Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion C Bonner, J Kerr-Conte, V Gmyr, G Queniat, E Moerman, J Thévenet, ... Nature medicine 21 (5), 512-517, 2015 | 713 | 2015 |
Human pancreatic β cell lncRNAs control cell-specific regulatory networks I Akerman, Z Tu, A Beucher, DMY Rolando, C Sauty-Colace, M Benazra, ... Cell metabolism 25 (2), 400-411, 2017 | 238 | 2017 |
AMP kinase–mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis CG Concannon, LP Tuffy, P Weisová, HP Bonner, D Dávila, C Bonner, ... Journal of Cell Biology 189 (1), 83-94, 2010 | 175 | 2010 |
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis PD Denechaud, IC Lopez-Mejia, A Giralt, Q Lai, E Blanchet, ... The Journal of clinical investigation 126 (1), 137-150, 2016 | 128 | 2016 |
Bile diversion in Roux-en-Y gastric bypass modulates sodium-dependent glucose intestinal uptake G Baud, M Daoudi, T Hubert, V Raverdy, M Pigeyre, E Hervieux, ... Cell metabolism 23 (3), 547-553, 2016 | 127 | 2016 |
Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway CG Concannon, BF Koehler, C Reimertz, BM Murphy, C Bonner, ... Oncogene 26 (12), 1681-1692, 2007 | 124 | 2007 |
Endoplasmic reticulum stress links oxidative stress to impaired pancreatic beta-cell function caused by human oxidized LDL V Plaisance, S Brajkovic, M Tenenbaum, D Favre, H Ezanno, ... PLoS One 11 (9), e0163046, 2016 | 109 | 2016 |
Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability … EM Jimenez-Mateos, S Hatazaki, MB Johnson, C Bellver-Estelles, ... Neurobiology of disease 32 (3), 442-453, 2008 | 87 | 2008 |
NMDA receptor‐mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner CG Concannon, MW Ward, HP Bonner, K Kuroki, LP Tuffy, CT Bonner, ... Journal of neurochemistry 105 (3), 891-903, 2008 | 56 | 2008 |
Microarray profile of seizure damage-refractory hippocampal CA3 in a mouse model of epileptic preconditioning S Hatazaki, C Bellver-Estelles, EM Jimenez-Mateos, R Meller, C Bonner, ... Neuroscience 150 (2), 467-477, 2007 | 55 | 2007 |
Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions M Imbernon, C Saponaro, HCC Helms, M Duquenne, D Fernandois, ... Cell metabolism 34 (7), 1054-1063. e7, 2022 | 53 | 2022 |
INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells C Bonner, S Bacon, CG Concannon, SR Rizvi, M Baquié, AM Farrelly, ... Diabetes 59 (11), 2799-2808, 2010 | 51 | 2010 |
AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF SM Kilbride, AM Farrelly, C Bonner, MW Ward, KC Nyhan, ... Journal of Biological Chemistry 285 (46), 36199-36206, 2010 | 50 | 2010 |
The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis D Kögel, CG Concannon, T Müller, H König, C Bonner, S Poeschel, ... Neurobiology of aging 33 (9), 2200-2209, 2012 | 48 | 2012 |
Interindividual heterogeneity of SGLT2 expression and function in human pancreatic islets C Saponaro, M Mühlemann, A Acosta-Montalvo, A Piron, V Gmyr, ... Diabetes 69 (5), 902-914, 2020 | 47 | 2020 |
Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY … S Bacon, MP Kyithar, J Schmid, SR Rizvi, C Bonner, R Graf, JHM Prehn, ... BMC endocrine disorders 12, 1-8, 2012 | 46 | 2012 |
SGLT2 inhibition and glucagon secretion in humans C Saponaro, F Pattou, C Bonner Diabetes & metabolism 44 (5), 383-385, 2018 | 42 | 2018 |
Exosome nanovesicles displaying G protein-coupled receptors for drug discovery A Estelles, J Sperinde, T Roulon, B Aguilar, C Bonner, JB LePecq, ... International journal of nanomedicine 2 (4), 751-760, 2007 | 41 | 2007 |
Sodium glucose transport modulation in type 2 diabetes and gastric bypass surgery G Baud, V Raverdy, C Bonner, M Daoudi, R Caiazzo, F Pattou Surgery for obesity and related diseases 12 (6), 1206-1212, 2016 | 38 | 2016 |
Identification of circulating microRNAs in HNF1A-MODY carriers C Bonner, KC Nyhan, S Bacon, MP Kyithar, J Schmid, CG Concannon, ... Diabetologia 56, 1743-1751, 2013 | 36 | 2013 |