Mechanism of reversible self-association of a monoclonal antibody: role of electrostatic and hydrophobic interactions R Esfandiary, A Parupudi, J Casas-Finet, D Gadre, H Sathish Journal of pharmaceutical sciences 104 (2), 577-586, 2015 | 116 | 2015 |
A systematic multitechnique approach for detection and characterization of reversible self-association during formulation development of therapeutic antibodies R Esfandiary, DB Hayes, A Parupudi, J Casas-Finet, S Bai, HS Samra, ... Journal of pharmaceutical sciences 102 (9), 3089-3099, 2013 | 64 | 2013 |
Effects of salt-induced reversible self-association on the elution behavior of a monoclonal antibody in cation exchange chromatography H Luo, N Macapagal, K Newell, A Man, A Parupudi, Y Li, Y Li Journal of Chromatography A 1362, 186-193, 2014 | 57 | 2014 |
High-throughput self-interaction chromatography: applications in protein formulation prediction DH Johnson, A Parupudi, WW Wilson, LJ DeLucas Pharmaceutical research 26, 296-305, 2009 | 43 | 2009 |
Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions PS Sarangapani, J Weaver, A Parupudi, TMD Besong, GG Adams, ... Journal of pharmaceutical sciences 105 (12), 3496-3506, 2016 | 27 | 2016 |
Determination of interaction parameters for reversibly self-associating antibodies: a comparative analysis MM Hopkins, CL Lambert, JS Bee, A Parupudi, DL Bain Journal of Pharmaceutical Sciences 107 (7), 1820-1830, 2018 | 18 | 2018 |
Practical considerations for detection and characterization of sub-micron particles in protein solutions by nanoparticle tracking analysis F Gruia, A Parupudi, A Polozova PDA Journal of Pharmaceutical Science and Technology 69 (3), 427-439, 2015 | 16 | 2015 |
Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions SK Chaturvedi, A Parupudi, K Juul-Madsen, A Nguyen, T Vorup-Jensen, ... MAbs 12 (1), 1810488, 2020 | 15 | 2020 |
Electrostatically driven protein–protein interactions: Quantitative prediction of second osmotic virial coefficients to aid antibody design H Shahfar, Q Du, A Parupudi, L Shan, R Esfandiary, CJ Roberts The Journal of Physical Chemistry Letters 13 (5), 1366-1372, 2022 | 14 | 2022 |
Monoclonal antibody based in vitro potency assay as a predictor of antigenic integrity and in vivo immunogenicity of a Respiratory Syncytial Virus post-fusion F-protein based … MD Djagbare, L Yu, A Parupudi, J Sun, ML Coughlin, BS Rush, G Sanyal Vaccine 36 (12), 1673-1680, 2018 | 11 | 2018 |
Biophysical characterization of influenza A virions A Parupudi, F Gruia, SA Korman, S Dragulin-Otto, K Sra, RL Remmele Jr, ... Journal of Virological Methods 247, 91-98, 2017 | 9 | 2017 |
Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations A Parupudi, SK Chaturvedi, R Adão, RW Harkness, S Dragulin-Otto, ... Scientific Reports 11 (1), 5741, 2021 | 7 | 2021 |
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies A Dippel, A Gallegos, V Aleti, A Barnes, X Chen, E Christian, J Delmar, ... Mabs 15 (1), 2152526, 2023 | 6 | 2023 |
Deamidation in moxetumomab pasudotox leading to conformational change and immunotoxin activity loss X Lu, S Lin, N De Mel, A Parupudi, J Delmar, M Pandey, X Wang, J Wang Journal of Pharmaceutical Sciences 109 (9), 2676-2683, 2020 | 5 | 2020 |
Impact of mutations on the higher order structure and activity of a recombinant uricase F Gruia, A Parupudi, M Baca, C Ward, A Nyborg, RL Remmele Jr, JS Bee Journal of Pharmaceutical Sciences 106 (4), 1018-1024, 2017 | 4 | 2017 |
Energetic dissection of mab-specific reversible self-association reveals unique thermodynamic signatures MM Hopkins, A Parupudi, JS Bee, DL Bain Pharmaceutical Research 38, 243-255, 2021 | 3 | 2021 |
Comparative thermodynamics of the reversible self-association of therapeutic mAbs reveal opposing roles for linked proton-and ion-binding events MM Hopkins, IH Antonopoulos, A Parupudi, JS Bee, DL Bain Pharmaceutical Research 40 (6), 1383-1397, 2023 | 1 | 2023 |
Formulations of anti-il-33 antibodies S Ekizoglou, MSM Ahmed, R Esfandiary, A Parupudi US Patent App. 17/998,388, 2023 | | 2023 |
Formulation of Bispecific Antibodies A Parupudi WO Patent 2016036678A1, 2016 | | 2016 |