 187 (11), 6094-6107, 2011 | 153 | 2011 |
Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1β in human airway smooth muscle cells: involvement of different promoter elements, transcription … M Nie, L Pang, H Inoue, AJ Knox Molecular and cellular biology, 2003 | 142 | 2003 |
Bradykinin stimulates IL-8 production in cultured human airway smooth muscle cells: role of cyclooxygenase products L Pang, AJ Knox The Journal of Immunology 161 (5), 2509-2515, 1998 | 136 | 1998 |
PGE2 release by bradykinin in human airway smooth muscle cells: involvement of cyclooxygenase-2 induction L Pang, AJ Knox American Journal of Physiology-Lung Cellular and Molecular Physiology 273 (6 …, 1997 | 129 | 1997 |
Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis WR Coward, K Watts, CA Feghali-Bostwick, G Jenkins, L Pang Molecular and cellular biology, 2010 | 120 | 2010 |
Differential regulation of chemokine expression by peroxisome proliferator-activated receptor γ agonists: interactions with glucocorticoids and β2-agonists M Nie, L Corbett, AJ Knox, L Pang Journal of Biological Chemistry 280 (4), 2550-2561, 2005 | 119 | 2005 |
β2-Adrenoceptor agonists, like glucocorticoids, repress eotaxin gene transcription by selective inhibition of histone H4 acetylation M Nie, AJ Knox, L Pang The Journal of Immunology 175 (1), 478-486, 2005 | 118 | 2005 |
Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways JA Sánchez-Alcázar, DA Bradbury, L Pang, AJ Knox Lung Cancer 40 (1), 33-44, 2003 | 113 | 2003 |
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors L Pang, M Nie, L Corbett, AJ Knox The Journal of Immunology 170 (2), 1043-1051, 2003 | 111 | 2003 |
Repression of inducible nitric oxide synthase and cyclooxygenase-2 by prostaglandin E2 and other cyclic AMP stimulants in J774 macrophages L Pang, JRS Hoult Biochemical pharmacology 53 (4), 493-500, 1997 | 111 | 1997 |
A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis WR Coward, CA Feghali-Bostwick, G Jenkins, AJ Knox, L Pang The FASEB Journal 28 (7), 3183, 2014 | 110 | 2014 |
Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-κB p65, C/EBPβ, and RNA polymerase II binding to the CXCL8 promoter AE John, YM Zhu, CE Brightling, L Pang, AJ Knox The Journal of Immunology 183 (7), 4682-4692, 2009 | 99 | 2009 |
Inhibition of polyadenylation reduces inflammatory gene induction A Kondrashov, HA Meijer, A Barthet-Barateig, HN Parker, A Khurshid, ... Rna 18 (12), 2236-2250, 2012 | 93 | 2012 |