High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis: mechanisms and a phase I/IIa study K Polireddy, R Dong, G Reed, J Yu, P Chen, S Williamson, PC Violet, ... Scientific reports 7 (1), 17188, 2017 | 146 | 2017 |
Exosomes as mediators of platinum resistance in ovarian cancer J Crow, S Atay, S Banskota, B Artale, S Schmitt, AK Godwin Oncotarget 8 (7), 11917, 2017 | 119 | 2017 |
Drug repurposing for gastrointestinal stromal tumor ZY Pessetto, SJ Weir, G Sethi, MA Broward, AK Godwin Molecular cancer therapeutics 12 (7), 1299-1309, 2013 | 115 | 2013 |
WJMSC‐derived small extracellular vesicle enhance T cell suppression through PD‐L1 M Li, R Soder, S Abhyankar, H Abdelhakim, MW Braun, CV Trinidad, ... Journal of extracellular vesicles 10 (4), e12067, 2021 | 54 | 2021 |
Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor ZY Pessetto, Y Ma, JJ Hirst, M von Mehren, SJ Weir, AK Godwin Molecular cancer therapeutics 13 (10), 2276-2287, 2014 | 50 | 2014 |
Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties J Hirst, HB Pathak, S Hyter, ZY Pessetto, T Ly, S Graw, DC Koestler, ... Cancer research 78 (15), 4370-4385, 2018 | 48 | 2018 |
Inhibition of BRCT (BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal … ZY Pessetto, Y Yan, T Bessho, A Natarajan Breast cancer research and treatment 134, 511-517, 2012 | 47 | 2012 |
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma ZY Pessetto, B Chen, H Alturkmani, S Hyter, CA Flynn, M Baltezor, Y Ma, ... Oncotarget 8 (3), 4079, 2017 | 43 | 2017 |
Role of miR-139 as a surrogate marker for tumor aggression in breast cancer H Dai, D Gallagher, S Schmitt, ZY Pessetto, F Fan, AK Godwin, O Tawfik Human pathology 61, 68-77, 2017 | 32 | 2017 |
Computational and experimental studies of the interaction between phospho-peptides and the C-terminal domain of BRCA1 VM Anisimov, A Ziemys, S Kizhake, Z Yuan, A Natarajan, CN Cavasotto Journal of computer-aided molecular design 25, 1071-1084, 2011 | 30 | 2011 |
Clinical and biomarker results from phase I/II study of PI3K inhibitor BYL 719 (alpelisib) plus nab-paclitaxel in HER2-negative metastatic breast cancer. P Sharma, VG Abramson, A O'Dea, HB Pathak, ZY Pessetto, YY Wang, ... Journal of Clinical Oncology 36 (15_suppl), 1018-1018, 2018 | 28 | 2018 |
Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design Z Yuan, EA Kumar, SJ Campbell, NY Palermo, S Kizhake, JNM Glover, ... ACS medicinal chemistry letters 2 (10), 764-767, 2011 | 26 | 2011 |
Epimorphin-induced MET sensitizes ovarian cancer cells to platinum KH Yew, J Crow, J Hirst, Z Pressetto, AK Godwin PloS one 8 (9), e72637, 2013 | 24 | 2013 |
Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection N He, S Thippabhotla, C Zhong, Z Greenberg, L Xu, Z Pessetto, ... Communications Biology 5 (1), 660, 2022 | 22 | 2022 |
Acute myeloid leukemia or myelodysplastic syndrome with chromosome 17 abnormalities and long-term outcomes with or without hematopoietic stem cell transplantation A Britt, GR Mohyuddin, B McClune, A Singh, T Lin, S Ganguly, ... Leukemia Research 95, 106402, 2020 | 19 | 2020 |
Structure–activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1 Z Yuan, EA Kumar, S Kizhake, A Natarajan Journal of medicinal chemistry 54 (12), 4264-4268, 2011 | 19 | 2011 |
Evaluation of the durability of the immune humoral response to COVID-19 vaccines in patients with cancer undergoing treatment or who received a stem cell transplant QJ Khan, CR Bivona, GA Martin, J Zhang, B Liu, J He, KH Li, M Nelson, ... JAMA oncology 8 (7), 1053-1058, 2022 | 18 | 2022 |
Food-derived polyphenols inhibit the growth of ovarian cancer cells irrespective of their ability to induce antioxidant responses Y Kwon Heliyon 4 (8), 2018 | 18 | 2018 |
Design, optimization, and multisite evaluation of a targeted next-generation sequencing assay system for chimeric RNAs from gene fusions and exon-skipping events in non–small … RA Blidner, BC Haynes, S Hyter, S Schmitt, ZY Pessetto, AK Godwin, ... The Journal of Molecular Diagnostics 21 (2), 352-365, 2019 | 16 | 2019 |
Developing a genetic signature to predict drug response in ovarian cancer S Hyter, J Hirst, H Pathak, ZY Pessetto, DC Koestler, R Raghavan, D Pei, ... Oncotarget 9 (19), 14828, 2018 | 16 | 2018 |