Role of microRNAs in translation regulation and cancer S Oliveto, M Mancino, N Manfrini, S Biffo World journal of biological chemistry 8 (1), 45, 2017 | 443 | 2017 |
The translational machinery of human CD4+ T cells is poised for activation and controls the switch from quiescence to metabolic remodeling S Ricciardi, N Manfrini, R Alfieri, P Calamita, MC Crosti, S Gallo, R Müller, ... Cell metabolism 28 (6), 895-906. e5, 2018 | 156 | 2018 |
Mechanisms and regulation of DNA end resection MP Longhese, D Bonetti, N Manfrini, M Clerici The EMBO journal 29 (17), 2864-2874, 2010 | 154 | 2010 |
DNA double-strand breaks in meiosis: checking their formation, processing and repair MP Longhese, D Bonetti, I Guerini, N Manfrini, M Clerici DNA repair 8 (9), 1127-1138, 2009 | 123 | 2009 |
Regulation of the DNA damage response by cyclin-dependent kinases C Trovesi, N Manfrini, M Falcettoni, MP Longhese Journal of molecular biology 425 (23), 4756-4766, 2013 | 93 | 2013 |
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases N Manfrini, I Guerini, A Citterio, G Lucchini, MP Longhese Journal of Biological Chemistry 285 (15), 11628-11637, 2010 | 83 | 2010 |
The MRX complex plays multiple functions in resection of Yku-and Rif2-protected DNA ends D Bonetti, M Clerici, N Manfrini, G Lucchini, MP Longhese PloS one 5 (11), e14142, 2010 | 67 | 2010 |
RACK1 specifically regulates translation through its binding to ribosomes S Gallo, S Ricciardi, N Manfrini, E Pesce, S Oliveto, P Calamita, ... Molecular and cellular biology 38 (23), e00230-18, 2018 | 64 | 2018 |
Role of the Saccharomyces cerevisiae Rad53 Checkpoint Kinase in Signaling Double-Strand Breaks during the Meiotic Cell Cycle H Cartagena-Lirola, I Guerini, N Manfrini, G Lucchini, MP Longhese Molecular and cellular biology 28 (14), 4480-4493, 2008 | 57 | 2008 |
Exosomes recovered from the plasma of COVID-19 patients expose SARS-CoV-2 spike-derived fragments and contribute to the adaptive immune response E Pesce, N Manfrini, C Cordiglieri, S Santi, A Bandera, A Gobbini, ... Frontiers in Immunology 12, 785941, 2022 | 51 | 2022 |
Working hard at the nexus between cell signaling and the ribosomal machinery: an insight into the roles of RACK1 in translational regulation S Gallo, N Manfrini Translation 3 (2), e1120382, 2015 | 44 | 2015 |
Crosstalks between translation and metabolism in cancer S Biffo, N Manfrini, S Ricciardi Current opinion in genetics & development 48, 75-81, 2018 | 37 | 2018 |
RNA‐processing proteins regulate Mec1/ATR activation by promoting generation of RPA‐coated ss DNA N Manfrini, C Trovesi, M Wery, M Martina, D Cesena, M Descrimes, ... EMBO reports 16 (2), 221-231, 2015 | 37 | 2015 |
FAM46C and FNDC3A are multiple myeloma tumor suppressors that act in concert to impair clearing of protein aggregates and autophagy N Manfrini, M Mancino, A Miluzio, S Oliveto, M Balestra, P Calamita, ... Cancer Research 80 (21), 4693-4706, 2020 | 36 | 2020 |
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae N Manfrini, M Clerici, M Wery, CV Colombo, M Descrimes, A Morillon, ... Elife 4, e08942, 2015 | 31 | 2015 |
Translational control by mTOR-independent routes: how eIF6 organizes metabolism A Miluzio, S Ricciardi, N Manfrini, R Alfieri, S Oliveto, D Brina, S Biffo Biochemical Society Transactions 44 (6), 1667-1673, 2016 | 25 | 2016 |
Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma A Scagliola, A Miluzio, G Ventura, S Oliveto, C Cordiglieri, N Manfrini, ... Nature Communications 12 (1), 4878, 2021 | 23 | 2021 |
Ribosomal RACK1 promotes proliferation of neuroblastoma cells independently of global translation upregulation N Romano, M Veronese, N Manfrini, L Zolla, M Ceci Cellular signalling 53, 102-110, 2019 | 21 | 2019 |
High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice … N Manfrini, S Ricciardi, A Miluzio, M Fedeli, A Scagliola, S Gallo, D Brina, ... Developmental & Comparative Immunology 77, 69-76, 2017 | 20 | 2017 |
Discovery and preliminary characterization of translational modulators that impair the binding of eIF6 to 60S ribosomal subunits E Pesce, A Miluzio, L Turcano, C Minici, D Cirino, P Calamita, N Manfrini, ... Cells 9 (1), 172, 2020 | 16 | 2020 |