Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018 | 561 | 2018 |
Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo A Roghanian, I Teige, L Mårtensson, KL Cox, M Kovacek, A Ljungars, ... Cancer cell 27 (4), 473-488, 2015 | 150 | 2015 |
Advances in antibody phage display technology L Ledsgaard, A Ljungars, C Rimbault, CV Sørensen, T Tulika, J Wade, ... Drug Discovery Today 27 (8), 2151-2169, 2022 | 96 | 2022 |
A human ICAM-1 antibody isolated by a function-first approach has potent macrophage-dependent antimyeloma activity in vivo N Veitonmäki, M Hansson, F Zhan, A Sundberg, T Löfstedt, A Ljungars, ... Cancer cell 23 (4), 502-515, 2013 | 74 | 2013 |
Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes L Ledsgaard, J Wade, TP Jenkins, K Boddum, I Oganesyan, JA Harrison, ... Nature Communications 14 (1), 682, 2023 | 37 | 2023 |
LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation M Yeboah, C Papagregoriou, DC Jones, HTC Chan, G Hu, JS McPartlan, ... JCI insight 5 (18), 2020 | 37 | 2020 |
Deep mining of complex antibody phage pools generated by cell panning enables discovery of rare antibodies binding new targets and epitopes A Ljungars, C Svensson, A Carlsson, E Birgersson, UC Tornberg, ... Frontiers in Pharmacology 10, 847, 2019 | 33 | 2019 |
In vitro evolution of an antibody fragment population to find high-affinity hapten binders H Persson, H Wallmark, A Ljungars, J Hallborn, M Ohlin Protein Engineering, Design & Selection 21 (8), 485-493, 2008 | 33 | 2008 |
Assessing developability early in the discovery process for novel biologics ML Fernández-Quintero, A Ljungars, F Waibl, V Greiff, JT Andersen, ... MAbs 15 (1), 2171248, 2023 | 32 | 2023 |
High-throughput proteomics and in vitro functional characterization of the 26 medically most important elapids and vipers from sub-Saharan Africa GTT Nguyen, C O'Brien, Y Wouters, L Seneci, A Gallissà-Calzado, ... GigaScience 11, giac121, 2022 | 25 | 2022 |
A platform for phenotypic discovery of therapeutic antibodies and targets applied on Chronic Lymphocytic Leukemia A Ljungars, L Mårtensson, J Mattsson, M Kovacek, A Sundberg, ... NPJ precision oncology 2 (1), 18, 2018 | 21 | 2018 |
A neutralizing prolactin receptor antibody whose in vivo application mimics the phenotype of female prolactin receptor-deficient mice C Otto, A Särnefält, A Ljungars, S Wolf, B Rohde-Schulz, I Fuchs, ... Endocrinology 156 (11), 4365-4373, 2015 | 20 | 2015 |
A bispecific IgG format containing four independent antigen binding sites A Ljungars, T Schiött, U Mattson, J Steppa, B Hambe, M Semmrich, ... Scientific Reports 10 (1), 1546, 2020 | 13 | 2020 |
TRACERx Melanoma, TRACERx Renal, TRACERx Lung consortia, Pule M, Marafioti T, Gore M, Larkin J, Turajlic S, Swanton C, Peggs KS, Quezada SA. Fc Effector Function Contributes to … F Arce Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer Cell 33 (4), 649-663, 2018 | 13 | 2018 |
Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy CV Sørensen, L Ledsgaard, HHK Wildenauer, CH Dahl, TW Ebersole, ... Scientific Reports 13 (1), 10181, 2023 | 10 | 2023 |
Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies S Thumtecho, NJ Burlet, A Ljungars, AH Laustsen Journal of Venomous Animals and Toxins including Tropical Diseases 29, e20230057, 2023 | 9 | 2023 |
TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia, M FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Pule, T. Marafioti, M. Gore, J. Larkin, S. Turajlic, C. Swanton, KS Peggs …, 2018 | 9 | 2018 |
Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper CV Sørensen, J Fernández, AC Adams, HHK Wildenauer, S Schoffelen, ... Nature Communications 15 (1), 173, 2024 | 8 | 2024 |
De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments K Eloff, K Kalogeropoulos, O Morell, A Mabona, JB Jespersen, W Williams, ... bioRxiv, 2023.08. 30.555055, 2023 | 7 | 2023 |
Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies A Ljungars, AH Laustsen Toxicon 222, 106991, 2023 | 6 | 2023 |