Unveiling the crucial intermediates in androgen production PJ Mak, MC Gregory, IG Denisov, SG Sligar, JR Kincaid Proceedings of the National Academy of Sciences 112 (52), 15856-15861, 2015 | 81 | 2015 |
Nanodiscs: a controlled bilayer surface for the study of membrane proteins MA McLean, MC Gregory, SG Sligar Annual review of biophysics 47 (1), 107-124, 2018 | 78 | 2018 |
Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry M Gregory, PJ Mak, SG Sligar, JR Kincaid Angewandte Chemie (International ed. in English) 52 (20), 5342, 2013 | 78 | 2013 |
Kinetic solvent isotope effect in human P450 CYP17A1-mediated androgen formation: evidence for a reactive peroxoanion intermediate MC Gregory, IG Denisov, YV Grinkova, Y Khatri, SG Sligar Journal of the American Chemical Society 135 (44), 16245-16247, 2013 | 77 | 2013 |
Active site proton delivery and the lyase activity of human CYP17A1 Y Khatri, MC Gregory, YV Grinkova, IG Denisov, SG Sligar Biochemical and biophysical research communications 443 (1), 179-184, 2014 | 68 | 2014 |
Nanodiscs in the studies of membrane-bound cytochrome P450 enzymes A Luthra, M Gregory, YV Grinkova, IG Denisov, SG Sligar Cytochrome P450 Protocols, 115-127, 2013 | 67 | 2013 |
Interaction of KRas4b with anionic membranes: A special role for PIP2 MC Gregory, MA McLean, SG Sligar Biochemical and biophysical research communications 487 (2), 351-355, 2017 | 53 | 2017 |
Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis R Duggal, Y Liu, MC Gregory, IG Denisov, JR Kincaid, SG Sligar Biochemical and biophysical research communications 477 (2), 202-208, 2016 | 43 | 2016 |
Human cytochrome CYP17A1: The structural basis for compromised lyase activity with 17-hydroxyprogesterone PJ Mak, R Duggal, IG Denisov, MC Gregory, SG Sligar, JR Kincaid Journal of the American Chemical Society 140 (23), 7324-7331, 2018 | 42 | 2018 |
Influence of transmembrane helix mutations on cytochrome P450-membrane interactions and function G Mustafa, PP Nandekar, TJ Camp, NJ Bruce, MC Gregory, SG Sligar, ... Biophysical journal 116 (3), 419-432, 2019 | 35 | 2019 |
Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17 PJ Mak, MC Gregory, SG Sligar, JR Kincaid Biochemistry 53 (1), 90-100, 2014 | 27 | 2014 |
Human P450 CYP17A1: Control of substrate preference by asparagine 202 MC Gregory, PJ Mak, Y Khatri, JR Kincaid, SG Sligar Biochemistry 57 (5), 764-771, 2018 | 10 | 2018 |
Importance of asparagine 202 in manipulating active site structure and substrate preference for human CYP17A1 Y Liu, I Denisov, M Gregory, SG Sligar, JR Kincaid Biochemistry 61 (7), 583-594, 2022 | 6 | 2022 |
Mechanism of the clinically relevant E305G mutation in human P450 CYP17A1 Y Liu, Y Grinkova, MC Gregory, IG Denisov, JR Kincaid, SG Sligar Biochemistry 60 (43), 3262-3271, 2021 | 6 | 2021 |
Understanding the mechanism of androgen biosynthesis MC Gregory University of Illinois at Urbana-Champaign, 2016 | 2 | 2016 |
Understanding the Role of Anionic Lipids in the Interaction of KRas4b with the Membrane Surface MA McLean, MC Gregory, T Camp, SG Sligar Biophysical Journal 116 (3), 298a, 2019 | | 2019 |
Mehanisms in Cancer Signaling: The Role of the Membrane in the Recruitment of the Oncogene KRas4b SG Sligar, MC Gregory, MA McLean Biophysical Journal 114 (3), 32a, 2018 | | 2018 |
Mechanism and Modulation of Human Androgen Synthesis R Duggal, MC Gregory, Y Liu, PJ Mak, IG Denisov, JR Kincaid, SG Sligar The FASEB Journal 31, 920.1-920.1, 2017 | | 2017 |
Anti-TGF beta receptor II antibody abrogates FoxP3+/TGF\# 946; RII+ Treg cells and enhances antitumor immunity against tumor growth and metastasis K Carroll, Z Zhong, D Policarpio, M Gregory, R Bassi, X Jimenez, ... CANCER RESEARCH 69, 2009 | | 2009 |
Abstract# 844: Anti-TGF beta receptor II antibody suppresses tumor growth and metastasis through inhibiting TGF beta autocrine stimulation of tumor cells and myeloid cells Z Zhong, D Policarpio, K Carroll, M Gregory, R Bassi, M Prewette, S Wang, ... Cancer Research 69 (9_Supplement), 844-844, 2009 | | 2009 |