Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange M Van Der Neut Kolfschoten, J Schuurman, M Losen, WK Bleeker, ... Science 317 (5844), 1554-1557, 2007 | 1141 | 2007 |
A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis P Zisimopoulou, P Evangelakou, J Tzartos, K Lazaridis, V Zouvelou, ... Journal of autoimmunity 52, 139-145, 2014 | 316 | 2014 |
MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4 MG Huijbers, W Zhang, R Klooster, EH Niks, MB Friese, KR Straasheijm, ... Proceedings of the National Academy of Sciences 110 (51), 20783-20788, 2013 | 289 | 2013 |
Effect of Oxygen Limitation and Medium Composition on Escherichia coli Fermentation in Shake‐Flask Cultures M Losen, B Frölich, M Pohl, J Büchs Biotechnology progress 20 (4), 1062-1068, 2004 | 238 | 2004 |
Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice R Klooster, JJ Plomp, MG Huijbers, EH Niks, KR Straasheijm, FJ Detmers, ... Brain 135 (4), 1081-1101, 2012 | 230 | 2012 |
The features of myasthenia gravis with autoantibodies to MuSK D Lavrnic, M Losen, A Vujic, M De Baets, LJ Hajdukovic, V Stojanovic, ... Journal of Neurology, Neurosurgery & Psychiatry 76 (8), 1099-1102, 2005 | 208 | 2005 |
The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria M Bosma, R Minnaard, LM Sparks, G Schaart, M Losen, MH De Baets, ... Histochemistry and cell biology 137, 205-216, 2012 | 193 | 2012 |
Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4 JJGM Verschuuren, MG Huijbers, JJ Plomp, EH Niks, PC Molenaar, ... Autoimmunity reviews 12 (9), 918-923, 2013 | 192 | 2013 |
Advances in understanding and modeling the gas–liquid mass transfer in shake flasks U Maier, M Losen, J Büchs Biochemical Engineering Journal 17 (3), 155-167, 2004 | 191 | 2004 |
Antibody effector mechanisms in myasthenia gravis—pathogenesis at the neuromuscular junction AM Gomez, J Van Den Broeck, K Vrolix, SP Janssen, MAM Lemmens, ... Autoimmunity 43 (5-6), 353-370, 2010 | 151 | 2010 |
Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis AM Gomez, K Vrolix, P Martínez-Martínez, PC Molenaar, M Phernambucq, ... The Journal of Immunology 186 (4), 2503-2513, 2011 | 143 | 2011 |
IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients I Koneczny, JAA Stevens, A De Rosa, S Huda, MG Huijbers, A Saxena, ... Journal of autoimmunity 77, 104-115, 2017 | 115 | 2017 |
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and … J Luo, P Taylor, M Losen, MH de Baets, GD Shelton, J Lindstrom Journal of Neuroscience 29 (44), 13898-13908, 2009 | 100 | 2009 |
Muscle disuse atrophy is not accompanied by changes in skeletal muscle satellite cell content T Snijders, BT Wall, ML Dirks, JMG Senden, F Hartgens, J Dolmans, ... Clinical science 126 (8), 557-566, 2014 | 94 | 2014 |
In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery J De Vry, P Martínez-Martínez, M Losen, Y Temel, T Steckler, ... Progress in neurobiology 92 (3), 227-244, 2010 | 89 | 2010 |
Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis M Losen, MHW Stassen, P Martínez-Martínez, BM Machiels, H Duimel, ... Brain 128 (10), 2327-2337, 2005 | 87 | 2005 |
MuSK autoantibodies in myasthenia gravis detected by cell based assay—a multinational study AI Tsonis, P Zisimopoulou, K Lazaridis, J Tzartos, E Matsigkou, ... Journal of neuroimmunology 284, 10-17, 2015 | 84 | 2015 |
IL‐17‐producing CD4+ T cells contribute to the loss of B‐cell tolerance in experimental autoimmune myasthenia gravis H Schaffert, A Pelz, A Saxena, M Losen, A Meisel, A Thiel, S Kohler European journal of immunology 45 (5), 1339-1347, 2015 | 79 | 2015 |
The auto-antigen repertoire in myasthenia gravis K Vrolix, J Fraussen, PC Molenaar, M Losen, V Somers, P Stinissen, ... Autoimmunity 43 (5-6), 380-400, 2010 | 76 | 2010 |
Titin antibodies in “seronegative” myasthenia gravis—a new role for an old antigen C Stergiou, K Lazaridis, V Zouvelou, J Tzartos, R Mantegazza, C Antozzi, ... Journal of neuroimmunology 292, 108-115, 2016 | 72 | 2016 |