Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease M Binks, JR Passweg, D Furst, P McSweeney, K Sullivan, C Besenthal, ... Annals of the rheumatic diseases 60 (6), 577-584, 2001 | 351 | 2001 |
Intrinsic dendritic cell abnormalities in Wiskott‐Aldrich syndrome M Binks, GE Jones, PM Brickell, C Kinnon, DR Katz, AJ Thrasher European journal of immunology 28 (10), 3259-3267, 1998 | 160 | 1998 |
Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis D Mewar, A Coote, DJ Moore, I Marinou, J Keyworth, MC Dickson, ... Arthritis research & therapy 8, 1-5, 2006 | 155 | 2006 |
Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor α, tumor necrosis factor receptor superfamily member … I Rioja, FJ Hughes, CH Sharp, LC Warnock, DS Montgomery, M Akil, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 146 | 2008 |
In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen H Drakesmith, D O’Neil, SC Schneider, M Binks, P Medd, E Sercarz, ... Proceedings of the National Academy of Sciences 95 (25), 14903-14908, 1998 | 122 | 1998 |
Association of interleukin‐6 and interleukin‐10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status I Marinou, J Healy, D Mewar, DJ Moore, MC Dickson, MH Binks, ... Arthritis & Rheumatism 56 (8), 2549-2556, 2007 | 107 | 2007 |
Innovative randomized phase I study and dosing regimen selection to accelerate and inform pivotal COVID‐19 trial of nirmatrelvir RSP Singh, SS Toussi, F Hackman, PL Chan, R Rao, R Allen, L Van Eyck, ... Clinical Pharmacology & Therapeutics 112 (1), 101-111, 2022 | 106 | 2022 |
Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non‐DRB1 loci C Vignal, AT Bansal, DJ Balding, MH Binks, MC Dickson, DS Montgomery, ... Arthritis & Rheumatism 60 (1), 53-62, 2009 | 93 | 2009 |
Human macrophage migration inhibitory factor: a proven immunomodulatory cytokine? A Kudrin, M Scott, S Martin, C Chung, R Donn, A McMaster, S Ellison, ... Journal of Biological Chemistry 281 (40), 29641-29651, 2006 | 84 | 2006 |
Investigation of selective JAK1 inhibitor GSK2586184 for the treatment of psoriasis in a randomized placebo‐controlled phase IIa study VJ Ludbrook, KJ Hicks, KE Hanrott, JS Patel, MH Binks, MR Wyres, ... British Journal of Dermatology 174 (5), 985-995, 2016 | 82 | 2016 |
Novel molecular mechanisms of dendritic cell-induced T cell activation VE Woodhead, TJ Stonehouse, MH Binks, K Speidel, DA Fox, A Gaya, ... International Immunology 12 (7), 1051-1061, 2000 | 67 | 2000 |
Categorizing natural history trajectories of ambulatory function measured by the 6-minute walk distance in patients with Duchenne muscular dystrophy E Mercuri, JE Signorovitch, E Swallow, J Song, SJ Ward, M Pane, ... Neuromuscular Disorders 26 (9), 576-583, 2016 | 65 | 2016 |
Safety, tolerability, efficacy and pharmacodynamics of the selective JAK1 inhibitor GSK2586184 in patients with systemic lupus erythematosus L Kahl, J Patel, M Layton, M Binks, K Hicks, G Leon, E Hachulla, ... Lupus 25 (13), 1420-1430, 2016 | 64 | 2016 |
Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry RS Coffin, SK Thomas, NSB Thomas, CE Lilley, AR Pizzey, CH Griffiths, ... Gene therapy 5 (5), 718-722, 1998 | 63 | 1998 |
From sentinel to messenger: an extended phenotypic analysis of the monocyte to dendritic cell transition WOODHEAD, BINKS, CHAIN, KATZ Immunology 94 (4), 552-559, 1998 | 60 | 1998 |
Pharmacokinetics of oral nirmatrelvir/ritonavir, a protease inhibitor for treatment of COVID‐19, in subjects with renal impairment SS Toussi, JM Neutel, J Navarro, RA Preston, H Shi, O Kavetska, ... Clinical Pharmacology & Therapeutics 112 (4), 892-900, 2022 | 57 | 2022 |
Association between radiographic severity of rheumatoid arthritis and shared epitope alleles: differing mechanisms of susceptibility and protection D Mewar, I Marinou, AL Coote, DJ Moore, M Akil, D Smillie, MC Dickson, ... Annals of the rheumatic diseases 67 (7), 980-983, 2008 | 57 | 2008 |
Safety, tolerability, pharmacokinetics, and pharmacodynamics of domagrozumab (PF‐06252616), an antimyostatin monoclonal antibody, in healthy subjects I Bhattacharya, S Pawlak, S Marraffino, J Christensen, SP Sherlock, ... Clinical pharmacology in drug development 7 (5), 484-497, 2018 | 54 | 2018 |
Randomized phase 2 trial and open-label extension of domagrozumab in Duchenne muscular dystrophy KR Wagner, HZ Abdel-Hamid, JK Mah, C Campbell, M Guglieri, F Muntoni, ... Neuromuscular Disorders 30 (6), 492-502, 2020 | 48 | 2020 |
Radiographic hand joint space width assessed by computer is a sensitive measure of change in early rheumatoid arthritis. J Angwin, A Lloyd, G Heald, G Nepom, M Binks, MF James The Journal of rheumatology 31 (6), 1050-1061, 2004 | 48 | 2004 |