Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation SH Hu, MP Christie, NJ Saez, CF Latham, R Jarrott, LHL Lua, BM Collins, ... Proceedings of the National Academy of Sciences 108 (3), 1040-1045, 2011 | 121 | 2011 |
Low-resolution solution structures of Munc18: Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide MP Christie, AE Whitten, GJ King, SH Hu, RJ Jarrott, KE Chen, AP Duff, ... Proceedings of the National Academy of Sciences 109 (25), 9816-9821, 2012 | 70 | 2012 |
The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane S Martin, VM Tomatis, A Papadopulos, MP Christie, NT Malintan, ... Journal of cell science 126 (11), 2353-2360, 2013 | 56 | 2013 |
Cholesterol-dependent cytolysins: from water-soluble state to membrane pore MP Christie, J Bronte A, RK Tweten, P Michael W, M Craig J Biophysical Reviews 10 (5), 1337-1348, 2018 | 51 | 2018 |
Nanosized, peptide-based multicomponent DNA delivery systems: optimization of endosome escape activity Y Wan, PM Moyle, MP Christie, I Toth Nanomedicine 11 (8), 907-919, 2016 | 23 | 2016 |
A key motif in the cholesterol-dependent cytolysins reveals a large family of related proteins JC Evans, BA Johnstone, SL Lawrence, CJ Morton, MP Christie, ... MBio 11 (5), 10.1128/mbio. 02351-20, 2020 | 17 | 2020 |
Biophysical characterization of lectin–glycan interactions for therapeutics, vaccines and targeted drug-delivery MP Christie, I Toth, P Simerská Future Medicinal Chemistry 6 (18), 2113-2129, 2014 | 16 | 2014 |
A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation MP Christie, P Simerska, FEC Jen, WM Hussein, MFM Rawi, ... PloS one 9 (4), e95024, 2014 | 16 | 2014 |
Cholesterol‐dependent cytolysins: The outstanding questions BA Johnstone, R Joseph, MP Christie, CJ Morton, C McGuiness, ... IUBMB life 74 (12), 1169-1179, 2022 | 14 | 2022 |
The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin K Wade, SL Lawrence, AJ Farrand, EM Hotze, MJ Kuiper, MA Gorman, ... MBio 10, e00538-19, 2019 | 13 | 2019 |
X-ray crystallography shines a light on pore-forming toxins BA Johnstone, MP Christie, CJ Morton, MW Parker Methods in Enzymology 649, 1-46, 2021 | 11 | 2021 |
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure KMR Faysal, JC Walsh, N Renner, CL Márquez, VB Shah, AJ Tuckwell, ... Elife 13, e83605, 2024 | 9 | 2024 |
α-1, 4-Galactosyltransferase-catalyzed glycosylation of sugar and lipid modified Leu-enkephalins P Simerska, MP Christie, D Goodwin, FEC Jen, MP Jennings, I Toth Journal of Molecular Catalysis B: Enzymatic 97, 196-202, 2013 | 9 | 2013 |
Single-molecule analysis of the entire perfringolysin O pore formation pathway C McGuinness, JC Walsh, C Bayly-Jones, MA Dunstone, MP Christie, ... Elife 11, e74901, 2022 | 8 | 2022 |
The nature of the Syntaxin4 C-terminus affects Munc18c-supported SNARE assembly A Rehman, SH Hu, Z Tnimov, AE Whitten, GJ King, RJ Jarrott, ... PLoS One 12 (8), e0183366, 2017 | 8 | 2017 |
Peptide based DNA nanocarriers incorporating a cell-penetrating peptide derived from neurturin protein and poly-L-lysine dendrons N Rosli, MP Christie, PM Moyle, I Toth Bioorganic & Medicinal Chemistry 23 (10), 2470-2479, 2015 | 8 | 2015 |
Liposomes for improved enzymatic glycosylation of lipid-modified lactose enkephalin MP Christie, P Simerska, FEC Jen, MP Jennings, I Toth ChemPlusChem 78 (8), 793, 2013 | 6 | 2013 |
Revisiting interaction specificity reveals neuronal and adipocyte Munc18 membrane fusion regulatory proteins differ in their binding interactions with partner SNARE Syntaxins MP Christie, SH Hu, AE Whitten, A Rehman, RJ Jarrott, GJ King, ... Plos one 12 (10), e0187302, 2017 | 5 | 2017 |
Milligram Quantities of Homogeneous Recombinant Full-Length Mouse Munc18c from Escherichia coli Cultures A Rehman, RJ Jarrott, AE Whitten, GJ King, SH Hu, MP Christie, ... PLoS One 8 (12), e83499, 2013 | 5 | 2013 |
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria HL Abrahamsen, TC Sanford, CE Collamore, BA Johnstone, MJ Coyne, ... Nature Communications 15 (1), 5028, 2024 | | 2024 |